LF:MBLG071c Medical genetics - practices - Course Information

MBLG071c Medical genetics - practices

Extent and Intensity

0/1/0. 1 credit(s). Type of Completion: z (credit).

Teacher(s)

prof. MUDr. Michael Doubek, Ph.D. (lecturer)
RNDr. Iveta Valášková, Ph.D. (lecturer)
MUDr. Renata Gaillyová, Ph.D. (lecturer)
Mgr. Marta Navaříková (lecturer)
Mgr. Hana Filková (lecturer)
prof. RNDr. Mgr. Marie Jarošová, CSc. (lecturer)
MUDr. Jana Šoukalová (lecturer)
MUDr. Rastislav Beharka (lecturer)
Mgr. Iva Synková, Ph.D. (lecturer)
prof. RNDr. Jana Šmardová, CSc. (lecturer)
Bc. Kateřina Stehlíková, DiS. (assistant)

Guaranteed by

RNDr. Iveta Valášková, Ph.D.
Institute of Medical Genetics and Genomics – Institutions shared with the Faculty Hospital Brno (paediatric medicine) – Faculty of Medicine
Contact Person: Bc. Kateřina Stehlíková, DiS.
Supplier department: Institute of Medical Genetics and Genomics – Institutions shared with the Faculty Hospital Brno (paediatric medicine) – Faculty of Medicine

Timetable

Fri 9. 10. 9:00–11:30 342, Fri 16. 10. 9:00–11:30 342, Fri 23. 10. 9:00–11:30 342, Fri 30. 10. 9:00–11:30 342, Fri 6. 11. 9:00–11:30 342, Fri 13. 11. 9:00–11:30 342, Fri 20. 11. 9:00–11:30 342, Fri 27. 11. 9:00–11:30 342, Fri 4. 12. 9:00–11:30 342, Fri 11. 12. 9:00–11:30 342, Fri 15. 1. 9:00–11:30 342, Fri 22. 1. 9:00–11:30 342

Prerequisites

completed undergraduate studies (disciplines: biology, molecular biology, biochemistry etc.)

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Bioanalytical Laboratory Diagnostics in Medicine - Bioanalyst (programme PřF, N-BIA)

Course objectives

The course acquaints students with basic knowledge in the field of clinical genetics. The aim is to get a basic overview of clinical genetics, to learn the basic rules of inheritance of signs and diseases, to outline the basics of applied genetics in medicine. To get a basic overview of clinical cytogenetics and molecular cytogenetics. To obtain a basic overview of DNA diagnostics of serious inherited diseases.

Learning outcomes

Upon completion of the course the student will be able to join the laboratory teams of clinical genetics. The acquired knowledge and practical skills will be able to apply in the laboratory procedures in cytogenetics and molecular cytogenetics, including DNA analysis techniques.

Syllabus

• Preparation and evaluation of cytogenetic preparations for prenatal cytogenetic diagnostics, chorionic treatment, amniotic fluid. Preparation and evaluation of preparations for postnatal cytogenetic diagnosis - peripheral and fetal blood lymphocytes. The use of molecular cytogenetic methods in clinical cytogenetics (FISH, M-FISH, array-CGH) Long-term cultivation for cytogenetic examination. Isolation, processing and storage of DNA / RNA in the diagnosis of hereditary diseases. Direct and indirect DNA analysis. PCR, electrophoresis, screening methods in DNA diagnostics, fragmentation analysis, sequencing of human DNA in the diagnosis of hereditary diseases. Use of DNA analysis in the prenatal diagnosis of serious hereditary diseases.

Literature

• Dopl.

Teaching methods

Performance, writing and evaluation of the laboratory task. Consulation of findings with the teacher

Assessment methods

Credits are granted for active participation, attendance and writing of quality protocols of individual tasks.

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
Information on the extent and intensity of the course: 15.

• Enrolment Statistics (autumn 2020, recent)
  
• Permalink: https://is.muni.cz/course/med/autumn2020/MBLG071c