PřF:Bi5040 Biostatistics - basic course - Course Information
Bi5040 Biostatistics - basic course
Faculty of ScienceAutumn 2011
- Extent and Intensity
- 3/0/0. 3 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
- Teacher(s)
- RNDr. Jiří Jarkovský, Ph.D. (lecturer)
- Guaranteed by
- prof. RNDr. Ladislav Dušek, Ph.D.
RECETOX – Faculty of Science
Contact Person: RNDr. Jiří Jarkovský, Ph.D. - Timetable
- Wed 17:00–19:50 B11/132
- Prerequisites
- None - basic course.
- Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- Cellular and Molecular Diagnostics (programme PřF, B-BI)
- Molecular Biology and Genetics (programme PřF, B-BI)
- Molecular Biology and Genetics (programme PřF, B-EXB)
- General Biology (programme PřF, B-BI, specialization Ekotoxikology)
- General Biology (programme PřF, B-BI, specialization Plant Physiology)
- General Biology (programme PřF, B-BI, specialization Physiology of Animals)
- General Biology (programme PřF, B-BI, specialization Microbiology)
- Special Biology (programme PřF, B-EXB)
- Special Biology (programme PřF, B-EXB, specialization Ecotoxicology)
- Special Biology (programme PřF, B-EXB, specialization Experimental Biology of Plants)
- Special Biology (programme PřF, B-EXB, specialization Experimental Biology of Animals and Immunology)
- Special Biology (programme PřF, B-EXB, specialization Mikrobiology a Molecular Biotechnology)
- Course objectives
- At the end of the course the students are able to: Define structure of dataset for statistical analysis; Visualize the data and interpret data visualisation; Identify correct methods of descriptive statistics; Formulate hypothesis for statistical testing; Select the correct statistical tests for hypotheses confirmation/refusal; Interpret results of statistical evaluation, both analysis of own data and statistics in scientific literature; Assess the applicability of statistical methods on various types of data.
- Syllabus
- Introduction to statistics, testing of hypotheses.
- Tables of distribution functions. Sampling from biological populations, data processing.
- Introduction to sampling design. Continuous, ordinal and nominal data in biology.
- Distribution of continuous and bivariate variables - testing of hypotheses, graphical methods.
- Application of binomial and Poisson distribution in biology.
- One sample testing: sample mean, median, standard deviation, variance, binomial p and Poisson constant.
- Two sample testing. Experimental design - randomized and blocked. Parametric and non - parametric methods.
- Application of goodness-of-fit test in biology, analysis of R x C contingency tables, discrimination of categorical data.
- Measures of similarity in ecology (covariance, correlation coefficients, similarity coefficients).
- Analysis of variance (ANOVA): one-way and two-way model.
- Simple linear regression. Linear regression. Introduction to multivariate linear regression.
- Experimental design: one-way and two-way models; factorial design, randomized blocks. Laboratory and field trials. Nested design of ANOVA in genetics and ecology. Non - parametric ANOVA.
- Literature
- Petrie, A., Watson, P. (2006) Statistics for Veterinary and Animal Science, Wiley-Blackwell; 2nd ed
- Zar, J.H. (1998) Biostatistical analysis. Prentice Hall, London. 4th ed.
- Sokal, R.R., Rohlf, F.J. (1994) Biometry, W. H. Freeman, 3th ed.
- Teaching methods
- Theoretical lectures supplemented by commented examples; students are encouraged to ask quaetions about discussed topics.
- Assessment methods
- Biostatistics course is finished by written exam aimed on principles, prerequisties and correct selection of methods for solution of practical examples.
- Language of instruction
- Czech
- Follow-Up Courses
- Further Comments
- Study Materials
The course is taught annually. - Listed among pre-requisites of other courses
- Bi5180 Quantitative genetics
Bi3060 && Bi5040 || E5540 - Bi7920 Analysis of biological data
Bi5040||Bi5560 - Bi7921 Advanced methods of analysis of biological data
(Bi5040||Bi5560) && Bi7920 - E7490 Advanced non-parametric methods
Bi5040 || Bi5045 - E7528 Analysis of genomic and proteomic data
(Bi5040 || Bi5045 || Bi5046 || E5046) && E8600 && E7527 && Bi4010 && E0034
- Bi5180 Quantitative genetics
- Teacher's information
- http://www.cba.muni.cz/vyuka/
- Enrolment Statistics (Autumn 2011, recent)
- Permalink: https://is.muni.cz/course/sci/autumn2011/Bi5040