ZLBI0121p Biology I - lecture

Faculty of Medicine
Autumn 2015
Extent and Intensity
1/0. 0 credit(s). Type of Completion: -.
Teacher(s)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
prof. Ing. Petr Dvořák, CSc. (lecturer)
prof. MUDr. Marie Kopecká, CSc. (lecturer)
doc. Mgr. Lumír Krejčí, Ph.D. (lecturer)
RNDr. Pavel Krejčí, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. Augustin Svoboda, CSc., dr. h.c. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
RNDr. Mário Špírek, PhD. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
doc. Yuh-Man Wadeley, Doctor of Philosophy (lecturer)
Mgr. Hana Hříbková, Ph.D. (seminar tutor)
Mgr. Kateřina Vopěnková, Ph.D. (seminar tutor)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Tue 15:40–16:30 B11/114
Prerequisites
Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisities for studying the course. Expected knowledge for each lecture are specified in the course syllabus. Corresponding study literature is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; is able to deduce and explain the difference between healthy and pathologically-working cell; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
Syllabus
  • Week 1: 21. – 25.9. 2015
  • Introduction to medical biology - from understanding of cellular principle to modern biomedicine (prof. Ing. Petr Dvořák, CSc.)
  • Week 2: 28.9. – 2.10.
  • Basic architecture and function of eukaryotic cells (prof. MUDr. Augustin Svoboda, CSc.)
  • Week 3: 5.10. – 9.10.
  • Plasma membrane structure and function (prof. MUDr. Augustin Svoboda, CSc.)
  • Week 4: 12.10. – 16.10.
  • Molecular mechanisms of cell adhesions and intercellular communications (prof. MUDr. Augustin Svoboda, CSc.)
  • Week 5: 19.10. – 23.10.
  • Cytoskeleton and cell migration in health and disease (prof. MUDr. Marie Kopecká, CSc.)
  • Week 6: 26.10. – 30.10.
  • Mitosis and cytokinesis in normal and cancer cells (prof. MUDr. Marie Kopecká, CSc.)
  • Week 7: 2.11. – 6.11.
  • Molecular mechanisms regulating cell cycle and cell proliferation (Mgr. Stjepan Uldrijan, CSc.)
  • Week 8: 9.11. – 13.11.
  • Architecture, molecular biology and pathology of eukaryotic cell nucleus (doc. MUDr. Iva Slaninová, Ph.D.)
  • Week 9: 16.11. – 20.11.
  • Biosynthesis of proteins in eukaryotic cells (RNDr. Mário Špírek, Ph.D.)
  • Week 10: 23.11. – 27.11.
  • Regulation of gene expression - principles and examples (prof. MUDr. David Šmajs, Ph.D.)
  • Week 11: 30.11. – 4.12.
  • Cell death - mechanisms, implication for medical research (doc. MUDr. Iva Slaninová, Ph.D.)
  • Week 12: 7.12. – 11.12.
  • Introduction to developmental biology (Mgr. Vladimír Rotrekl, Ph.D.)
  • Week 13: 14.12. – 18.12.
  • Basic principles and molecular mechanisms regulating early development of mammals - physiology and pathology (Yuh-Man Wadeley, M.Sc., Ph.D.)
  • Week 14: 4.1. – 8.1. 2016
  • Substitution lecture
Literature
    required literature
  • Essential cell biology. Edited by Bruce Alberts. 3rd ed. New York: Garland Science, 2009, 1 sv. ISBN 9780815341307. info
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013, 1 online r. ISBN 9781118689028. info
  • PRITCHARD, D. J. and Bruce R. KORF. Základy lékařské genetiky. první české vydání. Praha: Galén, 2007, 182 stran. ISBN 9788072624492. info
    recommended literature
  • HARDIN, Jeff, Gregory BERTONI and Lewis J. KLEINSMITH. Becker's world of the cell. 8th ed. Boston: Benjamin Cummings, 2012, xxviii, 79. ISBN 9780321709783. info
  • LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008, xxxvii, 11. ISBN 9780716776017. info
  • SNUSTAD, D. Peter, Michael J. SIMMONS, Jiřina RELICHOVÁ, Jiří DOŠKAŘ, Jiří FAJKUS, Petr HOŘÍN, Aleš KNOLL, Petr KUGLÍK, Jan ŠMARDA, Jana ŠMARDOVÁ, Renata VESELSKÁ and Boris VYSKOT. Genetika (Principles of Genetics). 1st ed. Brno: Masarykova univerzita, 2009, 894 pp. Učebnice. ISBN 978-80-210-4852-2. URL info
  • SNUSTAD, D. Peter and Michael J. SIMMONS. Principles of genetics. 5th ed. Hoboken: John Wiley & Sons, Inc, 2009, xix, 823. ISBN 9780470388259. info
  • WEINBERG, Robert A. The biology of cancer. Second edition. London: Garland Science, 2013, xx, 876. ISBN 9780815345282. info
  • WOLPERT, L. Principles of development. 2nd ed. Oxford: Oxford University Press, 2002, xxv, 542. ISBN 0198792913. info
    not specified
  • CAMPBELL, Neil A. Biologie. Edited by Jane B. Reece. Vyd. 1. Brno: Computer Press, 2006, xxxiv, 133. ISBN 8025111784. info
  • CAMPBELL, Neil A. Biology. Edited by Jane B. Reece. 7th ed. San Francisco: Pearson/Benjamin Cummings, 2005, xl, 1231. ISBN 080537146X. info
Teaching methods
lecture
Assessment methods
Lecture attendance is optional. Students continue with following subjects without proof of this semester's knowledge. Biology I (ZLBI0121p) is followed by Biology II (ZLBI0222p) that ends up with a written examination test. The test is based on knowledge of all topics from both semesters (lectures, practices).
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
Information on completion of the course: neukončuje se
The course is taught annually.
Teacher's information
https://is.muni.cz/auth/el/1411/podzim2015/ZLBI0121p/index.qwarp
The course is also listed under the following terms Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (Autumn 2015, recent)
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