LF:aVLBI0121p Biology I - lect. - Course Information

aVLBI0121p Biology I - lecture

Extent and Intensity

1/0. 0 credit(s). Type of Completion: z (credit).

Teacher(s)

Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
prof. Ing. Petr Dvořák, CSc. (lecturer)
doc. Mgr. Lumír Krejčí, Ph.D. (lecturer)
RNDr. Pavel Krejčí, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
RNDr. Mário Špírek, PhD. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Kateřina Vopěnková, Ph.D. (lecturer)
Jana Růžičková (assistant)
Mgr. Kateřina Straková, Ph.D. (assistant)
Mgr. Martina Vráblíková (assistant)

Guaranteed by

prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Cetkovská, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine

Timetable

Thu 11:30–12:20 B11/334

Prerequisites

Knowledge of high-school biology on the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/anim/overview_ENG.qwarp) or similar, and knowledge of all previous lectures and practical classes of the subject. Expected knowledge for each lecture is specified in the course syllabus. Literature recomended to study before each lecture is detailed in the interactive syllabus of the course.

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• General Medicine (eng.) (programme LF, M-VL)
• General Medicine (programme LF, M-VL) (2)

Course objectives

After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; knows basic principles of bacterial and viral diseases; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects, and understands the principle of genetic determination of hereditary diseases; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.

Syllabus

• Week 1:
• Introduction to medical biology - from understanding of cellular principle to modern biomedicine (prof. Ing. Petr Dvořák, CSc.)
• Week 2:
• Bacteria and viruses – characteristics, reproduction strategies and principles of treatment (Mgr. Kateřina Vopěnková, Ph.D.)
• Week 3:
• Structure, functions and function anomalies of eukaryotic cells (Mgr. Kateřina Cetkovská, Ph.D.)
• Week 4:
• Cells in the context of the entire organism – principles of cell adhesion and intercellular communication (Mgr. Kateřina Cetkovská, Ph.D.)
• Week 5:
• Cell signalling and the principle of cell differentiation (Mgr. Kateřina Vopěnková, Ph.D.)
• Week 6:
• Cell death – mechanisms and regulation of apoptosis and its significance for medicine (doc. MUDr. Iva Slaninová, Ph.D.)
• Week 7:
• The importance of genetic information – the journey from a gene to protein; DNA replication (RNDr. Mário Špírek, Ph.D.)
• Week 8:
• Cell cycle – molecular mechanisms of regulation and significance for oncology (Mgr. Stjepan Uldrijan, CSc.)
• Week 9:
• Mitotic division in normal and cancer cells (Mgr. Vladimír Rotrekl, Ph.D.)
• Week 10:
• dissection week - no lecture
• Week 11:
• Meiosis and the principle of genetic variability (Mgr. Vladimír Rotrekl, Ph.D.)
• Week 12:
• The basics of genetics, the nature of dominance and recessivity (Mgr. Kateřina Vopěnková, Ph.D.)
• Week 13:
• Genetics of human diseases – molecular principles of genetically determined disorders (doc. MUDr. Iva Slaninová, Ph.D.)
• Week 14:
• Epigenetics – the link between genes and environment (Mgr. Stjepan Uldrijan, CSc.)
• Week 15:
• substitution lecture

Literature

required literature
• ALBERTS, Bruce. Essential cell biology. 4th edition. New York, N.Y.: Garland Science, 2014, xxiii, 726. ISBN 9780815344551. info
• Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013, 1 online r. ISBN 9781118689028. info

recommended literature
• HARDIN, Jeff, Gregory BERTONI and Lewis J. KLEINSMITH. Becker's world of the cell. 8th ed. Boston: Benjamin Cummings, 2012, xxviii, 79. ISBN 9780321709783. info
• LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008, xxxvii, 11. ISBN 9780716776017. info
• SNUSTAD, D. Peter and Michael J. SIMMONS. Principles of genetics. 5th ed. Hoboken: John Wiley & Sons, Inc, 2009, xix, 823. ISBN 9780470388259. info
• WEINBERG, Robert A. The biology of cancer. Second edition. London: Garland Science, 2013, xx, 876. ISBN 9780815345282. info
• WOLPERT, L. Principles of development. 2nd ed. Oxford: Oxford University Press, 2002, xxv, 542. ISBN 0198792913. info

not specified
• CAMPBELL, Neil A. Biology. Edited by Jane B. Reece. 7th ed. San Francisco: Pearson/Benjamin Cummings, 2005, xl, 1231. ISBN 080537146X. info

Teaching methods

lecture

Assessment methods

Lecture attendance is optional. Students continue with following subjects without proof of this semester's knowledge. Biology I (aVLBI0121p) is followed by Biology II (aVLBI0222p) that is completed with a written examination test. The test is based on knowledge of all topics from both semesters (lectures, seminars, practices).

Language of instruction

English

Follow-Up Courses

• aVLBI0222p Medical Biology II - lecture

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

https://is.muni.cz/auth/el/1411/podzim2016/aVLBI0121p/index.qwarp

• Enrolment Statistics (Autumn 2016, recent)
  
• Permalink: https://is.muni.cz/course/med/autumn2016/aVLBI0121p