Týden 9 - Sex Determination in Juvenile and Infant Remains Using Dimorphic Enamel Peptide Analysis
Záznam semináře
Heidi Shaw
Archaeology Department, Durham University. Lower Mount Joy, South Rd, Durham DH1 3LE, United Kingdom
Sex Determination in Juvenile and Infant Remains Using Dimorphic Enamel Peptide Analysis
Abstract: The determination of biological sex is fundamental to the study of past human
populations. It represents the platform by which bioarchaeologists base many subsequent
analyses, such as age-at death and stature, and interpretations about demography,
epidemiology, human identity, and social organisation. Traditional sex determination methods
in bioarchaeology are reliant on the presence of sexually dimorphic skeletal elements, which
are not always preserved in archaeological contexts, and are not reliable for assessing sex of
infants or juveniles. Using an innovative method for sex determination, it is now possible to
accurately identify the sex of infants and children. The method identifies sex chromosomelinked isoforms of the peptide amelogenin from human tooth enamel using a minimally
destructive acid etching procedure and subsequent nanoflow liquid chromatography mass
spectrometry (nanoLC-MS). The implications of this method for our understanding of
palaeodemographics and childhood mortality and morbidity in the past are also explored.
Bio: Heidi is a 2nd year PhD student at Durham University. After completing a B.A. in
Archaeology at the Australian National University, she completed a MSc in Palaeopathology
at Durham University in 2013 and a MPH at George Washington University in 2019. Her
research focuses on biochemical analyses of human teeth for information related to sex,
migration, and health. She is also interested in exploring the integration of interdisciplinary
research between the fields of public health and palaeopathology.