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Vybrané publikace/výsledky
Robust and highly accurate automatic NOESY assignment and structure determination with Rosetta (2014)
Carboxy-terminal polyglutamylation regulates signaling and phase separation of the Dishevelled protein (2024)
A Novel Protein-Protein Interaction in the RES (REtention and Splicing) Complex (2014)
Efficient large-scale preparation and purification of short single-stranded RNA oligonucleotides (2016)
Cloning, expression and purification of the human Islet Amyloid Polypeptide (hIAPP) from Escherichia coli (2015)
Impact of structural stability of cold adapted Candida antarctica lipase B (CaLB): in relation to pH, chemical and thermal denaturation (2015)
HU histone-like DNA-binding protein from Thermus thermophilus: structural and evolutionary analyses (2016)
p53 Specifically Binds Triplex DNA In Vitro and in Cells (2016)
A rapid method for detecting protein-nucleic acid interactions by protein induced fluorescence enhancement (2016)
Visualization of stable ferritin complexes with palladium, rhodium and iridium nanoparticles detected by their catalytic activity in native polyacrylamide gels (2017)
The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes (2017)
Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19 (2017)
Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites (2017)
Conformational Selection of Dimethylarginine Recognition by the Survival Motor Neuron Tudor Domain (2018)
Automated NMR resonance assignments and structure determination using a minimal set of 4D spectra (2018)
hIAPP forms toxic oligomers in plasma (2018)
De novo design of a non-local beta-sheet protein with high stability and accuracy (2018)
Insight on specificity of uracil permeases of the NAT/NCS2 family from analysis of the transporter encoded in the pyrimidine utilization operon of Escherichia coli (2018)
Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1 (2019)
Selective isotope labeling for NMR structure determination of proteins in complex with unlabeled ligands (2019)
Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors (2019)
CDK12 controls G1/S progression by regulating RNAPII processivity at core DNA replication genes (2019)
Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs (2019)
WNT signaling inducing activity in ascites predicts poor outcome in ovarian cancer (2020)
4D-CHAINS/autoNOE-Rosetta, an automatedpipeline for rapid NMR structure determination (2019)
Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling (2020)
12-O-Tetradecanoylphor bol-13-acetate increases cardiomyogenesis through PKC/ERK signaling (2020)
RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer (2020)
Phosphorylation-induced changes in the PDZ domain of Dishevelled 3 (2021)
(E)-2-(2-Allylidenehydrazinyl)thiazole derivatives: Design, green synthesis, in silico and in vitro antimycobacterial and radical scavenging studies (2020)
4D-GRAPHS (2021)
Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding (2021)
The order of PDZ3 and TrpCage in fusion chimeras determines their properties-a biophysical characterization (2021)
Fusion of two unrelated protein domains in a chimera protein and its 3D prediction: Justification of the x-ray reference structures as a prediction benchmark (2022)
Recognition and coacervation of G-quadruplexes by a multifunctional disordered region in RECQ4 helicase (2023)
4D-CHAINS (2021)
CRISPR CAS9 ENGINEERED TETRASPANIN DEFICIENT CELL LINES FOR THE ANALYSIS OF EXTRACELLULAR VESICLES (2023)
Lipidomic analysis of tetraspanin-deficient extracellular vesicles (2024)
Lipidomic profiling of extracellular vesicles from tetraspanin-deficient cell lines (2024)
Proteomic analysis of tetraspanin-deficient extracellular vesicles (2024)
Slizniční pemfigoid s očním postižením. Série případů (2024)
Mucous membrane pemphigoid diagnostics with western blot analysis (2024)
Studying Weak and Dynamic Interactions of Posttranslationally Modified Proteins using Expressed Protein Ligation (2014)
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