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Vybrané publikace/výsledky

Surface plasmon resonance and carbohydrate-lectin interactions (2009)
Construction of mutant lectins from Chromobacterium violaceum and study of changes in their binding properties (2009)
Changes of binding specificity and thermodynamical parameters of lectin from Chromobacterium violaceum - carbohydrate binding site mutagenesis in the position 97 (2009)
Lectin from Chromobacterium violaceum - role of water molecule in the carbohydrate binding site (2010)
Thermodynamics behind CV-IIL binding of saccharides (2011)
Expression of hypothetical lectin from pisum sativum-comparison of two eukaryotic expression systems (2012)
Influence of targeted amino acid substitution on specificity and affinity of lectins from pathogenic bacteria (2012)
MotiveValidator: interactive web-based validation of ligand and residue structure in biomolecular complexes (2014)
New family of bacterial lectins with seven bladed beta propeller fold (2014)
X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase (2014)
Structure-functional study of PHL lectin from Photorhabdus asymbiotica (2014)
Strukturně-funkční studium lektinu PHL z Photorabdus asymbiotica a jeho význam v patogenezi (2014)
ValidatorDB: database of up-to-date validation results for ligands and non-standard residues from the Protein Data Bank (2015)
Mutagenéza lektínu AFL ako nástroj pre štúdium komplexných interakcií lektín-sacharid (2014)
MotiveValidator: software for validation of ligand and residue structures in biomolecular complexes (2014)
ValidatorDB: database of validation results for ligands and non-standard residues from the Protein Data Bank (2014)
Burkholderia cenocepacia lectins and their native ligands (2014)
Self-assembled, 1,2-thiomannobioside contaning glycoconjugates as potent ligand of Burkholderia cenocepacia lectins (2014)
Studies of mutant lectin binding behaviour by microcalorimetry (2014)
Recombinant Lectin from insect pathogen Photorhabdus luminisnce: structural and functional studies (2014)
Homology modeling of human intelectin-1 (2014)
Targeted-random mutagenesis of PA-IIL lectin and high-throughput screening of mutant library (2014)
Analytical techniques in the functional and structural studies of lectin-sugar interaction (2014)
Differences among binding sites of AAL family lectins - High affinity vs. high specificity of sugar binding (2014)
Combination of methods is always useful - Aspergillus fumigatus lectin AFL as a case study (2014)
Crystallization and functional studies of trimeric lectin RS20L from bacterium Ralstonia solanacearum (2014)
Structural studies of mycobacterial glycosyltransferase GlfT1 (2014)
Possibilities for biomacromolecular crystallization at BIC Core Facility at CEITEC, Brno (2015)
XVI. Setkání biochemiků a molekulárních biologů : Sborník příspěvků (2014)
Structural insights into Aspergillus fumigatus lectin specificity: AFL binding sites are functionally non-equivalent (2015)
Structure and specificity of lectin from bacterium Burkholderia pseudomallei (2015)
One point mutation can overturn sugar-binding specificity of lectin RS-IIL from plant pathogen Ralstonia solanacearum (2015)
Hemagglutination as a tool for lectins characterization (2015)
Synthesis of glycodendrimers containing 1,2-thiomannobioside and investigation of their interaction with BC2L-A lectin from Burkholderia cenocepacia (2015)
EXPRESSION AND CRYSTALLIZATION OF MYCOBACTERIAL GALACTOFURANOSYL TRANSFERASE GLFT1 (2015)
A point mutation led to overturn in sugar-binding specificity of lectin RS-IIL from PA-IIL lectin superfamily (2015)
XVII. Setkání biochemiků a molekulárních biologů : sborník příspěvků (2015)
Photorhabdus asymbiotica lectins: structure and function of putative virulence factors (2015)
Newly identified lectin from Photorhabdus asymbiotica and its structure-functional study (2014)
Study of PHL lectin from Photorabdus asymbiotica to revealing its role in pathogenesis (2015)
Lectins with beta-propeller fold in opportunistic pathogens (2016)
Current State-of-Art to Study Biomolecular Interactions and Assemblies in Life Sciences (2014)
Fluorescent Cellular Assay for Screening Agents Inhibiting Pseudomonas aeruginosa Adherence (2015)
Evaluation of anti-PAIIL lectin hen yolk antibody as an agent inhibiting Pseudomonasaeruginosa adherence to epithelial cells (2016)
FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection (2016)
Multivalent Carbohydrate-based Inhibitors of Lectins (2016)
Characterization of lectins from Photorhabdus luminescens to reveal their function in entomopathogenic complex with Heterorhabditis bacteriophora (2016)
Expression, purification and crystallization of the intracellular domains of the ethylene receptor ETR1 from Arabidopsis thaliana (2015)
STUDIUM INTRACELULÁRNÍCH DOMÉN ETYLÉNOVÉHO RECEPTORU ETR1 (2016)
Structure and function of Photorhabdus asymbiotica lectins: Studies of potential virulence factors from emerging human pathogen (2016)
Structural and functional determination of predicted core fucose specific mutants of Ralstonia solanacearum lectin (2016)
A Novel Fucose-Binding Lectin from Photorhabdus luminescens (PLL) with an Unusual Heptabladed beta-Propeller Tetrameric Structure (2016)
New lectin from insect pathogen Photorhabdus luminiscence: structural and functional studies (2015)
Step-by-Step In Vitro Mutagenesis: Lessons From Fucose-Binding Lectin PA-IIL (2017)
Tri- and tetravalent mannoclusters cross-link and aggregate BC2L-A lectin from Burkholderia cenocepacia (2017)
Development and application of a novel recombinant Aleuria aurantia lectin with enhanced core fucose binding for identification of glycoprotein biomarkers of hepatocellular carcinoma (2016)
Glycobiochemistry: from bugs to cystic fibrosis (2017)
Characterization of lectin AFL from opportunistic pathogen Aspergillus fumigatus – combining a broad spectrum of biophysical methods (2017)
Carbohydrate-based inhibitors of lectins from pathogenic microorganisms (2017)
Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity (2017)
Synthesis of a-L-fucopyranosidecontaining tri- and tetravalent glycodendrons as high affinity ligands of recombinant Photorhabdus asymbiotica lectin (rPHL) (2017)
Novel bangle lectin from Photorhabdus asymbiotica: sugar-binding specificity, structure and interaction with host immune system (2017)
Conformational dynamics are a key factor in signaling mediated by the receiver domain of a sensor histidine kinase from Arabidopsis thaliana (2017)
Dirigent proteins in plants: modulating cell wall metabolism during abiotic and biotic stress exposure (2017)
Study of Photorhabdus luminescens lectins to reveal their function in entomopathogenic life cycle (2017)
Newly identified bangle lectin from Photorhabdus asymbiotica and its role in pathogenesis (2017)
Synthesis of a-L-fucopyranoside-presenting glycoclusters and investigation of their interaction with recombinant Photorhabdus asymbiotica lectin (PHL) (2018)
Structure and properties of heavy-metal binding protein from Agaricus bisporus. A case study on utilizing X-ray crystallography and different biophysical techniques for elucidating protein function (2017)
Multivalent inhibitors of lectins from pathogenic microorganisms (2017)
Crystallization and stability studies of trimeric lectin RS20L from phytopathogen Ralstonia solanacearum (2017)
CH-pi stacking interaction in carbohydrate-protein complexes (2017)
Validation and analyses of biomacromolecular ligand conformations (2017)
Influence of Trp flipping on carbohydrate binding in lectins. An example on Aleuria aurantia lectin AAL (2017)
Looking for inhibitor: structural and functional analysis of novel bangle lectin PHL from Photorhabdus asymbiotica (2018)
Methods of biochemical research (2016)
MST Lecture & Consultation (2017)
Biological role of PLL and PHL – lectins produced by entomopathogenic bacteria Photorhabdus luminescens and Photorhabdus asymbiotica (2018)
Terminology of bioanalytical methods (IUPAC Recommendations 2018) (2018)
RS20L protein from bacterium Ralstonia solanacearum : Studies of lectin activity and oligomerization (2018)
Carbohydrate-based multivalent inhibitors of lectins from pathogenic microorganisms (2018)
Lectin RS20L from plant pathogen Ralstonia solanacearum : Stability studies and crystallization (2018)
Carbohydrate-protein complexes with CH-pi stacking interaction (2018)
Contribution of CH-pi stacking interaction to carbohydrate-protein complexes (2018)
Importance of CH-pi stacking interaction in carbohydrate-protein complexes (2018)
Structural comparison of lectins from Photorhabdus spp (2018)
Study of lectins from Photorhabdus luminescens bacterium (2018)
Glycoclusters as tool for inhibiton of lectin mediated bacterial adhesion (2018)
Selectivity of original C-hexopyranosyl calix[4]arene conjugates towards lectins of different origin (2018)
AB21, a protein of unknown function from Agaricus bisporus. A case study on utilizing experimental and bioinformatical approaches for functional assignment of unknown proteins (2018)
Characterization of PluLec, a novel galactose-specific lectin from Photorhabdus luminescens (2018)
Carbohydrate-protein binding site interaction (2018)
Allostery in the human Hsp70 chaperone protein. (2018)
Structure and properties of AB21, a novel Agaricus bisporus protein with structural relation to bacterial pore-forming toxins (2018)
Synthesis of ß-D-galactopyranoside-presenting glycoclusters and investigation of their interactions with Pseudomonas aeruginosa lectin A (PA-IL) (2019)
Cytokinin and Ethylene Signaling (2018)
Study of lectins from opportunistic pathogens and their interaction with normal human cells. (2019)
Isolation and characterization of potential lectin from Adenanthera pavonina seeds (2018)
Isolation and characterization of new ricin-B-like lectin from champignon mushroom (2018)
Plant immune response of tabacco cells to RSL lectin from Ralstonia solanacearum (2018)
Comparative structural analysis of lectin family from Photorhabdus spp. (2019)
Structure-functional study of lectins: key players in a fight between host and pathogen (2019)
Microbe-focused glycan array screening platform (2019)
Infulence of glucose 3-O-methylation on binding properties towards PLL2 lectin (2019)
Summer School on New Approaches in Experimental Biology (2018)
SPR workshop - Applications in life-science (2018)
Investigation of the Binding Affinity of a Broad Array of L-Fucosides with Six Fucose-Specific Lectins of Bacterial and Fungal Origin (2019)
HSPA1A conformational mutants reveal a conserved allosteric pathway in Hsp70 proteins (2019)
Photorhabdus lectins disrupt the activity of insect and human immune system (2019)
Microscopy examination of red blood and yeast cell agglutination induced by bacterial lectins (2019)
Differences in binding of D-glucose and 3-O-methyl-D-glucose towards lectin PLL2 (2019)
Fucosylated inhibitors of recently identified bangle lectin from Photorhabdus asymbiotica (2019)
Comparative structural analysis of lectin family from Photorhabdus spp. (2019)
What is written is not always given: Errors in articles (and not only there) (2019)
Synthesis of beta-D-galactopyranoside-Presenting Glycoclusters, Investigation of Their Interactions with Pseudomonas aeruginosa Lectin A (PA-IL) and Evaluation of Their Anti-Adhesion Potential (2019)
Lectin PLL3, a Novel Monomeric Member of the Seven-Bladed beta-Propeller Lectin Family (2019)
Lectins from human pathogenic bacterium Photorhabdus asymbiotica (2019)
Characterization of novel lectin PLL3 from Photorhabdus laumondii with a seven bladed beta propeller monomeric structure (2019)
Production and characterization of galactose-specific lectin PluLec from plant pathogen Photorhabdus luminescens (2019)
Architecture and Evolution of Blade Assembly in beta-propeller Lectins (2019)
Interactions of carbohydrate and aromatic amino acid in protein binding sites (2019)
Characterization of novel lectins from Burkholderia pseudomallei and Chromobacterium violaceum with seven-bladed beta-propeller fold (2020)
Newly identified DNA methyltransferases of Ixodes ricinus ticks (2020)
Effect of RSL lectin from phytopathogen Ralstonia solanacearum on tabacco plant immune system (2019)
HSPA1A conformational mutants reveal a conserved structural unit in Hsp70 proteins (2020)
Methods for biomolecular interaction analysis at BIC Core Facility, CEITEC MU (2020)
Staufen1 reads out structure and sequence features in ARF1 dsRNA for target recognition (2019)
NanoTemper Technologies Symposium & Workshop (2019)
Study of lectins from Photorhabdus luminescens to reveal their function in P. luminescens life cycle (2016)
XX. setkání biochemiků a molekulárních biologů. Sborník příspěvků. 12.–13. listopadu 2019 (2019)
Effect of anti-PAIIl antibody on Pseudomonas aeruginosa infection in cellular and animal models (2016)
Enzymatic desialylation of lung epithelium increases binding of lectin PAIIL, Pseudomonas aeruginosa virulence factor (2018)
Heptabladed b-propeller lectins PLL2 and PHL from Photorhabdus spp. recognize O-methylated sugars and influence the host immune system (2021)
Staufen1 reads out structure and sequence features in ARF1 dsRNA for target recognition (2020)
The CH-pi Interaction in Protein-Carbohydrate Binding: Bioinformatics and In Vitro Quantification (2020)
Cancer-Associated Substitutions in RNA Recognition Motifs of PUF60 and U2AF65 Reveal Residues Required for Correct Folding and 3 ' Splice-Site Selection (2020)
Synthesis of Tetravalent Thio- and Selenogalactoside-Presenting Galactoclusters and Their Interactions with Bacterial Lectin PA-IL from Pseudomonas aeruginosa (2021)
Instruct-ERIC and ARBRE-MOBIEU Workshop: Analysis and Optimization of Sample Quality for Cryo-electron Microscopy and Other Structural Techniques (2020)
Development of 48-condition buffer screen for protein stability assessment (2021)
Universal two-point interaction of mediator KIX with 9aaTAD activation domains (2021)
Characterization of monomeric lectin PLL3 from Photorhabdus laumondii (2021)
Structural characterization of seven-bladed beta-propeller lectin family from Photorhabdus laumondii (2021)
PLL-like lectin family from entomopathogenic bacterium Photorhabdus laumondii (2021)
Visualization of hydrogen atoms in a perdeuterated lectin-fucose complex reveals key details of protein-carbohydrate interactions (2021)
Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study (2021)
Crucial factors governing the electrochemical impedance on protein-modified surfaces (2021)
Phosphorylated and Phosphomimicking Variants May Differ—A Case Study of 14-3-3 Protein (2022)
The analysis of CH–π interaction in protein–carbohydrate binding (2021)
Business Research Forum (2021)
An introduction to MMS (2021)
CF Day (2021)
Detailed analysis of binding sites in the PLL family (2022)
Methods for characterization of biomolecules at BIC Core facility, CEITEC MU (2022)
Studying the role of PLLs, the family of lectins produced by Photorhabdus sp., the bacterial symbiont of entomopathogenic nematodes (2022)
Dějiny psané přírodovědci : Vývoj vědních oborů na Přírodovědecké fakultě Masarykovy univerzity (2022)
XXI. setkání biochemiků a molekulárních biologů. Sborník příspěvků. 12.–13. listopadu 2019 (2022)
Seven-bladed beta-propeller lectins from entomopathogenic bacterium Photorhabdus laumondii (2022)
Combination of biophysical techniques for protein characterization – a case study of Aspergillus fumigatus lectin (2020)
Establishing of ARBRE – Association of Resources for Biophysical Research in Europe (2021)
Development of 48-condition buffer screen for protein stability assessment (2021)
Novel buffer screen for biomolecular characterization (2022)
Technologies for drug discovery at CEITEC Biomolecular Interactions and Crystallization CF (2022)
Methods for Characterization of Biomolecular Interactions: Classical versus modern (2022)
CF Day Meeting (2022)
New "Blood" in Lectin Research (2021)
Searching for New Lectins in Mushrooms (2022)
The NFkB activation domain is 14-amino-acid-long variant of the 9aaTAD (2023)
Development of lectin arrays for mapping the glycosylation changes in proteins and cells (2022)
Targeting undruggable oncoproteins c-Myc and N-Myc by the 9aaTADs (2023)
Dějiny psané přírodovědci : Vývoj vědních oborů na Přírodovědecké fakultě Masarykovy univerzity (2022)
Dual specificity of PLL2 lectin (2023)
Characterization of a novel lectin from pathogenic fungus Microsporum canis (2022)
Flipping hosts in hyperfine fields of paramagnetic guests (2023)
Bioanalytical Chemistry (2023)
Development of lectin arrays for mapping the glycosylations of proteins and cells (2023)
Production of lectins for lectin arrays (2023)
XXII. setkání biochemiků a molekulárních biologů. Sborník příspěvků (2023)
Amphiphilic Sialic Acid Derivatives as Potential Dual-Specific Inhibitors of Influenza Hemagglutinin and Neuraminidase (2023)
Novel C-type lectin from Ixodes ricinus: a three-domain mystery (2023)
Structural characterization of the jacalin-related lectin from the mushroom Calocera viscosa (2023)
Novel two-domain lectin from bacterium Photorhabdus laumondii (2023)
Zero-field splitting in tetracoordinate Co(II) complexes containing heterocyclic aromatic ligands (2024)
pH-Dependent oligomerisation of γ-conglutin: A key element to understand its molecular mechanism of action (2024)
Evolutionarily conserved cysteines in plant cytosolic seryl-tRNA synthetase are important for its resistance to oxidation (2023)
In vitro biological activity of cobalt(II) complexes with salicylaldimine ligands in microbial and cancer cells (2023)
Benchmarking in biophysics: Insight from the ARBRE society (2023)
ARBRE–Association of Resources for Biophysical Research in Europe (2023)
CEITEC: project-based financing of core facilities (2023)
ARBRE – Association of Resources for Biophysical Research in Europe (2023)
Production of recombinant lectin PluLec from Photorhabdus luminescens for neutron crystallography and its structure-functional characterization. (2023)
Bio-SAXS Practical Course 2023 (2023)
Production and characterization of two-domain lectins from Photorhabdus spp. (2023)
Methods for Characterization of Biomolecular Interactions (2023)
Crystallography Loops: Handling and Maintenance (2023)
CalScreener Workshop: Calorimetric instrument to measure the metabolic response in biological systems (2023)
Novel Drug Discovery & Delivery systems: Malvern Panalytical Biophysical Characterisation Seminar (2023)
Biophysical Screening Workshop & Dianthus hands-on (2023)
TechWatch series: Differential scanning fluorimetry demo (2023)
TechWatch series: Mass photometry workshop: Demonstration of instrument for molecular size analysis (2023)
Myc 9aaTAD activation domain binds to mediator of transcription with superior high affinity (2024)

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