VSLC021p Medical chemistry -l

Faculty of Medicine
Spring 2001
Extent and Intensity
2/0/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. RNDr. Jiří Dostál, CSc. (lecturer)
prof. MUDr. Vladimír Palyza, CSc. (lecturer)
prof. RNDr. Eva Táborská, CSc. (lecturer)
Guaranteed by
doc. MUDr. Jaromír Sláma, CSc.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Syllabus
  • Information concerning medical chemistry. The basic chemical terms: substances, particles, amount of substance, some properties of a single particle and molar quantities. Electron configurations in atoms. Types of bonds, electronegativity. Non-covalent bonds and attraction forces.
  • Chemical reactions, kinetics, chemical equilibrium. The driving force of chemical reactions, free Gibbs energy.
  • Solutions of substances. Dissociation of electrolytes, the equilibria in electrolyte solutions.
  • Protolytic reactions: acids and bases, pH values, hydrolysis of salts, buffers.
  • Oxidation-reduction reactions, redox potentials, the e.m. force of a voltaic cell and the relation to the reaction free energy change.
  • Essential macroelements important for living matter, general properties of them and of some of their compounds.
  • Carbon compounds: their constitution, configuration, isomerism, and conformation. Types of organic compounds, the principals of nomenclature. Hydrocarbons, major types, structures, reactivity.
  • Derivatives of hydrocarbons: alcohols, thioalcohols, phenols, carbonyl compounds, and carboxylic acids.
  • Substituted carboxylic acids and derivatives of the acids (esters, amides, anhydrides, halides).
  • Amines and the other derivatives of hydrocarbons.
  • Heterocyclic compounds and biochemically important derivatives. Alkaloids.
  • Structures and properties of monosaccharides. Simple sugar derivatives. Oligosaccharides, polysaccharides.
  • Heteroglycosides. Nucleosides, nucleotides, structures of nucleic acids.
  • Fatty acids and alcohols in lipids. Triacylglycerols and waxes. Phospholipids and glycolipids.
  • Icosanoids. Isoprenoids. Steroids, structures of representative compounds.
  • Standard and other alpha-amino acids, structures and common properties, polarity. Peptides, some groups of peptides exhibiting biological activity.
  • Proteins, main features of the structure of globular, fibrous, and membrane proteins. Glycoproteins. Haemoproteins, haem and other tetrapyrrols.
Literature
  • Základy biologickej chémie a enzymológie. Edited by Ľudovít Bergendi - Jozef Čársky - Ivan Pecháň. [1. vyd.]. Bratislava: PALAESTRA, 1997, 385 s. ISBN 80-88718-05-8. info
  • HOLUM, John R. Elements of General and Biological Chemistry. 8. ed. New York: John Wiley & Sons, 1991, 425 s., 53. ISBN 0-471-51757-7. info
  • Organic chemistry :a short course. Edited by Harold Hart. 9th ed. Boston: Houghton Mifflin Company., xx, 572 s. ISBN 0-395-70838-9. info
Language of instruction
Czech
Further Comments
The course is taught annually.
The course is taught: every week.
The course is also listed under the following terms Spring 2000.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/med/spring2001/VSLC021p