Bi6336 Biology of germ-cells

Faculty of Science
Spring 2023
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
doc. MVDr. Martin Anger, CSc. (lecturer)
prof. MVDr. Jiří Rubeš, CSc. (lecturer)
doc. RNDr. Martin Vácha, Ph.D. (assistant)
Guaranteed by
doc. MVDr. Martin Anger, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: doc. MVDr. Martin Anger, CSc.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Mon 16:00–17:50 D36/212
Prerequisites (in Czech)
Bi4020 Molecular biology
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Essential molecular mechanisms controlling germ cells development, fertilization and early embryonic development in mammals will be presented. Also the most important causes of developmental failures and their consequences and currently used techniques and methods in human assisted reproduction and research focused on germ cells and embryos will be discussed.
Learning outcomes
At the end of the course students should be able to: - understand the molecular mechanisms controlling development of germ cells and early embryos in mammals - characterize the major events during fertilization and subsequent early embryonic development in mammals - identify the most important causes of developmental failures of mammalian germ cells or early embryos - summarize the main methods and approaches used in artificial human reproduction
Syllabus
  • 1. Control mechanisms of chromosome segregation in somatic cells and germ cells (mitosis, meiosis). 2. Molecular mechanism controlling fertilization and early development in mammals. 3. Major chromosome segregation errors in germ cells and embryos, their causes and consequences for human reproduction. 4. Chromosomal rearangemets, their impact in evolution and consequences for human reproduction. 5. Current methods and appoaches in human assisted reproduction and techniques used to analyze chromosomal content of germ cells and embryos. 6. New trends and methods used in research focused on germ cells and embryos
Literature
    recommended literature
  • ALBERTS, Bruce, Alexander JOHNSON, Julian LEWIS, David Owen MORGAN, Martin C. RAFF, Keith ROBERTS and Peter WALTER. Molecular biology of the cell. Edited by John H. Wilson - Tim Hunt. Sixth edition. New York, NY: Garland Science, 2014, xxxiv, 134. ISBN 9780815344322. info
Teaching methods
Content of this course include lectures, presentation, discussions and other resources provided by the lecturer.
Assessment methods
The course is completed by oral exam during which the themes from the lectures are discussed. Student must prove sufficient knowledge of lecture content.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
General note: Určeno pro doktorské a magisterské studium biologie.
The course is also listed under the following terms Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, spring 2018, Spring 2020, Spring 2021, Spring 2022, Spring 2024, Spring 2025.
  • Enrolment Statistics (Spring 2023, recent)
  • Permalink: https://is.muni.cz/course/sci/spring2023/Bi6336