Bambusuril Macrocycles for the Binding and release of Sulfide and
Hydrosulfide Anions in Water
Julián Vázquez and Vladimir Šindelář
Department of Chemistry and RECETOX, Masaryk University,
Kamenice 5, 625 00, Brno, Czech Republic
Email: sindelar@chemi.muni.cz
Abstract
Hydrogen sulfide (H2S) has become an important target for research due to its physiological
properties and potential applications in medicine.1-3
Many synthetic molecules have been
reported as exogenous H2S sources, which rely on chemical reactions for the delivery of the
H2S.4-6
Bambusurils (BU) are a family of host macrocycles that bind inorganic and organic
anions with high affinity and selectivity in both organic and aqueous media.7-9
In this work,
supramolecular binding of sulfide (S2)
and hydrosulfide (HS)
anions by a synthetic receptor
in water have been studied for the first time. Bambusuril macrocycles (BU) were used to
stabilize these anions in its cavity following by their release into water.10
Figure 1. Energy-optimized geometry of the Bambusuril complex with sulfide anion.
Acknowledgments
This work was supported by the Czech Science Foundation (18-21801S) and by the
RECETOX Research Infrastructure (LM2015051 and CZ.02.1.01/0.0/0.0/16_013/0001761).
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