ZLPA0521c Pathology I - practice

Faculty of Medicine
Autumn 2012
Extent and Intensity
3/4/0. 3 credit(s). Type of Completion: z (credit).
Teacher(s)
doc. MUDr. Jiří Wotke, CSc. (seminar tutor)
prof. MUDr. Markéta Hermanová, Ph.D. (seminar tutor)
MUDr. Sylva Hotárková (seminar tutor)
MUDr. Iva Svobodová (seminar tutor)
MUDr. Víta Žampachová (seminar tutor)
Jarmila Jelínková (assistant)
MUDr. Karel Veselý, Ph.D. (seminar tutor)
Mgr. Iva Holušová (assistant)
doc. MUDr. Josef Feit, CSc. (seminar tutor)
MUDr. Jiří Lenz, Ph.D. (seminar tutor)
MUDr. Iva Staniczková Zambo, Ph.D. (seminar tutor)
Guaranteed by
prof. MUDr. Miroslav Hirt, CSc.
First Department of Pathology – Institutions shared with St. Anne's Faculty Hospital – Faculty of Medicine
Contact Person: doc. MUDr. Jiří Wotke, CSc.
Supplier department: First Department of Pathology – Institutions shared with St. Anne's Faculty Hospital – Faculty of Medicine
Timetable of Seminar Groups
ZLPA0521c/21: Mon 8. 10. to Fri 12. 10. each working day 7:30–10:00 PatÚI N01008, Mon 29. 10. to Fri 2. 11. each working day 7:30–10:00 PatÚI N01008
ZLPA0521c/22: Mon 24. 9. to Thu 27. 9. each working day 7:30–10:00 PatÚI N01008, Mon 15. 10. to Fri 19. 10. each working day 7:30–10:00 PatÚI N01008
ZLPA0521c/23: Mon 1. 10. to Fri 5. 10. each working day 7:30–10:00 PatÚI N01008, Mon 22. 10. to Fri 26. 10. each working day 7:30–10:00 PatÚI N01008
ZLPA0521c/40: No timetable has been entered into IS.
Prerequisites (in Czech)
ZLFY0422p Physiology II - lecture && ZLBC041p Biochemistry II -l && ZLAN0333p Anatomy III - lect. && ZLHE0322p Hist.and Embryol.II-lect. && ( ZLLT0222s Bas.Med.Terminology II-sem. || ZLLT0222p Bas. Med. Terminology -l ) && ZLET021p Ethics in Dent.-lect. && ZC041 Handling chemical substances
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main stress in the pathology course is given on macroscopic and microscopic correlation of diseases. After finishing the course the student should be able to: understand the basic pathologic processes (regressive changes, inflammaton, oncology, immune disorders); understand and be able to apply the basic classification of oncologic processes; understand the basic classification of etiologically defined processes (esp. infectious diseases); learn the most important methods used in diagnostic process and research (tissue processing, special stainings, histochemistry, immunohistochemistry, electron microscopy, molecular pathology); understand various disorders with respect to individual organs and organ systems; get familiar with the process of autopsy (the process of the autopsy and its evaluation); get familiar with laboratory processing of the tissue samples (description, tissue sampling);
Syllabus
  • General Pathology
  • Pathology and its role in medicine.
  • Methodology: autopsy, clinico-pathological correlation, surgical pathology (biopsy), ways of tissue examination and fixation
  • Cytology.
  • The disease, its definition and course. External and internal causes of a disease. Prevention.
  • Death (clinical and biological). Signs of death.
  • Regressive changes, necrosis (classification, causes). Atrophy: numeric and simple. Dystrophy: metabolic disorders of proteins, glycids, fat, water, minerals and pigments.
  • Inflammation: definition, local and general sings, microscopic and macroscopic. Inflammation: classification, nomenclature. Immunity disorders, transplantation pathology.
  • Progressive changes. Regeneration, reparation, wound healing. Hypertrophy, hyperplasia, metaplasia, dysplasia. Pseudotumors: cysts, pseudocysts, inflammatory pseudotumor. Disorders of embryonal development.
  • Tumors: definition, general properties, etiology, precanceroses. Biology of tumors: benign, malignant and uncertain tumors. Systematic classification of tumors: epithelial, mesenchymal, neuroectodermal and germinal tumors, choriocarcinoma, mesothelioma. Organ pathology
  • Disorders of the heart, circulation of the blood and lymph: Congenital and acquired heart diseases, changes in size and shape of the heart. Pathological contents of the pericardium. Inflammation, ischemic heart disease, myocardial infarction. Circulatory failure. Hypertension. Disorders of arteries and veins: atherosclerosis, aneurysm, inflammation, anemia, polycytemia. Local circulatory disorders: thrombosis, embolism. Bleeding. Lymfadenitis. Tumors.
  • Respiratory disorders: Pathology of upper respiratory pathways: rhinitis, laryngitis, bronchitis. Tumors and pseudotumors. Changes in pulmonary ventilation and circulation (venostasis, edema, induration, infarction, embolism). Silicosis and other external pigmentations. Superficial, interstitial and chronic inflammations of the lung. Pulmonary tumors. Pathology of the pleura.
  • Disorders of the gastrointestinal tract: Pathology of the oral cavity, pharynx, tonsillae and esophagus. Gastiris, peptic ulcers, gastric tumors. Pathology of the gut: disorders of circulation, inflammation. Appendicitis, malabsorption syndrome. Ileus, herniation. Intestinal tumors. Inflammation of the peritoneum, pathological contents of peritoneal cavity.
Literature
  • MAČÁK, Jirka. Obecná patologie. 1. vyd. Olomouc: Univerzita Palackého v Olomouci, 2002, 189 s. ISBN 8024404362. info
  • MAČÁK, Jirka and Jana MAČÁKOVÁ. Patologie (Pathology). první. Praha: GRADA, 2004, 347 pp. ISBN 80-247-0785-3. info
  • BUČEK, Jan. Praktikum z patologie :pitevní cvičení. 4. přepr. vyd. Brno: Masarykova univerzita, 1993, 88 s. ISBN 80-210-0721-4. info
  • FEIT, Josef, P. MIŘEJOVSKÝ and I. STEINER. Kontrolní otázky z patologie (Test question in pathology). 1st ed. Praha: Triton, 1998. ISBN 80-85875-89-6. info
Teaching methods
Pathology course consists of lectures and practical classes. Teaching consists of theoretical part (lectures) and practical part (laboratory practice). Practical courses consist of histological practice (microscopical and macroscopical images of autoptical and bioptical specimens are demonstrated and discussed) and autoptical practice (presence and ev. participation in autopsies). Hypertext teaching materials for the students are available in our teaching rooms as well in the Internet. These materials contain about 3000 images of various imaging methods (macroscopic, x-ray, CT, MRI images, histological images, partially available as virtual slides, videos). Lectures and practicals are complementary. General information and new updates on classifications as well as images are presented at the lectures. Practicals add further information, histopathologicaly and autoptical experience. Further information is provided in our web-based teaching materials. Various forms of testing is used to give the students proper feedback. Students are supposed to prepare for each practical lesson. The topic for each practical lesson as well as for each lecture is available.
Assessment methods
Lectures: 3 hours/week Practical classes: 4 hours/week; microscopic and autoptic lessons. The course of pathology is closed by oral exam. Attendance is compulsory; knowledge of the students is periodically tested during the practical classes. Testing can be either oral or written (multichoice tests, essay). Exam after two semesters of pathology has two parts: practical and theoretical. Practical part of the exam takes the form of a discussion over the microscop or over macroscopical or microscopical images. In theoretical part of the exam the students discuss after short preparation randomly selected topics. The list of these topics is available to the students in advance.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught each semester.
Listed among pre-requisites of other courses

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Teacher's information
http://www.muni.cz/atlases
The course is also listed under the following terms Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
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