LF:aZLBI0222c Biology II -practice

aZLBI0222c Biology II - practice

Faculty of Medicine
Spring 2018

Extent and Intensity

0/2. 2 credit(s). Type of Completion: z (credit).

Teacher(s)

Guaranteed by

prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine

Timetable

Wed 14:10–15:50 B07/214

Prerequisites (in Czech)

( aZLBI0121c Biology I - pract. || ZLBI0121c Biology I - pract. ) && ( aZC011 Handling chemical substances || ZC011 Handling chemical substances )

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

Dentistry (eng.) (programme LF, M-ZL)
Dentistry (programme LF, M-ZL) (2)

Course objectives

The main objectives of the course are:
- learning the methods of risk evaluation for hereditary diseases of various molecular background in patients based on family anamneses
- understanding the basic principles of gene engineering
- understanding and practicing the selected molecular methods used for examination of some cancers or hereditary and infectious diseases with regard to selection of appropriate therapy

Learning outcomes

After completing the course the student will be able to:
- evaluate the risk of hereditary diseases of various molecular background in patients based on assigned family anamneses of the diseases
- describes the basic principles of genetic prognosis and genetic counselling
- suggest and perform basic molecular-genetic diagnostic examinations of some hereditary, tumour and infectious diseases (PCR, restriction digest, gel electrophoresis), and to interpret the obtained results
- explain selected basic techniques of gene engineering and their application in medicine, and, with knowledge of the used method, to select the clones of cells with an inserted gene
- explain the basic laboratory tests used in genetic toxicology and the overall use of genetic toxicology, and to interpret the results obtained by selected methods

Syllabus

Week 1: Genetic disorders - gonosomal inheritance
Week 2: Deviations from Mendelian genetics
Week 3: Genetic prognosis and genetic counselling
Week 4: Human population genetics
Week 5: Control test 3 (knowledge from week 13 of the autumn semester to week 4 of the spring semester - lectures, practices)
Week 6: Molecular diagnostics of cancer with respect to treatment options
Week 7: Gene engineering – production of human proteins in bacterial cells
Week 8: Molecular analysis of disease predispositions in humans
Week 9: Molecular diagnostics of human pathogenic bacteria
Week 10: Restriction mapping of DNA
Week 11: Genetic toxicology
Week 12: substitution practices – substitutions for public holidays
Week 13: Control test 4 (knowledge from week 5 to week 12 of the spring semester - lectures, practices)
Week 14: Re-sit tests 3 and 4
Week 15: credit awarding

Literature

required literature

Protocols for practices are provided in electronic form in the Information System of the Masaryk University in the Study Materials of the course aZLBI0222c

Teaching methods

laboratory practice, class discussion

Assessment methods

Practical classes are mandatory.
Requirements for course completion: full attendance in the practices (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and checked and signed by appropriate teachers; successfully passed 2 written control tests during the semester (20 questions each, 4 possibilities, 1 answer correct, student need to reach at least 12 points out of 20 in each test). In case you do not pass one of the control tests and its re-sit, you have to pass the final test (so-called Credit test) based on knowledge of the entire semester lectures and practices. The test comprises of 20 questions: 10 test questions (multiple answers can be correct, negative marking is obtained for incorrect answers) + 10 given terms for written explanation. At least 10 points out of 20 are needed to pass.
In case of student’s late arrival to the practice or poor activity at the practice, the student is required to write an essay in the length of 2 pages on a given topic. Same for the case of 2nd and any additional absence in practices (excused or unexcused). Find the instructions for essay writing in the Course-related instructions in the IS, bring the essay printed to the teacher who specified the topic and be ready to answer the teacher's questions regarding the topic.
In case of 3 absences, (or more than 3 absences all excused by the Office for Studies within 5 days from the beginning of the absence and introduced to the Information System), it is addressed individually and course-unit credit is awarded only after the proof of the student's knowledge of the entire semester topics (Credit test, see above).
In case of 4 or more unexcused absences, course-unit credit is not awarded.

Language of instruction

English

Follow-Up Courses

Further comments (probably available only in Czech)

The course is taught annually.

Listed among pre-requisites of other courses

Teacher's information

https://is.muni.cz/auth/el/1411/jaro2018/aZLBI0222c/index.qwarp

The course is also listed under the following terms Spring 2016, Spring 2017, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024, spring 2025.

Enrolment Statistics (Spring 2018, recent)
Permalink: https://is.muni.cz/course/med/spring2018/aZLBI0222c

LF:aZLBI0222c Biology II -practice - Course Information

aZLBI0222c Biology II - practice

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