BLKH0311p Clinical Haematology - lecture

Faculty of Medicine
Autumn 2008
Extent and Intensity
2/0/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. MUDr. Miroslav Penka, CSc. (lecturer)
Michaela Gregorovičová (assistant)
Guaranteed by
prof. MUDr. Miroslav Penka, CSc.
Department of Laboratory Methods – Departments of Non-medical Branches – Faculty of Medicine
Contact Person: MUDr. Alena Buliková, Ph.D.
Timetable
Thu 14:00–16:30 B09/324
Prerequisites (in Czech)
BLMB011p Biology - lecture
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
This course includes information about the origin, development, structure and function of the system of hematopoietic cells and organs as well as of the blood clotting system. Both of them are described not only in health but also during various diseases inherited and acquired. Students will receive information summarizing pathophysiologic mechanisms, clinical and mainly laboratory findings in hematologic diseases and laboratory assays serving for treatment’s maintenance. The knowledge will allow students to interpret results obtained during hematological laboratory examination for diagnosis establishing and/or for differential diagnoses.
Syllabus
  • Origin and development of blood cells.
  • Basic principles of blood coagulation.
  • Plasmatic clotting factors, their physiology. Inherited bleeding disorders.
  • Primary hemostasis, platelet plug formation and its abnormalities.
  • Basic principles of anti-platelet therapy.
  • Inherited thrombophilias, anti-thrombotic treatment and its monitoring.
  • Acquired disorders of blood clotting.
  • Red cell disorders.
  • Myeloproliferative neoplasms.
  • Acute leukaemias.
  • Myelodyspastic syndrome.
  • Lymphoproliferative disorders.
  • Flow cytometry and molecular genetic assays for diagnosis of hematology diseases.
  • Therapeutic aphaeresis, basic principles of hemopoietic cells transplantation.
Literature
  • PECKA, Miroslav. Laboratorní hematologie v přehledu : fyziologie a patofyziologie krevní buňky. 1. vyd. Český Těšín: FINIDR, 2006, 304 s. ISBN 8086682021. info
  • PECKA, Miroslav. Laboratorní hematologie v přehledu : fyziologie a patofyziologie hemostázy. 1. vyd. Český Těšín: FINIDR, 2004, 237 s. ISBN 808668203X. info
  • PECKA, Miroslav. Přehled laboratorní hematologie. Bílá krevní řada, krevní destičky. [1. vyd.]. Praha: Galén, 1996, 132 s. ISBN 8085824434. info
  • Přehled laboratorní hematologie 1 :Krvetvorba. Červená krevní řada. Edited by Miroslav Pecka. [1. vyd.]. Praha: Galén, 1995, 141 s. ISBN 80-85824-28-0. info
Assessment methods
Lectures. The course is closed by practical and oral examination.
Language of instruction
Czech
Further Comments
Study Materials
The course is also listed under the following terms Autumn 2006, Autumn 2007, Spring 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (Autumn 2008, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2008/BLKH0311p