Evidence-based medicine is, simply put, an approach that combines the expertise of the physician, the latest and best research findings with the patient's values and attitudes towards treatment. In this session, we will focus on how to recognize quality data, how to navigate clinical trial results, and how to interpret them. And since last week's topic was antithrombotic drugs, we will practice our skills of critically reading clinical trials on those.

So let's start with the pre-class reading (chapter 1 in the book). The link can be found here:

Taking into account the complexity of the whole issue of designing and interpreting clinical trials, we have supplemented the pre-class reading with several video lectures that deal with selected aspects in more detail. The first of these talks about clinical trial designs because, as you might guess, we don't always make do with the basic design of, for example, one treated and one untreated arm. This video lecture is 15 minutes long. Join us and come watch it with us.

The second video lecture then discusses the interpretation of clinical trial results and supplements, explains and paraphrases the text from the pre-class reading, which can make it easier to understand. The length of the video lecture is 26 minutes.

Hand in hand with the previous issue is the question of the evaluation of statistics in clinical trials. So here is just a simple 23-minute lecture on the basics of statistics.

Handouts for all video lectures can be found here:

Test your knowledge after reading the pre-class reading chapters and listening to the complementary lectures.

Try taking the ROPOT test here:

And now you can look forward to the TBL lesson where we will focus on the reading of clinical trials and guidelines and application to a virtual patient.