Vyhledávání publikací

Vybrané publikace/výsledky

NMR mapping of the recombinant mouse major urinary protein I binding site occupied by the pheromone 2-sec-butyl-4,5-dihydrothiazole (1999)
An increase in protein backbone flexibility upon binding a hydrophobic ligand (1999)
Positive identification of the puberty-accelerating pheromone of the house mouse: the volatile ligands associating with the major urinary protein (1999)
Increased protein backbone conformational entropy upon hydrophobic ligand binding (1999)
Glycosylated major urinary protein of the house mouse: characterization of its N-linked oligosaccharides (2000)
Structural basis of pheromone binding to mouse major urinary protein (MUP-I) (2001)
NMR methodology for the study of nucleic acids (2001)
Measurement of small scalar and resiudal dipolar couplings in purine and pyrimidine bases (2001)
Exploring the Structure of a DNA Hairpin with the Help of NMR Spin-spin Coupling Constants: An Experimental and Quantum Chemical Investigation (2002)
Refinement of d(GCGAAGC) hairpin structure using one- and two-bond residual dipolar couplings (2002)
Pheromone binding by polymorphic mouse major urinary proteins (2002)
Recent biochemical insights into puberty acceleration, estrus induction and puberty delay in the house mouse (1999)
The effect of water on NMR spin-spin couplings in DNA: Improvement of calculated values by application of two solvent models (2003)
Internal Consistency of NMR Data Obtained in Partially Aligned Biomacromolecules (2003)
Temperature Dependent Spectral Density Analysis Applied to Monitoring Backbone Dynamics of Major Urinary Protein-I Complexed with the Pheromone 2-sec-Butyl-4,5-dihydrothiazole (2004)
NMR Distance Restraints At Low temperatures : An Application To DNA Hairpin (2005)
Refinement of Trypanosoma U6 RNA Stem-Loop Structure Using 1- and 2-Bond Residual Dipolar Couplings (2004)
New NMR Methods for Conformational Studies of Biomolecules (2005)
A new sensitive method for enzyme studies of rare glucosides (2005)
NMR Distance Restraints At Low Temperatures: Application To DNA Hairpin (2006)
Molecular dynamics study of major urinary protein-pheromone interactions: A structural model for ligand-induced flexibility increase (2006)
Analysis of NMR Distance Restraints - An Application To DNA and RNA Hairpins (2005)
NMR Study of Protein CD69 (2005)
1H, 13C, and 15N resonance assignment of Bombyx mori chemosensory protein 1 (BmorCSP1) (2006)
MD/DFT STUDY OF ENVIRONMENTAL EFFECTS ON 31P CHEMICAL SHIFT TENSORS IN B-DNA (2006)
Conformational Dependence of 31P Chemical Shift Tensors (2006)
A new, sensitive method for enzyme kinetic studies of scarce glucosides. (2006)
Conformational Dependence of 31P Chemical Shift Tensors in Nucleic Acids (2007)
Relationships between 31P Chemical Shift Tensors and Conformation of Nucleic Acid Backbobe: A DFT Study (2007)
Purine derivatives: Substituent effects as monitored by NMR (2007)
Backbone Motions of Free and Pheromone-Bound Major Urinary Protein I Studied by Molecular Dynamics Simulation (2007)
P-31 Chemical Shift Tensors in RNA and DNA Backbone. A DFT Study of Conformational Dependence and Its Implications for NMR Studies. (2007)
Structure of Bombyx mori chemosensory protein 1 in solution (2007)
Dynamics of major urinary protein-pheromone interactions: Insight by NMR and MD simulations (2007)
Purifikace a krystalizace přijímačové domény receptorové histidinkinázy CKI1 (2007)
Functional analysis of aglycone-binding site of the maize beta-glucosidase Zm-p60.1 (2007)
Funkční analýza aglykon-vazebného místa kukuřičné beta-glukozidázy Zm-p60.1 (2007)
¹³C CHEMICAL SHIFT TENSORS IN REGIOISOMERS OF N-SUBSTITUTED ADENINES (2008)
31P Chemical Shift Tensors for Canonical and Non-Canonical Nucleic Acid Conformations: DFT Calculations and NMR Implications. (2008)
1H, 13C, and 15N Resonance Assignment of the N-terminal Domain of Mason-Pfizer Monkey Virus Capsid Protein, CA1-140. (2008)
P-31 Chemical Shift Tensors in Nucleic Acids from the Quantum Chemistry Point of View (2008)
Oxidation and Nitrosylation of Cysteines Proximal to the Intermediate Filament (IF)-binding Site of Plectin (2007)
Calculation of 13C chemical shifts in Pseudoknot (2008)
Functional analysis of the aglycone - binding site of the maize beta-glucosidase Zm-p60.1 (2008)
Structure of CKI1RD, the receiver domain of the histidine kinase CKI1 from Arabidopsis thaliana (2008)
Inactivation of colicin Y by intramembrane helix helix interaction with its immunity protein (2008)
Experimental and quantum-chemical studies of 1H, 13C and 15N NMR coordination shifts in Au(III), Pd(II) and Pt(II) chloride complexes with picolines (2009)
Structural study of an RNA polymerase subunit unique for gram-positive bacteria (2009)
NMR study of a single-stranded DNA binding to the C-terminal domain of the protease from murine intracisternal A-type particle (2008)
NMR structural study of N-terminal domain of RNA polymerase delta subunit from Bacillus subtilis (2009)
Cloning, purification, crystallization and preliminary X-ray analysis of the receiver domain of the histidine kinase CKI1 from Arabidopsis thaliana. (2009)
Intermediate motions and dipolar couplings as studied by Lee-Goldburg cross-polarization NMR: Hartmann-Hahn matching profiles (2009)
NMR Structure of the N-Terminal Domain of Capsid Protein from the Mason-Pfizer Monkey Virus (2009)
Understanding the NMR Chemical Shifts for 6-halopurines: Role of Structure, Solvent, and Relativistic Effects (2009)
Investigation of Thermal Denaturation of Barley Nonspecific Lipid Transfer Protein 1 (ns-LTP1b) by Nuclear Magnetic Resonance and Differential Scanning Calorimetry (2009)
Program for Analysis of Internal Motion in Molecular Dynamics Simulation (2007)
NEW TOOLS FOR AN ANALYSIS OF EXPERIMENTAL (NMR) AND THEORETICAL (MD) DATA (2005)
Backbone 1H, 13C, and 15N NMR assignment for the inactive form of the retroviral protease of the murine intracisternal A-type particle, inMIA-14 PR (2009)
13C Chemical Shift Tensors in Hypoxanthine and 6-Mercaptopurine : Effects of Substitution, Tautomerism, and Intermolecular Interactions (2010)
MAGE (melanoma-associated antigen) Domain structural studies using NMR (2009)
Prediction of C-13 chemical shifts in nucleic acids (2009)
C-13 Chemical Shifts – Structure Relationships In Nucleic Acids (2009)
1H, 13C, and 15N NMR chemical shifts for selected glucosides and ribosides of aromatic cytokinins (2010)
Effects of magnesium binding and beryllofluoridation on a component of the cytokinin signaling pathway studied by nuclear magnetic resonance (2009)
NMR analyses of the receiver domain of CKI1 histidine kinase and its interaction with AHP proteins (2009)
S3EPY: a Sparky extension for determination of small scalar couplings from spin-state-selective excitation NMR experiments (2010)
Crystal structure of the receiver domain of the histidine kinase CKI1 from Arabidopsis thaliana (2009)
Crystal structure of CKI1 receiver domain from Arabidopsis (2009)
CRYSTALLIZATION AND X-RAY ANALYSIS OF THE RECEIVER DOMAIN OF THE HISTIDINE KINASE CKI1 FROM ARABIDOPSIS THALIANA (2009)
Actin-binding domain of mouse plectin. Crystal structure and binding to vimentin (2005)
Structure determination of an RNA polymerase subunit unique for gram-positive bacteria (2010)
Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase and its classification based on structural homologs (2010)
Expression cloning of lysis genes from polyvalent staphylococcal bacteriophage (2010)
Cloning and expression of endolysin and its SH3 domain from polyvalent staphylococcal bacteriophage (2010)
Cooperativity between subunits is essential for high affinity binding of N-acetylhexosamines to dimeric soluble and dimeric cellular forms of human CD69 (2010)
Synthetic N-acetylglucosamine based fully branched tetrasaccharide, a mimetic of the endogenous ligand for CD69, activates CD69+ NK cells and killer lymphocytes upon dimerization via a hydrophilic flexible linker (2010)
Backbone dynamics of N-terminal Domain of the Delta Subunit of Bacterial RNA Polymerase (2009)
ANALYSIS OF BACKBONE MOTIONS OF DELTA SUBUNIT OF RNA POLYMERASE FROM BACILLUS SUBTILIS (2010)
BACKBONE MOTIONS OF DELTA SUBUNIT OF RNA POLYMERASE FROM BACILLUS SUBTILIS ON VARIOUS TIME SCALES (2010)
Structure and dynamics of delta subunit of RNA polymerase from Bacillus subtilis (2010)
Understanding the NMR chemical shifts for 6-halopurines : role of structure, solvent and relativistic effects (2010)
Interpretation of Indirect Nuclear Spin_Spin Couplings in Isomers of Adenine: Novel Approach to Analyze Coupling Electron Deformation Density Using Localized Molecular Orbitals (2010)
Structure and dynamics of an RNA polymerase subunit unique for gram-positive bacteria (2010)
Carbon-detected Experiments for Assignment of Proline Rich Proteins (2010)
Chemical Shift Tensors in Isomers of Adenine: Relation to Aromaticity of Purine Rings? (2011)
Klonování a exprese lytických genů polyvalentního stafylokokového bakteriofága (2010)
Strategy for complete NMR assignment of disordered proteins with highly repetitive sequences based on resolution-enhanced 5D experiments (2010)
NMR as a tool for studies of (partially) disordered proteins and their interactions (2010)
Phosphorus Chemical Shifts in a Nucleic Acid Backbone from Combined Molecular Dynamics and Density Functional Calculations (2010)
The receiver domain of sensor histidine kinase of CKI1: its dynamic structure and binding specificity. (2010)
Dynamic structure and binding specifity of the receiver domain of sensor histidine kinase CKI1 (2010)
Simulations of 129Xe chemical shift of atomic xenon dissolved in liquid benzene (2010)
NMR,X-ray and DFT investigations of Pt(IV) complexes with aromatic cytokinins (2010)
Interactions between the Nse3 and Nse4 Components of the SMC5-6 Complex Identify Evolutionarily Conserved Interactions between MAGE and EID Families (2011)
Study of RNA polymerase delta subunit unique for gram-positive bacteria (2011)
Complementation of 3D structure of delta subunit of RNA polymerase from Bacillus subtilis with description of internal motions in terms of reduced spectral density mapping (2011)
Crystallization and structure determination of delta-subunit of RNApolymerase (2011)
Simulations of 129 Xe NMR chemical shift of atomic xenon dissolved in liquid benzene (2011)
NMR study of an RNA polymerase subunit unique for gram-positive bacteria (2011)
Structural analysis of delta-subnit of RNA-polymerase by X-ray (2011)
Cloning and expression of endolysin and its SH3b-domain from polyvalent staphylococcal bacteriophage (2011)
NMR and Computational Study of Supramolecular Interactions (2011)
Backbone assignment and secondary structure of the PsbQ protein from Photosystem II (2011)
A new isoflavanone from Iresine herbstii (2011)
Natural Compound Cudraflavone B Shows Promising Anti-inflammatory Properties in Vitro (2011)
Interpretation of substituent effects on 13C and 15N NMR chemical shifts in 6-substituted purines (2011)
Unprecedented pi...pi interaction between an aromatic ring and a pseudo-aromatic ring formed through intramolecular H-bonding in a bidentate Schiff base ligand: crystal structure and DFT calculations (2011)
Novel Adamantane-Bearing Anilines and Properties of Their Supramolecular Complexes with beta-Cyclodextrin (2011)
5D 13C-detected experiments for backbone assignment of unstructured proteins with a very low signal dispersion (2011)
NMR STUDY OF RALSTONIA SOLANACEARUM LECTIN INTERACTIONS (2011)
Simulation of 129Xe NMR chemical shift of Xe@C60 dissolved in liquid benzene (2011)
Cloning, expression and structure determination of SH3b cell wall binding domain of bacteriophage 812 endolysin (2011)
Klonování genů fágových lytických enzymů a jejich funkčních domén (2011)
Redistribution of electron density in pyridinium and pyrazinium guests induced by complexation with cucurbit[6]uril (2011)
NMR cross-correlated relaxation rates reveal ion coordination sites in DNA (2011)
Supramolecular Shuttle Based on Inclusion Complex between Cucurbit[6]uril and Bispyridinium Ethylene (2011)
Structure and binding specificity of the receiver domain of sensor histidine kinase CKI1 from Arabidopsis thaliana. (2011)
The X-ray structure versus NMR structure of delta-subunit of RNA-polymerase (2011)
Molecular Mechanisms of Signalling Specificity via Phosphorelay Pathways in Arabidopsis (2011)
Validation of relativistic DFT approaches to the calculation of NMR chemical shifts in square-planar Pt2+ and Au3+ complexes (2011)
NMR STUDY OF INTERACTIONS OF RALSTONIA SOLANACEARUM LECTIN (2011)
Pavlíková N, Bláhová L, Klán P, Bathula SR, Sklenár V, Giesy JP, Bláha L. Enantioselective effects of alpha-hexachlorocyclohexane (HCH) isomers on androgen receptor activity in vitro. Chemosphere (2011)
Plant aminoaldehyde dehydrogenases oxidize a wide range of nitrogenous heterocyclic aldehydes (2012)
In Silico Engineering of Proteins that Recognize Small Molecules (2012)
CHARACTERIZATION OF THE NSE4/EID BINDING TO NSE3/MAGE PROTEINS (2011)
Vnitřní lékařství (2011)
Platinum-Modified Adenines: Unprecedented Protonation Behavior Revealed by NMR Spectroscopy and Relativistic Density-Functional Theory Calculations (2012)
Engineering the cytokinin-glucoside specificity of the maize beta-D-glucosidase Zm-p60.1 using site-directed random mutagenesis (2012)
NMR, X-ray and relativistic DFT study of Pt (IV) complexes with aromatic cytokinins (2011)
Effect of Mg2+ Binding on the Receiver Domain of the CKI1 Sensory Histidine Kinase from Arabidopsis thaliana (2011)
Enantioselective effects of alpha-hexachlorocyclohexane (HCH) isomers on androgen receptor activity in vitro. (2012)
MOLECULAR INTERVENTIONS OF PEPTIDES AND SMALL MOLECULES: A STRUCTURAL STUDY. (2012)
RNA (2012)
Significant changes between the Xray structure and NMR structure of delta subunit of RNA polymerase (2012)
Biocompatible Xanthine-Quadruplex Scaffold for Ion-Transporting DNA Channels (2012)
NMR study of RNA polymerase delta subunit unique for gram-positive bacteria (2012)
Exploring new 129Xe chemical shift ranges in HXeY compounds: hydrogen more relativistic than xenon (2012)
Understanding the NMR properties and conformational behavior of indole vs. azaindole group in protoberberines: NICS and NCS analysis (2012)
Tautomeric equilibria of substituted pyrazolo[4,3-c]pyrazoles: Synthesis of their possible N-methyl isomers (2012)
Tautomeric equilibria of substituted pyrazolo[4,3-c]pyrazoles: Synthesis of their possible N-methyl isomers (2012)
4D Non-uniformly sampled HCBCACON and (1) J(NC alpha)-selective HCBCANCO experiments for the sequential assignment and chemical shift analysis of intrinsically disordered proteins (2012)
Accurate Reduced Spectral Density Mapping for Analysis of 13C Relaxation Rates (2012)
RALSTONIA SOLANACEARUM LECTIN INTERACTIONS, A NMR STUDY (2012)
NMR STUDY - RALSTONIA SOLANACEARUM LECTIN INTERACTIONS (2012)
SH3b cell wall binding domain of bacteriophage 812 endolysin: Cloning, expression and structure determination (2012)
Interpretation of Crystal Effects on NMR Chemical Shift Tensors: Electron and Shielding Deformation Densities (2013)
Origin of the Conformational Modulation of the 13C NMR Chemical Shift of Methoxy Groups in Aromatic Natural Compounds (2013)
SH3b cell wall binding domain of bacteriophage 812 endolysin (2012)
NMR STUDY OF RALSTONIA SOLANACEARUM LECTIN INTERACTIONS (2011)
NMR Studies of the Receiver Domain of the CKI1 Sensory Histidine Kinase from Arabidopsis thaliana (2012)
Multiple Recognition Motifs in Nucleoporin Nup159 Provide a Stable and Rigid Nup159-Dyn2 Assembly (2013)
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of AHP2, a signal transmitter protein from Arabidopsis thaliana (2013)
Toward Reproducing Sequence Trends in Phosphorus Chemical Shifts for Nucleic Acids by MD/DFT Calculations (2013)
Relativistic NMR shielding effects in heavy element complexes (2013)
A relativistic DFT methodology for calculating the structures and NMR chemical shifts of octahedral platinum and iridium complexes (2013)
A theoretical survey on the D7d [84]fullerene, a fullerene with two heptagon rings (2013)
Adamantane-bearing benzylamines and benzylamides: novel building blocks for supramolecular systems with finely tuned binding properties towards beta-cyclodextrin (2013)
129Xe NMR chemical shift in Xe@C60 calculated at experimental conditions: Essential role of the relativity, dynamics, and explicit solvent (2013)
Influence of the O-phosphorylation of serine, threonine and tyrosine in proteins on the amidic N-15 chemical shielding anisotropy tensors (2013)
Intermolecular Interactions in Crystalline Theobromine as Reflected in Electron Deformation Density and 13C NMR Chemical Shift Tensors (2013)
Structure and NMR properties of 6-substituted-5,6-dihydrobenzo[c]phenanthridine alkaloids (2013)
The Delta Subunit of RNA Polymerase Is Required for Rapid Changes in Gene Expression and Competitive Fitness of the Cell (2013)
Molecular heterogeneity and centrosome-associated genes in multiple myeloma (2013)
Synthesis and Tautomerism of Substituted Pyrazolo[4,3-c]pyrazoles (2013)
Intermediate filament-associated cytolinker plectin 1c destabilizes microtubules in keratinocytes (2013)
Catalytic Oxidation of Aromatic Hydrocarbons by Mono-oxido- alkoxidovanadium(V) Complexes of ONNO Donor Ethylenediamine- bis(phenolate) Ligands (2013)
Nemesis - a molecular modeling package (2013)
Celogenomová sekvence bakterie Pragia fontium 26413 (2013)
Identification of genes encoding phage tail-like bacteriocins in Pragia fontium (2013)
Structural Study of the Partially Disordered Full-Length delta Subunit of RNA Polymerase from Bacillus subtilis (2013)
NMR Determines Transient Structure and Dynamics in the Disordered C-Terminal Domain of WASp Interacting Protein (2013)
Efficient protocol for backbone and side-chain assignments of large, intrinsically disordered proteins: transient secondary structure analysis of 49.2 kDa microtubule associated protein 2c (2013)
CHAP domain of tail-associated protein from phage 812 and its lytic activity against Staphylococcus aureus (2013)
Expression of FGF19 in Human Embryonic Stem Cells (2013)
Context-dependent interpretation of the prognostic value of BRAF and KRAS mutations in colorectal cancer (2013)
All–Metal Aromaticity: Revisiting the Ring Current Model among Transition Metal Clusters (2013)
Monitoring prevalence patogenů Leptospira grippotyphosa a Leptospira pomona, Borrelia burgdorferi sensu lato (Bbsl), Coxiella burnetii a Francisella tularensis se zaměřením na volně žijící hlodavce na vybraných lokalitách ČR (Poodří, Moravský kras, Mohelno) v letech 2010-2012 (2013)
Monitoring prevalence patogenů Leptospira grippotyphosa a Leptospira pomona, Borrelia burgdorferi sensu lato (bbsl), Coxiella burnetii a Francisella tularensis se zaměřením Na volně žijící hlodavce na vybraných lokalitách ČR (Poodří, Moravský kras, Mohelno) v letech 2010-2012 (2013)
Intermolecular CH_O/N H-bonds in the biologically important pairs of natural nucleobases: a thorough quantum-chemical study (2014)
Exploring non-covalent interactions in guanine- and xanthine-based model DNA quadruplex structures: A comprehensive quantum chemical approach (2014)
Structural and energetic properties of the potential HIV-1 reverse transcriptase inhibitors d4A and d4G: a comprehensive theoretical investigation (2014)
X ray vs. NMR structure of the N terminal domain of delta subunit of RNA polymerase (2013)
Potential energy surface and binding energy in the presence of an external electric field: modulation of anion–pi interactions for graphene-based receptors (2014)
The occurrence of Borrelia burgdorferi sensu lato in certain ectoparasites (Mesostigmata, Siphonaptera) of Apodemus flavicollis and Myodes glareolus in chosen localities in the Czech Republic (2013)
Activity of the tick Ixodes ricinus monitored in a suburban park in Brno, Czech Republic, in association with evaluation of selected repellents (2013)
Prediction of relativistic NMR chemical shifts in various heavy transition-metal complexes (2013)
Srovnání laparotomie a laparoskopie při implantaci peritoneální části shuntu v léčbě hydrocefalu (2013)
Mechanism of Spin-Orbit Effects on the Ligand NMR Chemical Shift in Transition-Metal Complexes: Linking NMR to EPR (2014)
Malleability and Versatility of Cytochrome P450 Active Sites Studied by Molecular Simulations (2012)
NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity (2013)
Natural Variation in the Heparan Sulfate Binding Domain of the Eastern Equine Encephalitis Virus E2 Glycoprotein Alters Interactions with Cell Surfaces and Virulence in Mice (2013)
Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer (2014)
Deliberate Attenuation of Chikungunya Virus by Adaptation to Heparan Sulfate-Dependent Infectivity: A Model for Rational Arboviral Vaccine Design (2014)
Dimeric Pd(II) and Pt(II) chloride organometallics with 2-phenylpyridine and their solvolysis in dimethylsulfoxide (2014)
Halogen bonding: Model complexes having dihalogen molecules bound to two nonequivalent electron-rich species. (2014)
Study of the Receiver and Receiver-like Domain Relationship in Cytokinin Receptor of Arabidopsis thaliana (2013)
Spectral density mapping protocols for analysis of molecular motions in disordered proteins (2014)
Nová možnost pro detekci AHP2 proteinu z A. thaliana (2013)
Nová možnost pro detekci AHP3 proteinu z A. thaliana (2013)
Nová možnost pro detekci AHP4 proteinu z A. thaliana (2013)
Nová možnost pro detekci AHP5 proteinu z A. thaliana (2013)
Příprava mAb proti rekombinantí formě OspC Borrelia burgdorferi sensu lato (2013)
High-Resolution Insight into G-Overhang Architecture (2013)
RSL lectin - a complex approach to study carbohydrate-protein interaction (2014)
Toward optimal-resolution NMR of intrinsically disordered proteins (2014)
Origin of the Thermodynamic Stability of the Polymorph IV of Crystalline Barbituric Acid: Evidence from Solid-State NMR and Electron Density Analyses (2014)
The EurOPDX consortium: Sharing patient tumor-derived xenografts for collaborative multicentric preclinical trials. (2013)
Toward a consistent interpretation of the QTAIM: Tortuous link between chemical bonds, interactions and bond/line paths (2014)
Tailoring the Properties of Quadruplex Nucleobases for Biological and Nanomaterial Applications (2014)
Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease (2014)
29th NMR Valtice - Central European NMR Meeting (2014)
Recombinant antibodies for in vivo applications (2014)
Combining ferrocene, thiophene and a boronic acid: a hybrid ligand for reagentless electrochemical sensing of cis-diols (2014)
X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase (2014)
X-ray structures of heteroleptic zinc(II) complexes involving combinations of O,O-dialkyldithiophosphato and bidentate N-donor ligands (2014)
Design of Stereoelectronically Promoted Super Lewis Acids and Unprecedented Chemistry of Their Complexes (2014)
Antibodies against CKI1RD, a receiver domain of the sensor histidine kinase in Arabidopsis thaliana: from antigen preparation to in planta immunolocalization. (2014)
Test of Four Colon Cancer Risk-Scores in Formalin Fixed Paraffin Embedded Microarray Gene Expression Data (2014)
Connecting gene expression subtypes of colorectal cancer (CRC) with cell lines and drug resistance (2013)
Distal and proximal colon cancers differ in terms of molecular, pathological, and clinical features (2014)
Modulating graphene ion-receptor properties under influence of an external electric field. (2014)
Nucleic acid quadruplexes based on 8-halo-9-deazaxanthines: Energetics and non-covalent interactions in quadruplex stems (2014)
Structure-functional study of PHL lectin from Photorhabdus asymbiotica (2014)
Strukturně-funkční studium lektinu PHL z Photorabdus asymbiotica a jeho význam v patogenezi (2014)
Triplex intermediates in folding of human telomeric quadruplexes probed by microsecond-scale molecular dynamics simulations (2014)
Identification of Key Structural Characteristics of Schisandra chinensis Lignans Involved in P-Glycoprotein Inhibition (2014)
Dissection of Binding between a Phosphorylated Tyrosine Hydroxylase Peptide and 14-3-3zéta: A Complex Story Elucidated by NMR (2014)
In-Cell NMR and EPR Spectroscopy of Biomacromolecules (2014)
Functional Analysis of Dishevelled-3 Phosphorylation Identifies Distinct Mechanisms Driven by Casein Kinase 1 epsilon and Frizzled5 (2014)
MECHANISM OF BASE EXCISION WITH THE hOGG1 DNA REPAIR ENZYME (2014)
Robust and highly accurate automatic NOESY assignment and structure determination with Rosetta (2014)
Studying Weak and Dynamic Interactions of Posttranslationally Modified Proteins using Expressed Protein Ligation (2014)
Targeted In Vivo Inhibition of Specific Protein–Protein Interactions Using Recombinant Antibodies (2014)
The significant role of the intermolecular CHMIDLINE HORIZONTAL ELLIPSISO/N hydrogen bonds in governing the biologically important pairs of the DNA and RNA modified bases: a comprehensive theoretical investigation (2015)
Stabilization of the beta-hairpin in Mason-Pfizer monkey virus capsid protein- a critical step for infectivity (2014)
Production of human proteins using well-established and alternative recombinant expression hosts (2014)
Loss of loop adenines alters human telomere d(AG3(TTAG3)3) quadruplex folding (2014)
The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signaling (2014)
Patient-Derived Xenograft Models: An Emerging Platform for Translational Cancer Research (2014)
Sonochemical synthesis of lithium fluoride nano cubic as an active and simple catalyst for thia-Michael addition process: synthesis and structural characterization of beta-aryl-beta-mercapto ketones (2015)
Understanding the electronic factors responsible for ligand spin-orbit NMR shielding in transition-metal complexes (2015)
CHAP domain of tail-associated protein from phage 812 and its lytic activity against Staphylococcus aureus (2014)
Structural Biology in Use : NMR, X-ray and Molecular Dynamics Modeling in Study on Multistep Phosphorelay Signaling in Plants (2014)
Conformational dynamics and antigenicity in the disordered malaria antigen merozoite surface protein 2 (2015)
A Novel Protein-Protein Interaction in the RES (REtention and Splicing) Complex (2014)
The activation of N-glycosidic bond cleavage performed by base-excision repair enzyme hOGG1; theoretical study of the role of Lys 249 residue in activation of G, OxoG and FapyG (2014)
Retro operation on the Trp-cage miniprotein sequence produces an unstructured molecule capable of folding similar to the original only upon 2,2,2-trifluoroethanol addition (2014)
Výzkum a vývoj fágových lytických enzymů pro terapii stafylokokových infekcí 2014 (2014)
Wnt-regulated dynamics of positional information in zebrafish somitogenesis (2014)
A novel panel of proteins correlating with lymph node metastasis of low-grade breast cancer as identified by combined proteomics and transcriptomics approach (2014)
Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex. (2015)
The melanoma-associated antigen 1 (MAGEA1) protein stimulates the E3 ubiquitin-ligase activity of TRIM31 within a TRIM31-MAGEA1-NSE4 complex (2015)
30th NMR Valtice - Central European NMR Meeting (2015)
Designing a New Class of Bases for Nucleic Acid Quadruplexes and Quadruplex-Active Ligands (2015)
Interaction of ferroceneboronic acid with diols at aqueous and non-aqueous conditions - signalling and binding abilities of an electrochemical probe for saccharides (2015)
OspC typy a invazivita Bbsl z lokality Pisárky, Brno. Exprese OspC ve vysoké koncentraci, izolace protilátek proti OspC a epitopové mapování OspC (2015)
Unique C. elegans telomeric overhang structures reveal the evolutionarily conserved properties of telomeric DNA (2015)
Instability restricts signaling of multiple fibroblast growth factors (2015)
A novel variant of FGFR3 causes proportionate short stature (2015)
Trigonal to tetrahedral transitions in Cu(I) six-membered inorganic true heterocycles (2015)
EUROMAR 2015. Programme and Abstract Book (2015)
Structure, solvent, and relativistic effects on the NMR chemical shifts in square-planar transition-metal complexes: assessment of DFT approaches (2015)
Molecular Rods Combining o-Carborane and Bicyclo[1.1.1]pentane Cages: An Insertion of the Triple Bond Located Next to a Highly Strained Cage (2015)
Izolace myších monoklonálních protilátek proti OspC proteinu a identifikace vazebných epitopů (2015)
Substituting CF2 for O4' in Components of Nucleic Acids: Towards Systems with Reduced Propensity to Form Abasic Lesions (2015)
Is NICS a reliable aromaticity index for transition metal clusters? (2015)
Exploring Reaction Pathways for O-GlcNAc Transferase Catalysis. A String Method Study (2015)
Testování účinnosti enzymové terapie na kmenech Staphylococcus aureus (2015)
Endolysin a jeho in vitro aktivita vůči kmenům Staphylococcus aureus izolovaných u popálených pacientů a pacientů s chronickou ranou (2015)
NMR assignment of intrinsically disordered self-processing module of the FrpC protein of Neisseria meningitidis (2015)
Quantum Chemical Benchmark Study on 46 RNA Backbone Families Using a Dinucleotide Unit (2015)
Cell cycle-dependent changes in H3K56ac in human cells. (2015)
Impact of nucleic acid self-alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions (2016)
Cross-correlated relaxation measurements under adiabatic sweeps: determination of local order in proteins (2015)
FGF19/BETA-KLOTHO REGULATE PHYSIOLOGY AND DIFFERENTIATION OF HUMAN PLURIPOTENT STEM CELLS (2014)
Cloning, expression and purification of the human Islet Amyloid Polypeptide (hIAPP) from Escherichia coli (2015)
Frontiers in CryoEM (2014)
The influence of Mg2+ coordination on 13C and 15N chemical shifts in CKI1RD protein domain from experiment and molecular dynamics/density functional theory calculations (2016)
Ceremonial inauguration of the "Josef Dadok National NMR Centre" (2013)
Molecular architecture of the ribosome-bound Hepatitis C Virus internal ribosomal entry site RNA (2015)
Sequence and structural determinants of human APOBEC3H deaminase and anti-HIV-1 activities (2015)
Impact of structural stability of cold adapted Candida antarctica lipase B (CaLB): in relation to pH, chemical and thermal denaturation (2015)
Výzkum a vývoj fágových lytických enzymů pro terapii stafylokokových infekcí (2015)
DNA-based identification and OspC serotyping in cultures of Borrelia burgdorferi s.l. isolated from ticks collected in the Moravia (Czech Republic) (2016)
High-yield expression of OspC protein from B. burgdorferi, isolation of monoclonal antibodies and epitope mapping (2016)
Spectral density mapping at multiple magnetic fields suitable for C-13 NMR relaxation studies (2016)
Evolution of the NSE1-NSE3-NSE4 subcomplex of the human SMC5/6 complex (2015)
Structural Aspects of Multistep Phosphorelay-Mediated Signaling in Plants (2016)
Expression, purification and crystallization of the intracellular domains of the ethylene receptor ETR1 from Arabidopsis thaliana (2015)
STUDIUM INTRACELULÁRNÍCH DOMÉN ETYLÉNOVÉHO RECEPTORU ETR1 (2016)
Cystatins of helminths: characterization of molecules with immunomodulatory potential (2016)
ROLE OF IN VITRO PHOSPHORYLATION ASSAY IN UNDERSTADING MSP SIGNALING IN A. THALIANA (2016)
The Eighth Central European Conference “Chemistry towards Biology”: Snapshot (2016)
Eudiplozoon nipponicum (Heteronchoinea: Diplozoidae): insight into composition of E/S products and basic characterization of serpin (2016)
Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins (2016)
Molecular and biochemical characterization of cysteine peptidase inhibitor from Eudiplozoon nipponicum (Monogenea) (2016)
Structural Characterization of the Extracellular Domain of CASPR2 and Insights into Its Association with the Novel Ligand Contactin1 (2016)
E. coli metabolic protein aldehyde-alcohol dehydrogenase-E binds to the ribosome: a unique moonlighting action revealed (2016)
Výzkumný plán pro rekombinantní expresi proteas v produkční bakterii Escherichia coli s využitím technologie syntetických genů (2016)
Deveopment of a microfluidic specimenpreparation device for time-resolved cryo-electron microscopy (2016)
Epitope mapping of Borrelia burgdorferi OspC protein in homodimeric fold (2017)
SERPIN, A KEY MOLECULE IN THE LIFE OF EUDIPLOZOON NIPPONICUM?! (2017)
Phosphorylation of the regulatory domain of human tyrosine hydroxylase 1 monitored using non-uniformly sampled NMR (2017)
Quantitative mapping of microtubule-associated protein 2c (MAP2c) phosphorylation and regulatory protein 14-3-3 zeta-binding sites reveals key differences between MAP2c and its homolog Tau (2017)
Solution structure of domain 1.1 of the sigma(A) factor from Bacillus subtilis is preformed for binding to the RNA polymerase core (2017)
Conformational dynamics are a key factor in signaling mediated by the receiver domain of a sensor histidine kinase from Arabidopsis thaliana (2017)
Conformational Entropy from Slowly Relaxing Local Structure Analysis of N-15-H Relaxation in Proteins: Application to Pheromone Binding to MUP-I in the 283-308 K Temperature Range (2017)
Tau tubulin kinase 2 phosphorylations in cilia initiation (2017)
Modulation of melanoma metabolism and viability with hexokinase and mitochondrial complex I inhibitors (2014)
Triple resonance NMR relaxation experiments for studies of intrinsically disordered proteins (2017)
Exploring the binding pathways of the 14-3-3 zeta : protein Structural and free-energy profiles revealed by Hamiltonian replica exchange molecular dynamics with distancefield distance restraints (2017)
Free energy calculations on the stability of the 14-3-3 zeta protein (2018)
NMR characterization of intrinsically disordered microtubule associated protein 2c (2017)
Computational characterization of hybrid proteins containing ordered and intrinsically disordered regions (2017)
Role of SH3b binding domain in a natural deletion mutant of Kayvirus endolysin LysF1 with a broad range of lytic activity (2018)
CIISB Kick-off Meeting (2016)
Den otevřených dvěří pro veřejnost (2016)
Exkurze talentovaných SŠ studentů (2016)
Open day for MU students (2016)
AFM a nanobiotechnologie (2016)
Functionally specific binding regions of microtubule-associated protein 2c exhibit distinct conformations and dynamics (2018)
Conformation and dynamics of intrinsically disordered microtubule associated protein 2c (2018)
Nuclear Magnetic Resonance (2018)
Computational Molecular Modeling Techniques of Biomacromolecular Systems (2018)
Protein environment affects the water-tryptophan binding mode. MD, QM/MM, and NMR studies of engrailed homeodomain mutants (2018)
High-Resolution NMR of Folded Proteins in Hyperpolarized Physiological Solvents (2018)
Time-Resolved Protein Side-Chain Motions Unraveled by High-Resolution Relaxometry and Molecular Dynamics Simulations (2018)
Kit pro screening potenciálních léčiv indukujících monomerizaci 14-3-3 (2018)
Structure and Functions of Microtubule Associated Proteins Tau and MAP2c: Similarities and Differences (2019)
Understanding the methyl-TROSY effect over a wide range of magnetic fields (2019)
Quantum Chemical Calculations of NMR Chemical Shifts in Phosphorylated Intrinsically Disordered Proteins (2019)
Structural study of 14-3-3ζ monomeric mutant. (2019)
Determination of the dimer-monomer equilibrium of 14-3-3ζ protein. (2017)
Thermodynamic and kinetic study of 14-3-3ζ dimerization (2017)
Monomer-dimer equilibria of 14-3-3ζ protein. (2019)
Quantitative Conformational Analysis of Functionally Important Electrostatic Interactions in the Intrinsically Disordered Region of Delta Subunit of Bacterial RNA Polymerase (2019)
Protein Dynamics from Accurate Low-Field Site-Specific Longitudinal and Transverse Nuclear Spin Relaxation (2019)
Choice of Force Field for Proteins Containing Structured and Intrinsically Disordered Regions (2020)
Boosting the resolution of low-field 15N relaxation experiments on intrinsically disordered proteins with triple-resonance NMR (2020)
Sensitivity-enhanced three-dimensional and carbon-detected two-dimensional NMR of proteins using hyperpolarized water (2020)
Structural Basis of Ca2+-Dependent Self-Processing Activity of Repeat-in-Toxin Proteins (2020)
Evaluation of Physiological Parameters of Intestinal Sulfate-Reducing Bacteria Isolated from Patients Suffering from IBD and Healthy People (2020)
DESIGNING RECOMBINANT MAIZE beta-GLUCOSIDASE Zm-p60.1: DEVELOPMENT OF NOVEL ENZYMES MODULATING CYTOKININ METABOLISM (2010)
OXIDATION SIGNALS OF INSULIN ON SCREEN-PRINTED ELECTRODES (2020)
Phosphomimicking mutants: why to be careful (2020)
Quadruplex Priming Amplification at a Range of Human Body Temperature (2021)
OPTIMIZATION OF EXPRESSSION AND PURIFICATION OF FRAGMENT FROM TAU PROTEIN (2020)
CHALLENGES IN STRUCTURAL AND INTERACTION PROPERTIES OF INTRINSICALLY DISORDERED PROTEINS (2020)
HOW PHOSPHORYLATION IMPACTS 14-3-3ζ DIMERIZATION (2020)
Importance of base-pair opening for mismatch recognition (2020)
Basic Bioelement Contents in Anaerobic Intestinal Sulfate-Reducing Bacteria (2021)
Binding and inhibitory effect of ravidasvir on 3CLpro of SARS-CoV-2: a molecular docking, molecular dynamics and MM/PBSA approach (2022)
Study of Conformational and Dynamic Changes upon Phosphorylation of Proline Rich Region of Tau210-240 Peptide Using Molecular Dynamic Simulation (2021)
Theoretical and computational framework for the analysis of the relaxation properties of arbitrary spin systems. Application to high-resolution relaxometry (2020)
Virion structures and genome delivery of honeybee viruses (2020)
Studying Tight Dimers Using Ordinary Fluorimeter (2020)
Polyethylene glycol perturbs the unfolding of CRABP I: A correlation between experimental and theoretical approach (2021)
Investigation of the structure and dynamics of gallium binding to high-affinity peptides elucidated by multi-scale simulation, quantum chemistry, NMR and ITC dagger (2021)
Capsid opening enables genome release of iflaviruses. (2021)
Internet a výuka chemie (2011)
An in silico molecular dynamics simulation study on the inhibitors of SARS-CoV-2 proteases (3CLpro and PLpro) to combat COVID-19 (2021)
Perturbing the unfolding of CRABP I using polyethylene glycol: An experimental and theoretical study (2021)
Universal two-point interaction of mediator KIX with 9aaTAD activation domains (2021)
19F labelling of 14-3-3ζ recombinant protein for 19F NMR spectroscopy (2021)
Cysteine Modification by Ebselen Reduces the Stability and Cellular Levels of 14-3-3 Proteins (2021)
Detection of Metabolite-Protein Interactions in Complex Biological Samples by High-Resolution Relaxometry: Toward Interactomics by NMR (2021)
Molecular dynamics simulation of protein and protein-ligand complex (2021)
Cargo Release from Nonenveloped Viruses and Virus-like Nanoparticles: Capsid Rupture or Pore Formation (2021)
NMR Studies of Tau Protein in Tauopathies (2021)
14-3-3ζ phosphomimicking mutants: an alternative to phosphorylation? (2021)
Quantitation of Human 14-3-3ζ Dimerization and the Effect of Phosphorylation on Dimer-monomer Equilibria (2022)
Phosphorylated and Phosphomimicking Variants May Differ—A Case Study of 14-3-3 Protein (2022)
Impact of Chromate and Dichromate on Lysozyme Stability: A Spectroscopic and Molecular Docking Investigation (2022)
Biophysical characterisation of phosphorylated 14-3-3ζ protein (2021)
Phosphomimicking mutations ≠ phosphorylation - a case study of 14-3-3 protein (2022)
19F labelling of disordered and hybrid proteins for 19F NMR spectroscopy (2022)
Metagenomic research of the ancient human dental calculus as a potential source for the study of rare infectious diseases (2022)
Multiple approaches for protein phosphorylation: a story of 14-3-3 (2022)
19F Trp labelling as a selective probe into the dimeric interface (2022)
Microbial Communities in Underground Gas Reservoirs Offer Promising Biotechnological Potential (2022)
NMR Provides Unique Insight into the Functional Dynamics and Interactions of Intrinsically Disordered Proteins (2022)
Describing 14-3-3 dimerization: tools to obtain KD (2022)
Impact of Phosphorylation for Tau210-240 Peptide and Interaction of Small Molecules and 14-3-3ζ Protein Studies Using Computational Methods (2022)
Toward protein NMR at physiological concentrations by hyperpolarized water-Finding and mapping uncharted conformational spaces (2022)
Calculation of NMR spin-spin couplings for intrinsically disordered proteins: a prospective tool to facilitate experimental NMR studies (2021)
Multiscale NMR calculations of spin-spin couplings and the phophprylation induced chemical shifts changes in disordered proteins (2022)
Specific phosphorylation of microtubule-associated protein 2c by extracellular signal–regulated kinase reduces interactions at its Pro-rich regions (2022)
Computational approach for building QSAR models for inhibition of HIF-1A (2022)
From nano- to milimolar: dimerization dissociation constant determination (2022)
Biophysical characterization of extracellular carbonic anhydrase IX (2022)
Biomolecular Complexation on the "Wrong Side": A Case Study of the Influence of Salts and Sugars on the Interactions between Bovine Serum Albumin and Sodium Polystyrene Sulfonate (2022)
A new fibrillization mechanism of β-lactoglobulin in glycine solutions (2022)
Convergent views on disordered protein dynamics from NMR and computational approaches (2022)
Seeing the invisible – Study of transiently formed protein conformation found in domain 1.1 of bacterial transcription factor (2022)
Interactions of adaptor protein Grb2 with microtubule associated protein 2c (2022)
Structure of recombinant Tau40 protein fibrils prepared without enhancers of fibrilization (2022)
Kolaterálna cirkulácia zlepšuje rekanalizáciu pôsobením alteplázy: in vitro štúdia (2022)
Human myelin proteolipid protein structure and lipid bilayer stacking (2022)
Honeybee Iflaviruses Pack Specific tRNA Fragments from Host Cells in Their Virions (2022)
Interaction of selected drugs at dimer interface of human 14-3-3ζ protein (2023)
Designing of Insecticides Against Bemisia tabaci targeting ecdysone receptor (2023)
Conformational changes upon phosphorylation of proline rich region of tau(210-240) peptide using molecular dynamic simulation (2023)
To homodimerize or to heterodimerize: story of 14-3-3 protein dimer formation (2022)
14-3-3 protein isoforms: mutual dimerization propensities screening kit (2022)
Molecular dynamic simulation study of multiple phosphorylations at the proline rich region of tau(210-240) peptide (2023)
Preparation of catalytic domain of carbonic anhydrase IX with different protein tags (2022)
Novel Förster Resonance Energy Transfer probe with quantum dot for a long-time imaging of active caspases inside individual cells (2023)
Domain 1.1 of σA factor of RNA polymerase from Bacillus subtilis beyond its major state conformation (2023)
Pathological tau protein fibrils – structure and cellular context (2023)
Characterization of a transitionally occupied state and thermal unfolding of domain 1.1 of σ A factor of RNA polymerase from Bacillus subtilis (2023)
Conformation and Affinity Modulations by Multiple Phosphorylation Occurring in the BIN1 SH3 Domain Binding Site of the Tau Protein Proline-Rich Region (2023)
Employment of 5D non-uniform sampling NMR assignment strategy to assign disordered protein regions with repetitive motifs (2023)
Characterisation of invisible conformation of domain 1.1 of σA factor of RNA polymerase from Bacillus subtilis (2023)
14-3-3 dimer vs monomer – (dis)similarities in Tau protein binding (2023)
Study of conformational changes of Tau(210-240) upon multiple phosphorylations using molecular dynamics simulations (2023)
Levodopa may modulate specific speech impairment in Parkinson's disease: an fMRI study (2024)
Recognition and coacervation of G-quadruplexes by a multifunctional disordered region in RECQ4 helicase (2023)
Quaternary Benzophenanthridine Alkaloids Act as Smac Mimetics and Overcome Resistance to Apoptosis (2023)
Detailed insight into dynamics of C-terminal domain of δ subunit of RNA polymerase from Bacillus subtilis using high-resolution relaxometry (2023)
Detailed insight into dynamics of intrinsically disordered proteins using high-resolution relaxometry (2023)
Study of the Dynamics of Flexible Subunits of RNA Polymerase from Bacillus subtilis (2023)
Tale of tails; structural comparison of the RNA polymerase δ-subunits (2024)
Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models (2024)
Hiding in plain sight: Complex interaction patterns between Tau and 14-3-3zeta protein variants (2024)
The effect of phosphoserine 324 on the paired helical filaments of tau protein (2024)
How does phosphorylation affect interaction between 14-3-3ζ and Tau proteins? (2024)
Preparation of Alzheimer's-disease-relevant Tau protein in HEK293 mammalian cells (2024)
The interplay of δ-subunit and RNA polymerase in the pre-initiation state (2024)
NOVEL INHIBITORS OF HUMAN CARBONIC ANHYDRASE (2024)
dGAE(297-391) Tau Fragment Promotes Formation of Chronic Traumatic Encephalopathy-Like Tau Filaments (2024)

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