aZLBI0222p Biology II - lecture

Faculty of Medicine
spring 2023
Extent and Intensity
1/0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (lecturer)
Mgr. Kateřina Francová, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Jana Růžičková (assistant)
Guaranteed by
prof. MUDr. Iva Slaninová, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Francová, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Thu 16. 2. 13:00–13:50 C15/309, Thu 23. 2. 13:00–13:50 C15/309, Thu 2. 3. 13:00–13:50 C15/309, Thu 9. 3. 13:00–13:50 C15/309, Thu 16. 3. 13:00–13:50 C15/309, Thu 23. 3. 13:00–13:50 C15/309, Thu 30. 3. 13:00–13:50 C15/309, Thu 6. 4. 13:00–13:50 C15/309, Thu 13. 4. 13:00–13:50 C15/309, Thu 20. 4. 13:00–13:50 C15/309, Thu 27. 4. 13:00–13:50 C15/309, Thu 4. 5. 13:00–13:50 C15/309, Thu 18. 5. 13:00–13:50 C15/309
Prerequisites
aZLBI0121c Biology I - pract.
Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisites for studying the course. Expected knowledge for each lecture is specified in the course syllabus. The literature recommended to study for each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- understanding of the basic principles of human genetics
- understanding of the mechanisms of cancer development
- acquaintance with the basics of genomics, immunogenetics, epigenetics, gene therapy, tissue engineering, evolutionary biology, human ontogeny
Learning outcomes
After completing the course, the student will be able to:
- explain and apply basic principles of human genetics
- explain the role of medical biology in the development of modern therapies (e.g. molecular therapies of cancer)
- explain the basic principles of current methods used in gene therapy and cell therapies
- understand the significance of the human microbiome in human health and disease
- be knowledgeable in basic modern approaches to studying various diseases and to personalised medicine (genomics)
Syllabus
  • Introduction to Genetics I – Genetics in Medicine, Mendelian Inheritance, Autosomal and Gonosomal Inheritance, Chromosome Abnormalities
  • Introduction to Genetics II – Multifactorial Inheritance, Genetic Linkage, Population Genetics
  • Human genome and methods of its study
  • Epigenetics – Interaction of Genes and Environment
  • Immunogenetics
  • Cancer Biology I – Carcinogenesis, Hallmarks of Cancer
  • Cancer Biology II – Oncogenes and tumour suppressors, oncogenic viruses
  • Bacterial and Viral Genomics
  • Use of knowledge of molecular biology and genetics in medicine
  • Gene Therapy
  • Human Microbiome
  • Stem Cells and Tissue Engineering
  • Evolutionary Biology
  • Introduction to human ontogeny (pre- and postnatal development)
Literature
    required literature
  • ALBERTS, Bruce, Karen HOPKIN, Alexander JOHNSON, David Owen MORGAN, Martin C. RAFF, Keith ROBERTS and Peter WALTER. Essential cell biology. International student editio. New York: W.W Norton, 2019, xxxii, 734. ISBN 9780393680393. info
    recommended literature
  • SNUSTAD, D. Peter and Michael J. SIMMONS. Principles of genetics. Sixth edition. Hoboken: John Wiley & Sons, 2012, xviii, 766. ISBN 9780470903599. info
Teaching methods
lecture every week
Assessment methods
The course of Biology II builds on the knowledge gained from Biology I and is completed with an oral exam based on topics discussed at lectures and practices of both semesters.
Language of instruction
English
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 15.
Listed among pre-requisites of other courses

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Teacher's information
https://is.muni.cz/auth/el/med/jaro2023/aZLBI0222p/index.qwarp
Lectures take place every week. We recommend to follow the Interactive syllabus of the course where students can find all relevant information (schedule, substitutions, public holidays etc.), and also corresponding study literature for each week. https://is.muni.cz/auth/el/med/jaro2023/aZLBI0222p/index.qwarp
The course is also listed under the following terms Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2024, spring 2025.
  • Enrolment Statistics (spring 2023, recent)
  • Permalink: https://is.muni.cz/course/med/spring2023/aZLBI0222p