VSBI0222p Biology II - lecture

Faculty of Medicine
Spring 2013
Extent and Intensity
1/3/0. 4 credit(s). Recommended Type of Completion: zk (examination). Other types of completion: RZk (examination).
Teacher(s)
prof. Ing. Petr Dvořák, CSc. (lecturer)
prof. MUDr. Marie Kopecká, CSc. (lecturer)
doc. Mgr. Lumír Krejčí, Ph.D. (lecturer)
RNDr. Pavel Krejčí, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. Augustin Svoboda, CSc., dr. h.c. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
doc. Yuh-Man Wadeley, Doctor of Philosophy (lecturer)
Mgr. Hana Hříbková, Ph.D. (seminar tutor)
Mgr. Kateřina Vopěnková, Ph.D. (seminar tutor)
Eva Skalová (assistant)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Mon 8:30–9:20 B22/116 aula
  • Timetable of Seminar Groups:
VSBI0222p/VLA: Wed 15:00–15:50 B11/234
Prerequisites (in Czech)
VSBI0121c Biology I-pract. && ZC011 Handling chemical substances
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The course provides an overview of the current knowledge of molecular biology, genetics and human genetics in the context of other theoretical branches of the Faculty of Medicine. Recent concepts of developmental biology and ontogeny, cell signalling, structural and epigenetic changes in the DNA, cancer biology, gene therapy and bioinformatics are discussed. The subject matter presented in this course will help to better understanding of other subjects including physiology, pathology and human and clinical genetics.
Syllabus
  • 1st week: 18.-22.2. 2013 Lecture: Introduction to developmental biology 2nd week: 25.2. – 1.3.2013 Lecture: Basic principles and molecular mechanisms regulating early development of mammals – physiology and pathology 3rd week: 4. – 8.3.2013 Lecture: Biology and use of stem cells in disease modelling and cell therapy 4th week: 11. – 15.3.2013 Lecture: Growth factors and signal transduction in development and disease 5th week: 18. – 22.3.2013 Lecture: Genome instability - from molecular mechanisms of damage and DNA repair to clinical implications 6th week: 25. – 29.3.2013 Lecture: Molecular principle of genetic diseases 7th week: 1. – 5.4.2013 Lecture: Introduction to cancer biology 8th week: 8. – 12.4.2013 Lecture: Oncogenes and oncoviruses in cancer transformation 9th week: 15. – 19.4.2013 Lecture: Tumour supressor genes – implications for diagnostics and therapy 10th week: 22. – 26.4.2013 Lecture: Paradigm of cancer stem cells 11th week: 29.4. – 3.5.2013 Lecture: Objectives and strategies of molecular therapy 12th week: 6. – 10.5.2013 Lecture: Bioinformatics in medicine – from molecules to populations 13th week: 13. – 17.5.2013 Lecture: Milestones in biological sciences in context with advances in clinical medicine 14th week: 20. – 24.5.2013 Lecture: Advances in molecular, cell or developmental biology with regard to biomedicine - „Breakthrough of the Year 2012“
Literature
    recommended literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
  • Essential cell biology. Edited by Bruce Alberts. 3rd ed. New York: Garland Science, 2009, 1 sv. ISBN 9780815341307. info
  • CAMPBELL, Neil A. Biologie. Edited by Jane B. Reece. Vyd. 1. Brno: Computer Press, 2006, xxxiv, 133. ISBN 8025111784. info
  • CAMPBELL, Neil A. Biology. Edited by Jane B. Reece. 7th ed. San Francisco: Pearson/Benjamin Cummings, 2005, xl, 1231. ISBN 080537146X. info
  • SNUSTAD, D. Peter, Michael J. SIMMONS, Jiřina RELICHOVÁ, Jiří DOŠKAŘ, Jiří FAJKUS, Petr HOŘÍN, Aleš KNOLL, Petr KUGLÍK, Jan ŠMARDA, Jana ŠMARDOVÁ, Renata VESELSKÁ and Boris VYSKOT. Genetika (Principles of Genetics). 1st ed. Brno: Masarykova univerzita, 2009, 894 pp. Učebnice. ISBN 978-80-210-4852-2. URL info
  • SNUSTAD, D. Peter and Michael J. SIMMONS. Principles of genetics. 5th ed. Hoboken: John Wiley & Sons, Inc, 2009, xix, 823. ISBN 9780470388259. info
  • PRITCHARD, D. J. and Bruce R. KORF. Základy lékařské genetiky. první české vydání. Praha: Galén, 2007, 182 stran. ISBN 9788072624492. info
  • HARDIN, Jeff, Gregory BERTONI and Lewis J. KLEINSMITH. Becker's world of the cell. 8th ed. Boston: Benjamin Cummings, 2012, xxviii, 79. ISBN 9780321709783. info
  • JANISCH, Roman. Overview of General Biology. 2. rozšířené. Brno: Masarykova univerzita, 2010, 91 pp. ISBN 978-80-210-5187-4. info
  • LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008, xxxvii, 11. ISBN 9780716776017. info
  • Pollard, Thomas D., Earnshaw, William C.: Cell Biology, 2nd edition, Saunders 2007. ISBN: 978-1-4160-2255-8
  • WOLPERT, L. Principles of development. 2nd ed. Oxford: Oxford University Press, 2002, xxv, 542. ISBN 0198792913. info
Teaching methods
lecture
Assessment methods
written test - valid ICIS card is required to prove personal identity
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2014, Spring 2015, Spring 2016.
  • Enrolment Statistics (Spring 2013, recent)
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