ZLBI0121p Biology I - lecture

Faculty of Medicine
Autumn 2012
Extent and Intensity
1/2/0. 0 credit(s). Type of Completion: -.
Teacher(s)
prof. Ing. Petr Dvořák, CSc. (lecturer)
prof. MUDr. Marie Kopecká, CSc. (lecturer)
Albano Meli, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. Augustin Svoboda, CSc., dr. h.c. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
RNDr. Mário Špírek, PhD. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
doc. Yuh-Man Wadeley, Doctor of Philosophy (lecturer)
Mgr. Hana Hříbková, Ph.D. (seminar tutor)
Mgr. Kateřina Vopěnková, Ph.D. (seminar tutor)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
each odd Wednesday 7:30–9:20 B11/234
  • Timetable of Seminar Groups:
ZLBI0121p/ZLA: Thu 11:30–12:20 B11/334
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The course provides an overview of the current knowledge of molecular biology and cell biology in the context of other theoretical branches of the Faculty of Medicine. Recent and modern concepts of molecular cell structures, functional organization of the cell and gene expression and regulation are presented to students. As an extension of these topics, a molecular mechanism of gametogenesis and fertilization as well as cell division and cell cycle are discussed. In addition, a short introduction to genomics and analyses of the human genome is included. The subject matter presented in this course will help to better understand other subjects including physiology, pathology and human and clinical genetics.
Syllabus
  • Week 1: 17.-21.9.2012 Lecture: Introduction to medical biology - from understanding of cellular principle to modern biomedicine (Prof. Ing. Petr Dvořák, CSc.) Week 2: 24.-28.9.2012 Lecture: Basic architecture and function of eukaryotic cells (Prof. MUDr. Augustin Svoboda, CSc.) Week 3: 1.- 5.10.2012 Lecture: Architecture, molecular biology and pathology of eukaryotic cell nucleus (Doc. MUDr. Iva Slaninová, Ph.D) Week 4: 8.–12.10.2012 Lecture: Plasma membrane structure and function (Prof. MUDr. Augustin Svoboda, CSc.) Week 5: 15.-19.10.2012 Lecture: Molecular mechanisms of cell adhesions and intercellular communications (Prof. MUDr. Augustin Svoboda, CSc.) Week 6: 22.-26.10.2012 Lecture: Cytoskeleton and cell migration in health and disease (Prof. MUDr. Marie Kopecká, CSc.) Week 7: 29.10–2.11.2012 Lecture: From genotype to phenotype - introduction to molecular genetics (Doc. MUDr. David Šmajs, Ph.D.) Week 8: 5.-9.11.2012 Lecture: Regulation of gene expression - principles and examples (Doc. MUDr. David Šmajs, Ph.D.) Week 9: 12.-16.11.2012 Lecture: Molecular mechanisms regulating cell cycle and cell proliferation (Mgr. Stjepan Uldrijan, CSc.) Week 10: 19.-23.11.2012 Lecture: Mitosis and cytokinesis in normal and cancer cells (Prof. MUDr. Marie Kopecká, CSc.) Week 11: 26.-30.11.2012 Lecture: Cell differentiation and tissue engineering (Prof. Ing. Petr Dvořák, CSc.) Week 12: 3.-7.12.2012 Lecture: Cell death - mechanisms, implication for medical research (Doc. MUDr. Iva Slaninová, Ph.D.) Week 13: 10.-14.12.2012 Lecture: Biosynthesis of proteins in eukaryotic cells (RNDr. Mário Špírek, Ph.D.) Week 14: 17.-21.12.2012 Lecture: Principles of comparative and functional genomics (Doc. MUDr. David Šmajs, Ph.D.)
Literature
    recommended literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
  • ALBERTS, Bruce. Essential cell biology : an introduction to the molecular biology of the cell. New York: Garland Publishing, 1998, xxii, 630. ISBN 0-8153-2045-0. info
  • Essential cell biology. Edited by Bruce Alberts. 3rd ed. New York: Garland Science, 2009, 1 sv. ISBN 9780815341307. info
  • CAMPBELL, Neil A. Biologie. Edited by Jane B. Reece. Vyd. 1. Brno: Computer Press, 2006, xxxiv, 133. ISBN 8025111784. info
  • CAMPBELL, Neil A. Biology. Edited by Jane B. Reece. 7th ed. San Francisco: Pearson/Benjamin Cummings, 2005, xl, 1231. ISBN 080537146X. info
  • PRITCHARD Dorian J. a B. R. KORF: Základy lékařské genetiky, 1. české vydání, Galén 2007. ISBN 978-80-7262-449-2
  • SNUSTAD D. Peter a Michael D. SIMMONS: Principles of Genetics, 5th edition, Wiley&Sons 2009. ISBN-13: 978-0-470-38825-9
  • SNUSTAD, D. Peter, Michael J. SIMMONS, Jiřina RELICHOVÁ, Jiří DOŠKAŘ, Jiří FAJKUS, Petr HOŘÍN, Aleš KNOLL, Petr KUGLÍK, Jan ŠMARDA, Jana ŠMARDOVÁ, Renata VESELSKÁ and Boris VYSKOT. Genetika (Principles of Genetics). 1st ed. Brno: Masarykova univerzita, 2009, 894 pp. Učebnice. ISBN 978-80-210-4852-2. URL info
  • JANISCH, Roman. Overview of General Biology. 2. rozšířené. Brno: Masarykova univerzita, 2010, 91 pp. ISBN 978-80-210-5187-4. info
  • LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008, xxxvii, 11. ISBN 9780716776017. info
  • Pollard, Thomas D., Earnshaw, William C.: Cell Biology, 2nd edition, Saunders 2007. ISBN: 978-1-4160-2255-8
  • WOLPERT, L. Principles of development. 2nd ed. Oxford: Oxford University Press, 2002, xxv, 542. ISBN 0198792913. info
Teaching methods
lecture
Assessment methods
Lecture attendance is optional. Biology I (VSBI0121p) is required for Biology II (VSBI0222p) that ends up by written examination test. Students continue with Biology II (VSBI0222p) without proof of this semester's knowledge.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
Information on completion of the course: neukončuje se
The course is taught annually.
The course is also listed under the following terms Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (Autumn 2012, recent)
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