C8500 Organic Reaction Mechanisms

Faculty of Science
Spring 2016
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
prof. RNDr. Petr Klán, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Petr Klán, Ph.D.
Department of Chemistry – Chemistry Section – Faculty of Science
Supplier department: Department of Chemistry – Chemistry Section – Faculty of Science
Timetable
Mon 9:00–10:50 A08/309
Prerequisites
C7410 Structure and Reactivity &&NOW( C8510 Org. React. Mechanisms-sem. )
organic chemistry, physical chemistry
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
This course is a logical counterpart of the course of Structure and Reactivity. In the end of this course, the student will be able to understand the details of the mechanisms of chemical transformations, which are studied using chemical and physical tools. Knowledge of elemental steps of chemical transformations and reactive intermediates will help the student to understand the scientific literature in the corresponding field and interpret the results from the experimental and theoretical studies.
Syllabus
  • 1. Art of writing the reaction mechanism. 2. How chemistry studies the reaction mechanisms. 3. Reactive intermediates. Radicals, carbebes, nitrenes etc. 4. Pericylic reactions. Selection rules. 5. Nucleophilic aliphatic and aromatic substitution. 6. Eliminations. 7. Electrophilic aromatic substitution. 8. Additions to C=C bond. 9. Reactions of carbonyl compounds 10. Rearrangements. 11. Free radical reactions. 12. Oxidation and reductions. 13. Transient metal catalysis. 14. Photochemical reactions.
Literature
  • E. V. Anslyn, D. A. Dougherty: Modern Physical Organic Chemistry. University Science Books, Sausalito, California 2005. ISBN 1-891389-
  • A: Jurášek: Fyzikálne princípy a mechanizmy organických reakcií. Veda, Bratislava 1989.
  • O. Červinka: Mechanismy organických reakcí. SNTL/ALFA, Praha 1981.
Teaching methods
Lectures.
Assessment methods
One written final test (50% of correct answers is needed to pass) + the oral exam.
Language of instruction
Czech
Follow-Up Courses
Further Comments
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/1431/jaro2006/C8500/
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.
  • Enrolment Statistics (Spring 2016, recent)
  • Permalink: https://is.muni.cz/course/sci/spring2016/C8500