BLLK051p Liquorology - lecture

Faculty of Medicine
Autumn 2008
Extent and Intensity
2/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. MUDr. Milan Dastych, CSc., MBA (lecturer)
Michaela Gregorovičová (assistant)
Guaranteed by
doc. MUDr. Milan Dastych, CSc., MBA
Department of Laboratory Methods – Departments of Non-medical Branches – Faculty of Medicine
Contact Person: Michaela Gregorovičová
Timetable
Mon 15:00–16:40 N05001
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The goal of theoretical part considering the subject of laboratory diagnosis of neurological diseases is to become familier with the modern conception of cerebrospinal fluid analysis. Sensitive immunochemical methods improve to make diagnosis of inflammatory and degenerative damages of nervous system. It is neccesssary to provide information related to indications and above all interpretations of results of the particular methods considering clinical units. In the practical part students gain experience with executing particular methods in cerebrospinal fluid analysis at least within the range that the graduate is able to join the working team of laboratory dealing with diagnosis of neurological diseases.
Syllabus
  • Preanalytical stage ; Total protein; Glukose, lactate ; Albumin, Q albumin (blood-CSF barrier); Disturbances of the blood-CSF barier; Detection of intrathecal immunoglobulin synthesis ; CSF/serum ratio diagram (Oligoclonal bands, isoelectric focusing); Paraneoplastic antibodies (anti-Hu, anti-Ri, anti- Yo); CSF cells – quantitative, qualitative; Acute meningitis, tuberculous meningitis, neuroborreliosis, brain tumors, brain infarction, polyneuropathies, HIV encephalitis, chronic inflammatory processes, multiple sclerosis; Markers of tissue destruction;
Literature
  • DASTYCH, Milan, Zdeňka ČERMÁKOVÁ, Pavel ŠTOURAČ, Alena ŠEVČÍKOVÁ, Iva KOCMANOVÁ and Svatava SNOPKOVÁ. Mikroskopický nález kryptokoka v mozkomíšním moku jako první příznak rozvinutého stadia AIDS: kazuistika. (Microskopis detection of Cryptococcus in the cerebrospinal fluid as the first symptom of the advanced stage of AIDS - a case study.). Česká a slovenská neurologie a neurochirurgie. Brno: Medica Healthworld, 2008, 71/104, No 1, p. 93-96. ISSN 1802-4041. info
Assessment methods
examination
Language of instruction
Czech
The course is also listed under the following terms Autumn 2007, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (Autumn 2008, recent)
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