VSBC0422p Biochemistry II -l

Faculty of Medicine
Spring 2002
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: RZk (examination).
Teacher(s)
prof. MUDr. Vladimír Palyza, CSc. (lecturer)
doc. MUDr. Jaromír Sláma, CSc. (lecturer)
prof. RNDr. Eva Táborská, CSc. (lecturer)
Guaranteed by
doc. MUDr. Jaromír Sláma, CSc.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Syllabus
  • Digestion and absorption of lipids, plasma lipoproteins. Metabolism of fatty acids, ketogenesis. Synthesis of TG, fat mobilization.
  • Synthesis and breakdown of phospho- and glycolipids. Cholesterol biosynthesis and utilization.
  • Interrelationships among the major pathways involved in energy metabolism. The tricarboxylic acid cycle. Synthesis of haem.
  • Biosynthesis and catabolism of purine and pyrimidine nucleotides. Biological membranes and transport through membranes.
  • Mitochondria. Mitochondrial electron transport chain, proton motive force, synthesis of ATP, oxidative phosphorylation.
  • Chromatin, DNA replication and transcription. Protein synthesis by translation of mRNA and post-translational processing.
  • Proteins of striated muscle, muscle contraction. Similarities and differences between skeletal, cardiac, and smooth muscle.
  • Collagen synthesis and ripening, elastin, and proteoglycans.
  • Neurons, neurotransmission - cholinergic, adrenergic, and inhibitory synapses. The gastrointestinal tract.
  • Transport of oxygen and carbon dioxide. Control of acid-base balance. Blood osmolality, fluid and electrolyte balance.
  • Normal renal and hepatic functions.
  • Catabolism of haemoglobin, bilirubin metabolism, metabolism of iron, copper, and of xenobiotics.
  • Control of metabolism. Mechanism of hormone action, intracellular (soluble) and plasma membrane receptors.
  • The biological effects of some hormones. The immune response, antigens and immunoglobulin structures.
  • Chemical factors in the environment. Toxic and harmful compounds assigned to the risk and safety phrases under European legislation.
Literature
  • MURRAY, Robert, Daryl GRANNER, Peter MAYES and Victor RODWELL. Harperova biochemie (Harper's Biochemistry). 2. české vydání. Jinočany: Nakladatelství H & H, 1998, 872 pp. ISBN 80-85787-38-5. info
  • Biochemistry :a concise text for medical students. Edited by D. K. Apps. 5th ed. London: Bailliere Tindall, 1992, vii, 448 s. ISBN 0-7020-1444-3. info
Language of instruction
Czech
Further Comments
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2000, Spring 2001.
  • Enrolment Statistics (recent)
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