Vyhledávání publikací

Vybrané publikace/výsledky

EMBO DNA Repair Forum (2008)
Characterization of Srs2 role in recombination (2008)
Biochemical characterization of Srs2 helicase (2008)
Význam proteinů Srs2 a Mus81/MMS4 během opravy DNA. (2008)
Co-operativity of Mus81-Mms4 with Rad54 in the resolution of recombination and replication intermediates. (2009)
Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination. (2009)
DNA repair mechanisms in yeast (2009)
DNA OPRAVA A NESTABILITA GENOMU (2009)
Rad52 sumoylation affects the efficiency of the recombination and repair (2009)
Srs2 Disassembles Rad51 Filaments by a Protein-Protein Interaction Triggering ATP Turnover and Dissociation of Rad51 from DNA (2009)
Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo (2009)
Biophysical Studies on the Stability of DNA Intrastrand Cross-Links of Transplatin (2008)
Binding of mismatch repair protein MutS to mispaired DNA adducts of intercalating ruthenium(II) arene complexes (2008)
DNA repair and its quality control (2009)
Regulation of Rad51 recombinase presynaptic filament assembly via interactions with the Rad52 mediator and the Srs2 anti-recombinase. (2009)
The Rad54 protein seed DNA repair synthesis (2009)
Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption. (2009)
Srs2: the Odd-Job Man in DNA repair (2010)
Cdk1 targets Srs2 to complete synthesis-dependent strand annealing and to promote (2010)
Rad52 Sumoylation Affects the Efficiency of the Recombination and DNA Repair (2009)
Rad52 Sumoylation Affects the Efficiency of the Recombination and DNA Repair (2009)
Rad52 SUMOylation affects the efficiency of the DNA repair (2010)
S-pombe genome deletion project. An update (2010)
SUMOylation is required for normal development of linear elements and wild-type meiotic recombination in Schizosaccharomyces pombe. (2010)
Reconstitution of DNA repair synthesis in vitro and the role of polymerase and helicase activities (2011)
Unwinding of synthetic replication and recombination substrates by Srs2 (2012)
Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation. (2012)
SUMO Wrestles with Recombination (2012)
Homologous recombination and its regulation (2012)
Charakterizace role proteinu RecQ4 v homologní rekombinaci (2013)
Lif1 SUMOylation and its role in non-homologous end-joining (2013)
Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis (2013)
Role of PCNA and TLS polymerases in D-loop extension during homologous recombination in humans (2013)
Strand invasion by HLTF as a mechanism for template switch in fork rescue (2014)
The PCNA Interaction Protein Box Sequence in Rad54 Is an Integral Part of Its ATPase Domain and Is Required for Efficient DNA Repair and Recombination (2013)
Light-Switchable Polymer from Cationic to Zwitterionic Form: Synthesis, Characterization, and Interactions with DNA and Bacterial Cells (2013)
Sumoylation of the Rad1 nuclease promotes DNA repair and regulates its DNA association (2014)
Nucleases in homologous recombination as targets for cancer therapy (2014)
Exploring synthetic lethal interaction between Checkpoint Kinase 1(CHK1) and DNA replication stress (2014)
A Versatile Scaffold Contributes to Damage Survival via Sumoylation and Nuclease Interactions (2014)
Sumoylation Influences DNA Break Repair Partly by Increasing the Solubility of a Conserved End Resection Protein (2015)
Structure and Dynamics of DNA Duplexes Containing a Cluster of Mutagenic 8-Oxoguanine and Abasic Site Lesions (2014)
Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates (2015)
RECQ4 selectively recognizes Holliday junctions (2015)
Rad51 Paralogs Remodel Pre-synaptic Rad51 Filaments to Stimulate Homologous Recombination (2015)
MEK and TGF-beta Inhibition Promotes Reprogramming without the Use of Transcription Factor (2015)
Biological Small Angle X-ray Scattering at CEITEC-MU (2015)
Sumoylation regulates EXO1 stability and processing of DNA damage (2015)
Chronic lymphocytic leukemia cells are highly susceptible to direct inhibition of checkpoint kinase (2015)
Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication (2015)
Phosphorylation of Elg1 regulates its activity (2015)
Nanostrukturovaný povrch pro studium mezibuněčných interakcí kmenových buněk (2015)
Nanostructured surfaces as a promising tool for studying the cellular interactions (2015)
Novel approach for studying of cell interactions via nanostructured surfaces (2015)
Preparation of nanostructured molecular lawn as tool for studying the cellular interactions (2015)
Yeast mitochondrial HMG proteins: DNA-binding properties of the most evolutionarily divergent component of mitochondrial nucleoids (2016)
Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells (2015)
The structure and DNA-binding properties of Mgm101 from a yeast with a linear mitochondrial genome (2016)
Cancer TARGETases: DSB Repair as a Pharmacological Target (2016)
Human Rap1 modulates TRF2 attraction to telomeric DNA (2015)
Nanostrukturování povrchů jako slibný nástroj pro studium buněčných interakcí kmenových buněk (2016)
Nanostructured Surfaces for Studying the Cellular Interactions (2016)
DSB formation by Spo11 protein requires interaction with Mre11 (2016)
Nanostructured molecular lawn-powerful tool for studying cellular interactions (2016)
PRDM9 forms a multiprotein complex tethering recombination hotspots to the chromosomal axis (2016)
Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance (2016)
Pro-recombination Role of Srs2 Protein Requires SUMO (Small ubiquitin-like Modifier) but Is Independent of PCNA (Proliferating Cell Nuclear Antigen) Interaction (2016)
DNA, the central molecule of aging (2016)
Mitochondrial dysfunction in DDR-related cancer predisposition syndromes (2016)
The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis (2016)
Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission (2016)
SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination (2016)
Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains (2017)
PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis (2017)
Unloading of homologous recombination factors is required for restoring double-stranded DNA at damage repair loci (2017)
A Polar and Nucleotide-Dependent Mechanism of Action for RAD51 Paralogs in RAD51 Filament Remodeling (2016)
A structure-function analysis of the yeast Elg1 protein reveals the importance of PCNA unloading in genome stability maintenance (2017)
Reprint of "DNA, the central molecule of aging" (2016)
Direct nanopatterning of biomolecules by electron beam lithography for studying of cellular interaction (2017)
Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation (2017)
RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis (2017)
Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments (2017)
Fanconi-Anemia-Associated Mutations Destabilize RAD51 Filaments and Impair Replication Fork Protection (2017)
Role of PCNA and RFC in promoting Mus81-complex activity (2017)
Pyrazolotriazines as inhibitors of nucleases (2017)
Pyrazolotriazines as inhibitors of nucleases (2018)
Genetic analysis of a relation between SMC5/6 and SAGA chromatin modifying complex (2018)
Genetic analysis of a relation between SMC5/6 and SAGA chromatin modifying complex (2018)
Pyrazolotriazines as inhibitors of nucleases (2018)
A residue of motif III positions the helicase domains of motor subunit HsdR in restriction-modification enzyme EcoR124I (2018)
Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state (2018)
SAMHD1 acts at stalled replication forks to prevent interferon induction (2018)
CDK12 kinase activity controls G1/S progression by regulating optimal transcription of core DNA replication genes (2018)
CDK12 controls G1/S progression by regulating RNAPII processivity at core DNA replication genes (2019)
Sumoylation regulates the stability and nuclease activity of Saccharomyces cerevisiae Dna2 (2019)
Deficiency and haploinsufficiency of histone macroH2A1.1 in mice recapitulate hematopoietic defects of human myelodysplastic syndrome (2019)
7-hydroxyfrullanolide, isolated from Sphaeranthus indicus, inhibits colorectal cancer cell growth by p53-dependent and -independent mechanism (2019)
Mussel-mimicking sulfobetaine-based copolymer with metal tunable gelation, self-healing and antibacterial capability (2020)
Characterizing the interaction between Rad54 and PCNA. (2017)
The CHK1 inhibitor MU380 significantly increases the sensitivity of human docetaxel-resistant prostate cancer cells to gemcitabine through the induction of mitotic catastrophe (2020)
Substituted propanamides as inhibitors of nucleases (2020)
DSS1 interacts with and stimulates RAD52 to promote the repair of DSBs (2020)
WRN modulates translation by influencing nuclear mRNA export in HeLa cancer cells (2020)
RAD51-dependent recruitment of TERRA lncRNA to telomeres through R-loops (2020)
Antibiotic-induced DNA damage results in a controlled loss of pH homeostasis and genome instability (2020)
TREX2 Exonuclease Causes Spontaneous Mutations and Stress-Induced Replication Fork Defects in Cells Expressing RAD51(K133A) (2020)
SAMHD1 acts at stalled replication forks to prevent interferon induction (2020)
Single-molecule visualization of human RECQ5 interactions with single-stranded DNA recombination intermediates (2021)
Nucleotide proofreading functions by nematode RAD51 paralogs facilitate optimal RAD51 filament function (2021)
In Vitro Characterization of Sumoylation of HR Proteins (2021)
SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES (2021)
Mendel Lectures 2002–2022 (2022)
Mendel Lectures 2002–2022 (2022)
Geometric Control of Cell Behavior by Biomolecule Nanodistribution (2022)
ヌクレアーゼの阻害剤としての置換プロパンアミド (2022)
Substituted propanamides as inhibitors of nucleases (2022)
Substituted aminothiazoles as inhibitors of nucleases (2022)
Substituted propanamides as inhibitors of nucleases (2022)
ヌクレアーゼの阻害剤としての置換アミノチアゾール (2022)
The role of bivalent ions in the regulation of D-loop extension mediated by DMC1 during meiotic recombination (2022)
Substituted aminothiazoles as inhibitors of nucleases (2023)
MUS81 cleaves TOP1‑derived lesions and other DNA-protein cross‑links (2023)
Recognition and coacervation of G-quadruplexes by a multifunctional disordered region in RECQ4 helicase (2023)
Substituted aminothiazoles as inhibitors of nucleases (2023)
MutSβ-MutLβ-FANCJ axis mediates the restart of DNA replication after fork stalling at cotranscriptional G4/R-loops (2024)
Physical interaction with Spo11 mediates the localisation of Mre11 to chromatin in meiosis and promotes its nuclease activity (2024)
Concurrent D-loop cleavage by Mus81 and Yen1 yields half-crossover precursors (2024)
Mechanism of BCDX2-mediated RAD51 nucleation on short ssDNA stretches and fork DNA (2024)
eIF4F controls ERK MAPK signaling in melanomas with BRAF and NRAS mutations (2024)

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