BVZF0321p Basics of Pharmacology I - lecture

Faculty of Medicine
Autumn 2008
Extent and Intensity
1/0/0. 1 credit(s). Type of Completion: z (credit).
Teacher(s)
prof. MUDr. Alexandra Šulcová, CSc. (lecturer)
prof. MUDr. Eva McCaskey Hadašová, CSc. (lecturer)
MUDr. Jana Nováková, Ph.D. (lecturer)
MUDr. Jana Pistovčáková, Ph.D. (lecturer)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (lecturer)
doc. PharmDr. Jan Juřica, Ph.D. (lecturer)
doc. PharmDr. Ondřej Zendulka, Ph.D. (lecturer)
MVDr. Dagmar Vršková, Ph.D. (lecturer)
MUDr. Mgr. Karel Šlais, Ph.D. (lecturer)
Guaranteed by
prof. MUDr. Alexandra Šulcová, CSc.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: Renata Bláblová
Timetable
each even Thursday 13:00–14:40 P31 Posluchárna A. I. Bláhy
Prerequisites (in Czech)
VSBC0221p Biochemistry I -lect.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Students are expected to obtain: a) from lectures and seminars: a clarification of integration in the field of biomedical subjects such as chemistry, physiology, molecular biology, pathology and pathological physiology enabling them to understand why, what mechanism by, and what conditions on, drugs and their combinations may elicit therapeutic, adverse, and toxic effects. They will acquire an orientation in drug classes according to their main therapeutic indications with a special attention paid to common drug-drug interactions. Information on drug development process, rules of preclinical and clinical drug testing will also be given; b) from practicals a training in practical skills in "pharmacological thinking" in cases of need to make a choice of drug, dosing regimen, route and techniques of administration, and an elimination of adverse interactions with drugs simultaneously given.
Syllabus
  • AUTUMN SEMESTER
  • 1.LECTURE: Drug classification. Mechanisms of drug effects. Basic pharmacokinetics. Drug interactions.
  • 2.LECTURE: Adverse drug effects. General management of poisoning. Drug dependence. Rational Pharmacotherapy.
  • 3.SEMINAR: Drug prescription. Survey of drug dosage forms. Pharmacopoea.
  • 4.SEMINAR: Pharmacology of autonomic nervous system. Receptors and their pharmacological influence.
  • 5.SEMINAR: Pharmacology of allergy. Histamine and antihistamine drugs. Drugs used in asthma.
  • 6.LECTURE: Neurotropic drugs. Anaesthetics, analgesics, psychotropic drugs.
  • 7.LECTURE: Antibiotics and chemotherapeutic drugs.
  • 8.SEMINAR: Revision, credits. multiplechoice test
  • SPRING SEMESTER
  • SEMINARS:
  • 1. Practical preparation of selected drug dosage forms.
  • 2. Pharmacokinetic processes and parameters. Therapeutic drug monitoring.
  • 3. The use of computer techniques in pharmacokinetics. Practical computations of basic pharmacokinetic parameters.
  • 4. Pathophysiology and therapy of peptic ulcers. Antiemetics.
  • 5. Pathophysiology and therapy of diabetes mellitus. Insulines. Peroral antidiabetic drugs.
  • 6. Glucokorticoids, mechanism of effect. Anabolic drugs.
  • 7. Pharmacotherapy of neoplastic diseases. Imunomodulation, imunosupression. Multiplechoice test.
  • 8. Vitamins B, C, A, D, E, K. Supplements.
  • LECTURES:
  • 1. Toxicants in nutritional chains - antibiotics, pesticides, etc.
  • 2. Nutritional pharmacology. Natural fiber, aminoacids, fish oils, fatty acids. Toxicants and additives in food. Tanins, glutamate, food preservatives and dyes. Dietary factors affecting drug efficacy. Drug effects on nutrient status..
  • 3. Drugs of abuse. Influence of smoking, therapy and prevention.
  • 4. Basic of phytopharmacology. What is homeopathy
  • 5. Medical plants and their use.
  • 6. Excursion to the Center of medical plants. Credits.
Literature
  • MARTÍNKOVÁ, Jiřina. Farmakologie pro studenty zdravotnických oborů. 1. vyd. Praha: Grada, 2007, 379 s. ISBN 9788024713564. info
  • MACH, Ivan. Doplňky stravy na našem trhu. Vyd. 1. Praha: Svoboda Servis, 2006, 118 s. ISBN 8086320464. info
  • PERLÍK, František. Základy farmakologie : klinická a speciální farmakologie. 1. vyd. Praha: Karolinum, 2005, 190 s. ISBN 8024611392. URL info
  • LÜLLMANN, Heinz. Barevný atlas farmakologie. 2., přeprac. a dopl. vyd. Praha: Grada, 2001, 382 s. ISBN 807169973X. info
  • HYNIE, Sixtus. Farmakologie v kostce. 2., přeprac. vyd. V Praze: Triton, 2001, 520 s. ISBN 8072541811. info
  • HYNIE, Sixtus. Farmakologie pro bakalářské studium. 2. přeprac. vyd. Praha: Karolinum, 1996, 272 s. ISBN 8071841846. info
  • HYNIE, Sixtus. Farmakologie pro bakalářské studium. 2. přeprac. vyd. Praha: Karolinum, 1996, s. i-x. ISBN 8071841854. info
  • Vybrané kapitoly z učebnice: http://books.google.cz/books?id=7lNQpLuETq4C&printsec=frontcover&dq=farmakologie&lr=&as_brr=3#PPA4,M1
  • Vybrané kapitoly z učebnice: http://books.google.cz/books?ct=result&q=farmakologie&lr=&as_brr=3&sa=N&start=0
Assessment methods
During the studying the students have to prove active knowledge of pharmacology acquired. The students have to pass the final written multiple-choice test.
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
The course is also listed under the following terms Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (Autumn 2008, recent)
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