BHBB011s Cell biology and genetics - seminar

Faculty of Medicine
autumn 2024
Extent and Intensity
0/2/0. 2 credit(s). Type of Completion: k (colloquium).
Teacher(s)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (lecturer)
Mgr. Kateřina Francová, Ph.D. (lecturer)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
Mgr. Kateřina Straková, Ph.D. (lecturer)
Jana Růžičková (assistant)
Guaranteed by
prof. MUDr. Iva Slaninová, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Francová, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Tue 10:00–11:40 A18/205
Prerequisites
Knowledge of high-school biology on the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/overview/overview_CZ.qwarp) or similar.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.

The capacity limit for the course is 30 student(s).
Current registration and enrolment status: enrolled: 17/30, only registered: 0/30
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- understanding the chemical composition, structure and properties of the main cellular components
- understanding the basic processes in the cell; and understanding the principles of pathology of these processes in cancer and genetic diseases
- understanding the basic principles of heredity
- understanding the basic methods of molecular diagnostics, gene engineering, gene therapy, use of stem cells
Learning outcomes
After completing the course, the student will be able to:
- Describe the composition, structure and functions of prokaryotic and eukaryotic cells
- Explain the principles of intercellular communication and cell differentiation
- Explain the principles of regulation and purpose of cell division (mitosis and meiosis)
- Explain basic principles of heredity and nature of human genetic diseases
- Describe basic methods of molecular diagnostics
- Explain the principles of tumour transformation
- Describe the basic approaches of gene engineering, gene therapy, stem cells therapy
Syllabus
  • Week 1: Introduction. Basic properties of living systems. Biopolymers. Proteins and their functions
  • Week 2: Bacteria and viruses. Human microbiome
  • Week 3: Structure and functions of eukaryotic cells
  • Week 4: Cytoskeletal system and principles of cells organisation in tissues
  • Week 5: Structure of chromosomes. DNA replication. Human genome
  • Week 6: From gene to protein - the expression of genetic information
  • Week 7: DNA damage and DNA repair. Cell death
  • Week 8: Cell signalling and differentiation
  • Week 9: Cell cycle and mitosis
  • Week 10: Meiosis and gametogenesis. Karyotype, chromosomal aberrations
  • Week 11: Principles of heredity - genes and gene mutations
  • Week 12: Multifactorial inheritance. Molecular diagnostics and basic methods of molecular biology
  • Week 13: Malignant transformation of cells. Cancer
  • Week 14: Basics of gene engineering and gene therapy. Stem cells
Literature
Teaching methods
two-hour seminar per week. The seminar attendance is mandatory.
Assessment methods
Attendance at all seminars is mandatory. An absence must be excused at the Office for Studies within 5 days from the beginning of the absence. In the case of unexcused absence, the course-unit credit is not awarded.
The course is finished with a colloquium - discussion with the teacher, who decides, whether the student's knowledge is sufficient. See the topics for the colloquium in the Study materials of the course.
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
Information on completion of the course: Základní podmínkou je absolvování všech seminářů, absence musí být omluveny cestou studijního oddělení do 5 dnů od začátku absence. Bude ukončen kolokviem – rozhovorem s vyučujícím, který ověří znalosti studentů.
The course is taught annually.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/1411/podzim2024/BHBB011s/index.qwarp
You can find all the important information about the course organisation, study materials, etc., in the Interactive syllabus of the course: https://is.muni.cz/auth/el/med/podzim2024/BHBB011s/index.qwarp.

The main source of knowledge for the exam are the seminars and seminar presentations. To supplement or extend your knowledge, you shall study the recommended literature on the topic. You can also arrange a consultation with one of the lecturers.

The course is also listed under the following terms Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023.
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