BVZF052 Basis of Pharmacology

Faculty of Medicine
Autumn 2009
Extent and Intensity
1/2. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. MUDr. Alexandra Šulcová, CSc. (lecturer)
prof. MUDr. Eva McCaskey Hadašová, CSc. (lecturer)
MUDr. Jana Pistovčáková, Ph.D. (lecturer)
MVDr. Dagmar Vršková, Ph.D. (lecturer)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (lecturer)
MUDr. Mgr. Karel Šlais, Ph.D. (seminar tutor)
doc. PharmDr. Jan Juřica, Ph.D. (seminar tutor)
doc. PharmDr. Jana Rudá, Ph.D. (seminar tutor)
doc. PharmDr. Ondřej Zendulka, Ph.D. (seminar tutor)
Mgr. Barbora Říhová, Ph.D. (seminar tutor)
PharmDr. Lucia Zendulková Zahradníková, Ph.D. (seminar tutor)
MUDr. Jana Nováková, Ph.D. (seminar tutor)
PharmDr. Hana Kolaříková (lecturer)
MUDr. Jana Nováková, Ph.D. (lecturer)
PharmDr. Hana Kolaříková (seminar tutor)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (seminar tutor)
MUDr. Jana Pistovčáková, Ph.D. (seminar tutor)
MVDr. Dagmar Vršková, Ph.D. (seminar tutor)
Guaranteed by
prof. MUDr. Alexandra Šulcová, CSc.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: prof. MUDr. Alexandra Šulcová, CSc.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
From the course on pharmacology students are expected to obtain: a) from lectures and seminars: a clarification of integration in the field of biomedical subjects such as chemistry, physiology, molecular biology, pathology and pathological physiology enabling them to understand why, what mechanism by, and what conditions on, drugs and their combinations may elicit therapeutic, adverse, and toxic effects. They will acquire an orientation in drug classes according to their main therapeutic indications with an attention paid to common drug-drug interactions. Information on drug development process, rules of preclinical and clinical drug testing will also be given. b) from practicals: a training in practical skills in "pharmacological thinking" in cases of need to make a choice of drug, dosing regimen, route and techniques of administration, and an elimination of adverse interactions with drugs simultaneously given.
Syllabus
  • AUTUMN SEMESTER
  • 1.LECTURE: Drug classification. Mechanisms of drug effects. Basic pharmacokinetics. Drug interactions.
  • 2.LECTURE: Adverse drug effects. General management of poisoning. Drug dependence. Rational Pharmacotherapy.
  • 3.SEMINAR: Drug prescription. Survey of drug dosage forms. Pharmacopoea.
  • 4.SEMINAR: Pharmacology of autonomic nervous system. Receptors and their pharmacological influence.
  • 5.SEMINAR: Pharmacology of allergy. Histamine and antihistamine drugs. Drugs used in asthma.
  • 6.LECTURE: Neurotropic drugs. Anaesthetics, analgesics, psychotropic drugs.
  • 7.LECTURE: Antibiotics and chemotherapeutic drugs.
  • 8.SEMINAR: Revision, credits. multiplechoice test
  • SPRING SEMESTER
  • SEMINARS:
  • 1. Practical preparation of selected drug dosage forms.
  • 2. Pharmacokinetic processes and parameters. Therapeutic drug monitoring.
  • 3. The use of computer techiques in pharmacokinetics. Practical computations of basic pharmacokinetic parameters.
  • 4. Pathophysiology and therapy of peptic ulcers. Antiemetics.
  • 5. Pathophysiology and therapy of diabetes mellitus. Insulines. Peroral antidiabetic drugs.
  • 6. Glucokorticoids, mechanism of effect. Anabolic drugs.
  • 7. Pharmacotherapy of neoplastic diseases. Imunomodulation, imunosupression. Multiplechoice test.
  • 8. Vitamins B, C, A, D, E, K. Supplements.
  • LECTURES:
  • 1. Toxicants in nutritional chains - antibiotics, pesticides, etc.
  • 2. Nutritional pharmacology. Natural fiber, aminoacids, fish oils, fatty acids. Toxicants and additives in food. Tanins, glutamate, food preservatives and dyes. Dietary factors affecting drug efficacy. Drug effects on nutrient status..
  • 3. Drugs of abuse. Influence of smoking, therapy and prevention.
  • 4. Basic of phytopharmacology. What is homeopathy
  • 5. Medical plants and their use.
  • 6. Excursion to the Center of medical plants. Credits.
Literature
  • MARTÍNKOVÁ, Jiřina. Farmakologie pro studenty zdravotnických oborů. 1. vyd. Praha: Grada, 2007, 379 s. ISBN 9788024713564. info
  • MACH, Ivan. Doplňky stravy na našem trhu. Vyd. 1. Praha: Svoboda Servis, 2006, 118 s. ISBN 8086320464. info
  • PERLÍK, František. Základy farmakologie : klinická a speciální farmakologie. 1. vyd. Praha: Karolinum, 2005, 190 s. ISBN 8024611392. URL info
  • LÜLLMANN, Heinz, Klaus MOHR and Lutz HEIN. Barevný atlas farmakologie. Translated by Maxmilián Wenke - Elfrída Mühlbachová. 3. vyd. Praha: Grada, 2007, xi, 372. ISBN 9788024716725. info
  • HYNIE, Sixtus. Farmakologie v kostce. 2., přeprac. vyd. V Praze: Triton, 2001, 520 s. ISBN 8072541811. info
  • HYNIE, Sixtus. Farmakologie pro bakalářské studium. 2. přeprac. vyd. Praha: Karolinum, 1996, 272 s. ISBN 8071841846. info
  • HYNIE, Sixtus. Farmakologie pro bakalářské studium. 2. přeprac. vyd. Praha: Karolinum, 1996, s. i-x. ISBN 8071841854. info
  • Vybrané kapitoly z učebnice: http://books.google.cz/books?ct=result&q=farmakologie&lr=&as_brr=3&sa=N&start=0
  • Vybrané kapitoly z učebnice: http://books.google.cz/books?id=7lNQpLuETq4C&printsec=frontcover&dq=farmakologie&lr=&as_brr=3#PPA4,M1
Assessment methods
During the studying the student has to prove active knowledge of pharmacology acquired. The student has to pass the written multiple-choice test to get the credit.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught every week.
The course is also listed under the following terms Autumn 2000, Autumn 2001, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2010.
  • Enrolment Statistics (Autumn 2009, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2009/BVZF052