LF:VSFY0321s Physiology I - seminar - Course Information

VSFY0321s Physiology I - seminar

Extent and Intensity

0/1/0. 4 credit(s). Type of Completion: z (credit).

Teacher(s)

MUDr. Mohamed Al-Kubati, CSc. (seminar tutor)
doc. MUDr. Alena Damborská, Ph.D. (seminar tutor)
MUDr. Petr Lokaj, Ph.D. (seminar tutor)
prof. MUDr. Marie Nováková, Ph.D. (seminar tutor)
MUDr. Zuzana Nováková, Ph.D. (seminar tutor)
doc. MUDr. Robert Roman, Ph.D. (seminar tutor)
doc. MUDr. Zdeněk Wilhelm, CSc. (seminar tutor)
MUDr. Bc. Eva Závodná, Ph.D. (seminar tutor)
Mirka Hanousková (assistant)

Guaranteed by

prof. MUDr. Nataša Honzíková, CSc.
Department of Physiology – Theoretical Departments – Faculty of Medicine

Timetable of Seminar Groups

VSFY0321s/01: Mon 15. 9. to Fri 19. 9. Tue 13:00–15:30 249, Mon 6. 10. to Fri 10. 10. Tue 13:00–15:30 249, Mon 27. 10. to Fri 31. 10. Tue 13:00–15:30 249, Mon 17. 11. to Fri 21. 11. Tue 13:00–15:30 249
VSFY0321s/02: Mon 15. 9. to Fri 19. 9. Tue 13:00–15:30 249, Mon 6. 10. to Fri 10. 10. Tue 13:00–15:30 249, Mon 27. 10. to Fri 31. 10. Tue 13:00–15:30 249, Mon 17. 11. to Fri 21. 11. Tue 13:00–15:30 249
VSFY0321s/03: Mon 15. 9. to Fri 19. 9. Tue 13:00–15:30 249, Mon 6. 10. to Fri 10. 10. Tue 13:00–15:30 249, Mon 27. 10. to Fri 31. 10. Tue 13:00–15:30 249, Mon 17. 11. to Fri 21. 11. Tue 13:00–15:30 249
VSFY0321s/04: Mon 15. 9. to Fri 19. 9. Tue 13:00–15:30 249, Mon 6. 10. to Fri 10. 10. Tue 13:00–15:30 249, Mon 27. 10. to Fri 31. 10. Tue 13:00–15:30 249, Mon 17. 11. to Fri 21. 11. Tue 13:00–15:30 249
VSFY0321s/05: Mon 22. 9. to Fri 26. 9. Tue 13:00–15:30 249, Mon 13. 10. to Fri 17. 10. Tue 13:00–15:30 249, Mon 3. 11. to Fri 7. 11. Tue 13:00–15:30 249, Mon 24. 11. to Fri 28. 11. Tue 13:00–15:30 249
VSFY0321s/06: Mon 22. 9. to Fri 26. 9. Tue 13:00–15:30 249, Mon 13. 10. to Fri 17. 10. Tue 13:00–15:30 249, Mon 3. 11. to Fri 7. 11. Tue 13:00–15:30 249, Mon 24. 11. to Fri 28. 11. Tue 13:00–15:30 249
VSFY0321s/07: Mon 15. 9. to Fri 19. 9. Tue 15:45–18:15 249, Mon 6. 10. to Fri 10. 10. Tue 15:45–18:15 249, Mon 27. 10. to Fri 31. 10. Tue 15:45–18:15 249, Mon 17. 11. to Fri 21. 11. Tue 15:45–18:15 249
VSFY0321s/08: Mon 15. 9. to Fri 19. 9. Tue 15:45–18:15 249, Mon 6. 10. to Fri 10. 10. Tue 15:45–18:15 249, Mon 27. 10. to Fri 31. 10. Tue 15:45–18:15 249, Mon 17. 11. to Fri 21. 11. Tue 15:45–18:15 249
VSFY0321s/09: Mon 22. 9. to Fri 26. 9. Tue 13:00–15:30 249, Mon 13. 10. to Fri 17. 10. Tue 13:00–15:30 249, Mon 3. 11. to Fri 7. 11. Tue 13:00–15:30 249, Mon 24. 11. to Fri 28. 11. Tue 13:00–15:30 249
VSFY0321s/10: Mon 22. 9. to Fri 26. 9. Tue 13:00–15:30 249, Mon 13. 10. to Fri 17. 10. Tue 13:00–15:30 249, Mon 3. 11. to Fri 7. 11. Tue 13:00–15:30 249, Mon 24. 11. to Fri 28. 11. Tue 13:00–15:30 249
VSFY0321s/11: Mon 15. 9. to Fri 19. 9. Tue 15:45–18:15 249, Mon 6. 10. to Fri 10. 10. Tue 15:45–18:15 249, Mon 27. 10. to Fri 31. 10. Tue 15:45–18:15 249, Mon 17. 11. to Fri 21. 11. Tue 15:45–18:15 249
VSFY0321s/12: Mon 15. 9. to Fri 19. 9. Tue 15:45–18:15 249, Mon 6. 10. to Fri 10. 10. Tue 15:45–18:15 249, Mon 27. 10. to Fri 31. 10. Tue 15:45–18:15 249, Mon 17. 11. to Fri 21. 11. Tue 15:45–18:15 249
VSFY0321s/13: Mon 29. 9. to Fri 3. 10. Tue 13:00–15:30 249, Mon 20. 10. to Fri 24. 10. Tue 13:00–15:30 249, Mon 10. 11. to Fri 14. 11. Tue 13:00–15:30 249, Mon 1. 12. to Fri 5. 12. Tue 13:00–15:30 249
VSFY0321s/14: Mon 29. 9. to Fri 3. 10. Tue 13:00–15:30 249, Mon 20. 10. to Fri 24. 10. Tue 13:00–15:30 249, Mon 10. 11. to Fri 14. 11. Tue 13:00–15:30 249, Mon 1. 12. to Fri 5. 12. Tue 13:00–15:30 249
VSFY0321s/15: Mon 29. 9. to Fri 3. 10. Tue 13:00–15:30 249, Mon 20. 10. to Fri 24. 10. Tue 13:00–15:30 249, Mon 10. 11. to Fri 14. 11. Tue 13:00–15:30 249, Mon 1. 12. to Fri 5. 12. Tue 13:00–15:30 249
VSFY0321s/16: Mon 29. 9. to Fri 3. 10. Tue 13:00–15:30 249, Mon 20. 10. to Fri 24. 10. Tue 13:00–15:30 249, Mon 10. 11. to Fri 14. 11. Tue 13:00–15:30 249, Mon 1. 12. to Fri 5. 12. Tue 13:00–15:30 249
VSFY0321s/17: Mon 22. 9. to Fri 26. 9. Tue 15:45–18:15 249, Mon 13. 10. to Fri 17. 10. Tue 15:45–18:15 249, Mon 3. 11. to Fri 7. 11. Tue 15:45–18:15 249, Mon 24. 11. to Fri 28. 11. Tue 15:45–18:15 249
VSFY0321s/18: Mon 22. 9. to Fri 26. 9. Tue 15:45–18:15 249, Mon 13. 10. to Fri 17. 10. Tue 15:45–18:15 249, Mon 3. 11. to Fri 7. 11. Tue 15:45–18:15 249, Mon 24. 11. to Fri 28. 11. Tue 15:45–18:15 249
VSFY0321s/19: Mon 29. 9. to Fri 3. 10. Tue 15:45–18:15 249, Mon 20. 10. to Fri 24. 10. Tue 15:45–18:15 249, Mon 10. 11. to Fri 14. 11. Tue 15:45–18:15 249, Mon 1. 12. to Fri 5. 12. Tue 15:45–18:15 249
VSFY0321s/20: Mon 29. 9. to Fri 3. 10. Tue 15:45–18:15 249, Mon 20. 10. to Fri 24. 10. Tue 15:45–18:15 249, Mon 10. 11. to Fri 14. 11. Tue 15:45–18:15 249, Mon 1. 12. to Fri 5. 12. Tue 15:45–18:15 249
VSFY0321s/26: No timetable has been entered into IS.
VSFY0321s/27: No timetable has been entered into IS.
VSFY0321s/28: No timetable has been entered into IS.
VSFY0321s/29: No timetable has been entered into IS.
VSFY0321s/30: No timetable has been entered into IS.

Prerequisites (in Czech)

VSLC011p Med.Chem.- lecture && VSBI0222p Biology II - lecture && ( STBF011p Biophysics || VLBF011p Biophysics-lect. ) && VSBC0221s Biochemistry I-sem.

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• General Medicine (eng.) (programme LF, M-VL)
• General Medicine (programme LF, M-VL)

Course objectives

The goal of physiology is to explain the physical and chemical factors that are responsible for the origin, development, and progression of the life. In human physiology, we attempt to explain the specific characteristics and mechanisms of the human body that make it a living being. In the course of lectures, student gets hold of knowledge of general and systematic human physiology, learns how to analyse special text and how to find relevant and substantive information, to cover basic relationships and regulations in living systems, including basic knowledge of biocybernetics. After finishing normal physiology course, the student is acquainted with main basic experimental methods used in physiology, mainly by a form of practices. During practices, the student must get acquainted with current examination methods, used in everyday clinical physiology (e.g. electrocardiography, electroencephalography, electromyography, spirometry), including exercise tests (ergometry). Students must make conclusions from their own measured values. The main outcome of normal physiology studies is therefore to teach the students not only the review of physiology, but also to enable them to get practical skills and support critical scientific way of thinking.

Syllabus

• Program of TUTORIAL I: Intercellular contact Mechanical, electrical and humoral coupling, ligands and receptors. Second messengers. Resting membrane potential Na/K ATP-ase, diffusion currents, electro-chemical gradient, equilibrium potential. Physiological importance of resting membrane potential. Action potential Local responses, selective conductivity of membrane channels, mechanism of depolarization, transpolarization and repolarization. Principles of muscle contraction Contractile proteins, troponin and tropomyosin, role of calcium, mechanism of relaxation. Differences between smooth, skeletal and heart muscle. Program of TUTORIAL II: Interpretation of the ECG curve a) Electric field of the heart as a vector ( source, determinants, projection on the body surface ) b) Limb and chest leads ( bipolar, unipolar ) c) Construction of the mean electrical axis of the heart ( Eindhoven triangle, paralelogram ) d) Diagnostic value of ECG Cardiac cycle a) Phases of cardiac cycle and their time course ( polygram, intracardiac pressures, heart volume, heart sounds ) b) Phases of cardiac cycle in pressure / volume representation ( effect of changes in preload and afterload ) Autoregulation of cardiac functions a) Starling principle b) Effect of frequency on contractility c) Effect of frequency on the duration of action potential ( Q-T interval ) Program of TUTORIAL III: Heart as a muscle a) Cardiac contractility and its measurement b) Stroke scheme, cardiac output, ejection fraction c) Cardiac energetics Coronary circulation a) Anatomy and functional features ( specialties ) b) Regulation of coronary flow c) Coronary reserve and ischaemic heart disease Rheology ( of blood circulation ) a) Resistance and capacitance vessels b) Poisseuiles law, Laplaces law c) Blood pressure in separate ( different ) parts of blood circulation Program of TUTORIAL IV: Immune mechanisms 1) Development of the immune system. T lymphocytes, B lymphocytes, memory T and B cells, antigen presenting cells. Clones. 2) Cellular immunity. Major histocompatibility complex. NK cells, T4 helper cells, T8 killer cells, T8 suppressor cells. 3) Humoral immunity. Immunoglobulins IgG, IgA, IgM, IgE. 4) The complement system. C1 - C9. Properdin. 5) Lymphokines and cytokines. IL 1, IL 2, IL 3. Colony stimulating factors, GM - CSF. Interferons. Tumor necrosis factor.

Literature

• GANONG, William F. Přehled lékařské fyziologie. 20. vyd. Praha: Galén, 2005, xx, 890. ISBN 8072623117. info
• GANONG, William F. Review of medical physiology. 22nd ed. New York: Lange Medical Books/McGraw-Hill, 2005, xii, 912. ISBN 0071440402. info
• SILBERNAGL, Stefan and Agamemnon DESPOPOULOS. Atlas fyziologie člověka. 6. vyd., zcela přeprac. a r. Praha: Grada, 2004, xiii, 435. ISBN 802470630X. info
• GUYTON, Arthur C. and John E. HALL. Textbook of medical physiology. 11th ed. Philadelphia: Elsevier Saunders, 2006, xxxv, 1116. ISBN 0721602401. info
• DESPOPOULOS, Agamemnon and Stefan SILBERNAGL. Color atlas of physiology. Translated by Suzyon O'Neal Wandrey. 5th ed., completely rev. and. Stuttgart: Thieme, 2003, xiii, 436. ISBN 1588900614. info

Assessment methods

Class discussion on the base of materials in the textbook. Giving the course-unit credit is conditioned by full attendance in the lessons.

Language of instruction

Czech

Further comments (probably available only in Czech)

Information on completion of the course: Absolvování seminářů je podmínkou k udělění zápočtu.
The course is taught annually.

Teacher's information

http://www.med.muni.cz/fyziol

• Enrolment Statistics (Autumn 2008, recent)
  
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