MRBC0111p Biochemistry - lecture

Faculty of Medicine
autumn 2023
Extent and Intensity
2/0/0. 2 credit(s). Type of Completion: zk (examination).
Teacher(s)
RNDr. Hana Paulová, CSc. (lecturer)
Mgr. Jiří Slanina, Ph.D. (lecturer)
doc. RNDr. Jiří Dostál, CSc. (assistant)
prof. RNDr. Eva Táborská, CSc. (assistant)
doc. RNDr. Josef Tomandl, Ph.D. (assistant)
Mgr. Marie Tomandlová, Ph.D. (assistant)
MUDr. Michaela Králíková, Ph.D. (alternate examiner)
Guaranteed by
RNDr. Hana Paulová, CSc.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Contact Person: RNDr. Hana Paulová, CSc.
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Timetable
Mon 30. 10. to Fri 22. 12. Tue 17:00–18:50 B22/116 aula, Mon 18. 9. to Fri 20. 10. Tue 17:00–18:50 B22/116 aula; and Tue 24. 10. 17:00–18:50 B11/334
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Biochemistry for bacherols follows secondary school chemistry and biochemistry broadens the subject considerably to the level required for the study of successive subjects. The aim of the subject is to provide a comprehensive view of the basic metabolic processes in the human body related to the functioning of the human organism. It gets information on the production and use of energy in the human body, the structure and synthesis of the main molecules, the main regulatory mechanisms that maintain homeostasis. Students will obtain knowledge about the biochemical nature of the most important disorders of metabolism and bases of their clinico-biochemical examination, taking into account their specialization.
Learning outcomes
After the completition of the subject student will understand physico-chemical processes important for biological systems, He is able to
- explain basic principles of nutrient metabolism,
- discuss the principles of regulation,
- understand how energy is generated, used, and stored by the various organs of the body,
- describe the biochemical proceses typical for main organs and tissues in the body (heart, liver, kidney muscle, nerve tissue),
- explain basic principles of homeostasis,
- characterize the composition and function of the main body fluids,
- understand the processes of hemocoagulation.
He is familiar with the effects of major hormones and the principle of their action through receptors.
Syllabus
  • Basic terms. Solutions, concentration. Elektrolytes. Osmotic pressure. Acids and bases, pH. Buffers.
  • Biogenic elements – overview, significance. Toxic elements.
  • Biochemically important organic substances.
  • Surfactans.
  • Saccharides-properties, classifications, overview.
  • Amino acids, peptides, proteins – properties, classification, overview.
  • Enzymes-structures, mechanism of enzymatic action, overview. Enzymes important in clinical biochemistry.
  • Lipides- properties, classifications, overview. Steroids-overview. Cholesterol, bile pigments.
  • Vitamins.
  • Nukleosides a nukleotides, basic types of nucleic acids.
  • Replication, transcription, translation.
  • Membranes, transport.
  • Metabolismus of nutrients-overview. Production of energy in cell.
  • Digestion and resorption of saccharides. Metabolism of saccharides.
  • Proteins in food, digestion, resorption. Metabolism of proteins and amino acids.
  • Digestion and resorption of lipids. Lipoproteins. Metabolism of lipids. Metabolism of cholesterol.
  • Metabolism under different states.
  • Biochemistry of blood.
  • Degradation of blood pigment.
  • Management of water and ions in the body.
  • Acid-base balance in organism.
  • Biochemical function of liver, kidneys. Muscle tissue biochemistry. Connective tissue biochemistry.
  • Signal molecules and receptors.
  • Nerve cell. Nerve signal transmittion.
  • Biochemistry of vision.
Literature
Teaching methods
Teaching form are lectures, 2 hours per week.
Assessment methods
Written examination. The test is solved on computers in the computer room of the Department of Biochemistry. Detailed information is published in IS MUNI (Study materials-Course-related instruction).
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
Information on the extent and intensity of the course: 30.
The course is also listed under the following terms Autumn 2016, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2024.
  • Enrolment Statistics (autumn 2023, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2023/MRBC0111p