VSBI0121p Biology I - lecture

Faculty of Medicine
Autumn 2013
Extent and Intensity
1/3/1. 0 credit(s). Type of Completion: -.
Teacher(s)
prof. Ing. Petr Dvořák, CSc. (lecturer)
prof. MUDr. Marie Kopecká, CSc. (lecturer)
doc. Mgr. Lumír Krejčí, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. Augustin Svoboda, CSc., dr. h.c. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
RNDr. Mário Špírek, PhD. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
doc. Yuh-Man Wadeley, Doctor of Philosophy (lecturer)
Mgr. Hana Hříbková, Ph.D. (seminar tutor)
Mgr. Kateřina Vopěnková, Ph.D. (seminar tutor)
Jana Růžičková (assistant)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Wed 10:30–11:20 B22/116 aula
  • Timetable of Seminar Groups:
VSBI0121p/VLA: Thu 11:30–12:20 B11/334
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; is able to deduce and explain the difference between healthy and pathologically-working cell; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
Syllabus
  • Week 1 (16.9.-20.9. 2013): Introduction to medical biology - from understanding of cellular principle to modern biomedicine (Prof. Ing. Petr Dvořák, CSc.)
  • Week 2 (23.9.-27.9.): Basic architecture and function of eukaryotic cells (Prof. MUDr. Augustin Svoboda, CSc.)
  • Week 3 (30.9.-4.10.): Plasma membrane structure and function (Prof. MUDr. Augustin Svoboda, CSc.)
  • Week 4 (7.10.-11.10.): Molecular mechanisms of cell adhesions and intercellular communications (Prof. MUDr. Augustin Svoboda, CSc.)
  • Week 5 (14.10.-18.10.): Cytoskeleton and cell migration in health and disease (Prof. MUDr. Marie Kopecká, CSc.)
  • Week 6 (21.10.-25.10.): Molecular mechanisms regulating cell cycle and cell proliferation (Mgr. Stjepan Uldrijan, CSc.)
  • Week 7 (28.10.-1.11.): Mitosis and cytokinesis in normal and cancer cells (Prof. MUDr. Marie Kopecká, CSc.)
  • Week 8 (4.11.-8.11.): Architecture, molecular biology and pathology of eukaryotic cell nucleus (Doc. MUDr. Iva Slaninová, Ph.D.)
  • Week 9 (11.11.-15.11.): Biosynthesis of proteins in eukaryotic cells (RNDr. Mário Špírek, Ph.D.)
  • Week 10 (18.11.-22.11.): Regulation of gene expression - principles and examples (Doc. MUDr. David Šmajs, Ph.D.)
  • Week 11 (25.11.-29.11.): From genotype to phenotype - introduction to molecular genetics (Doc. MUDr. David Šmajs, Ph.D.)
  • Week 12 (2.12.-6.12.): Genome instability - from molecular mechanisms of damage and DNA repair to clinical implications (doc. Mgr. Lumír Krejčí, Ph.D)
  • Week 13 (9.12.-13.12.): Cell death - mechanisms, implication for medical research (Doc. MUDr. Iva Slaninová, Ph.D.)
  • Week 14 (16.12-20.12.): Introduction to developmental biology (Prof. Ing. Petr Dvořák, CSc.)
Literature
    recommended literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
  • Essential cell biology. Edited by Bruce Alberts. 3rd ed. New York: Garland Science, 2009, 1 sv. ISBN 9780815341307. info
  • CAMPBELL, Neil A. Biologie. Edited by Jane B. Reece. Vyd. 1. Brno: Computer Press, 2006, xxxiv, 133. ISBN 8025111784. info
  • CAMPBELL, Neil A. Biology. Edited by Jane B. Reece. 7th ed. San Francisco: Pearson/Benjamin Cummings, 2005, xl, 1231. ISBN 080537146X. info
  • SNUSTAD, D. Peter, Michael J. SIMMONS, Jiřina RELICHOVÁ, Jiří DOŠKAŘ, Jiří FAJKUS, Petr HOŘÍN, Aleš KNOLL, Petr KUGLÍK, Jan ŠMARDA, Jana ŠMARDOVÁ, Renata VESELSKÁ and Boris VYSKOT. Genetika (Principles of Genetics). 1st ed. Brno: Masarykova univerzita, 2009, 894 pp. Učebnice. ISBN 978-80-210-4852-2. URL info
  • SNUSTAD, D. Peter and Michael J. SIMMONS. Principles of genetics. 5th ed. Hoboken: John Wiley & Sons, Inc, 2009, xix, 823. ISBN 9780470388259. info
  • PRITCHARD, D. J. and Bruce R. KORF. Základy lékařské genetiky. první české vydání. Praha: Galén, 2007, 182 stran. ISBN 9788072624492. info
  • HARDIN, Jeff, Gregory BERTONI and Lewis J. KLEINSMITH. Becker's world of the cell. 8th ed. Boston: Benjamin Cummings, 2012, xxviii, 79. ISBN 9780321709783. info
  • JANISCH, Roman. Overview of General Biology. 2. rozšířené. Brno: Masarykova univerzita, 2010, 91 pp. ISBN 978-80-210-5187-4. info
  • LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008, xxxvii, 11. ISBN 9780716776017. info
  • POLLARD, Thomas D., William C. EARNSHAW and Jennifer LIPPINCOTT-SCHWARTZ. Cell biology. Illustrated by Graham T. Johnson. 2nd ed. Philadelphia, Pa.: Saunders/Elsevier, 2008, xix, 905. ISBN 9780808923527. info
  • WEINBERG, Robert A. The biology of cancer. Second edition. London: Garland Science, 2013, xx, 876. ISBN 9780815345282. info
  • WOLPERT, L. Principles of development. 2nd ed. Oxford: Oxford University Press, 2002, xxv, 542. ISBN 0198792913. info
Teaching methods
lecture
Assessment methods
Lecture attendance is optional. Students continue with following subjects without proof of this semester's knowledge. Biology I (VSBI0121p) is followed by Biology II (VSBI0222p) that ends up with a written examination test. The test is based on knowledge of all topics from both semesters (lectures, seminars, practices).
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
Information on completion of the course: neukončuje se
The course is taught annually.
The course is also listed under the following terms Autumn 2000, Autumn 2001, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2014, Autumn 2015.
  • Enrolment Statistics (Autumn 2013, recent)
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