VLTZ0451 Theoretical Bases of Clinical Medicine I - seminar

Faculty of Medicine
spring 2020
Extent and Intensity
0/1.5/0. 2 credit(s). Type of Completion: z (credit).
Teacher(s)
prof. PharmDr. Petr Babula, Ph.D. (seminar tutor)
Mgr. Tomáš Bárta, Ph.D. (seminar tutor)
doc. MUDr. Markéta Bébarová, Ph.D. (seminar tutor)
prof. Ing. Petr Dvořák, CSc. (seminar tutor)
doc. MVDr. Aleš Hampl, CSc. (seminar tutor)
MUDr. Michal Jurajda, Ph.D. (seminar tutor)
prof. MUDr. Kateřina Kaňková, Ph.D. (seminar tutor)
prof. MUDr. Marta Krejčí, Ph.D. (seminar tutor)
doc. MUDr. Milan Krtička, Ph.D. (seminar tutor)
doc. MUDr. Leoš Křen, Ph.D. (seminar tutor)
MUDr. Petr Lokaj, Ph.D. (seminar tutor)
prof. MUDr. Robert Mikulík, Ph.D. (seminar tutor)
MUDr. Martin Pešl, Ph.D. (seminar tutor)
Mgr. Vladimír Rotrekl, Ph.D. (seminar tutor)
doc. MUDr. Veronika Slonková, Ph.D. (seminar tutor)
prof. MUDr. Anna Vašků, CSc. (seminar tutor)
doc. MUDr. Lenka Veverková, Ph.D. (seminar tutor)
Jarmila Jelínková (assistant)
Věra Ježková (assistant)
Guaranteed by
doc. MUDr. Leoš Křen, Ph.D.
Department of Pathology – Joint workplaces with the University Hospital Brno - workplaces of the Bohunice and Mater. Hospital – Faculty of Medicine
Supplier department: First Department of Surgery – Institutions shared with St. Anne's Faculty Hospital – Faculty of Medicine (7,00 %), First Department of Dermatovenerology – Institutions shared with St. Anne's Faculty Hospital – Faculty of Medicine (13,00 %), Department of Internal Medicine, Hematology and Oncology – Joint workplaces with the University Hospital Brno - workplaces of the Bohunice and Mater. Hospital – Faculty of Medicine (13,00 %), Department of Biology – Theoretical Departments – Faculty of Medicine (13,00 %), Department of Physiology – Theoretical Departments – Faculty of Medicine (20,00 %), Department of Histology and Embryology – Theoretical Departments – Faculty of Medicine (13,00 %), Department of Pathophysiology – Theoretical Departments – Faculty of Medicine (21,00 %)
Timetable
Fri 15:00–16:40 B22/116 aula
Prerequisites (in Czech)
VLFY0321c Physiology I - practice && VLFY0321s Physiology I - seminar && VLBC0321s Biochemistry I sem && VLBC0321c Biochemistry I && VLBI0222p Biology II-lect. && VLAN0222c Anatomy II p && VLAN0222s Anatomy II s
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
This newly introduced subject focuses on overview exercising of substantial problems from the point of view of anatomist, embryologist, physiologist, pathological physiologist, pathologist, microbiologist, immunologist and finally, corresponding clinician. Using this approach we will conceptually approach closer to strategy of USMLE, Step 1.
Learning outcomes (in Czech)
Student bude po absolvování předmětu schopen porozumět a vysvětlit základní pojmy týkající se regenerace a reparace lidských tkání. Chápe pojem kmenová buňka a rozumí jejich roli v procesu hojení ran. Dále se student orientuje v problematice metabolismu vápníku v lidském těle, jeho významu a regulacích jeho hladiny v těle. Vyjmenuje a vysvětlí princip laboratorních vyšetřeních používaných při sledování metabolismu vápníku.
Syllabus
  • Stem cells, wound healing, regeneration in medicine Guarantor of topic: doc. MVDr. Aleš Hampl, CSc. 1. Importance and perspectives od stem cells application in medicine I (2 hrs, , MUDr. Martin Pešl, Ph.D.; Mgr. Vladimír Rotrekl, Ph.D.) 2. Importance and perspectives od stem cells application in medicine II (2 hrs, doc. Hampl) 3. Wound healing in dermatology (2 hrs, dr. Slonková) 4. Autologous and allogenic hematopoietic stem cells transplantation: introduction, contemporary indications and trends (2 hrs, prof. M. Krejčí) 5. Possibilities of using of cardiomyocytes produced by induced pluripotent stem cells of individual patient i medicine (1 hr, doc. Bébarová) Wound healing in surgery (1 hr, doc. Veverková) Metabolic bone diseases Guarantor of topic: prof. MUDr. Anna Vašků, CSc. 6. Osteoporosis, osteodystrophy, and osteomalacia: Bone state in patients with chronic renal failure: pathophysiological point of view (2 hrs, prof. A. Vašků) 7. Metabolism of calcium and phosphates (1 hr, doc. Babula) Laboratory diagnostics (Ca, phosphates, PTH, PTHrP, vitamin D, paraproteins) – 1 hr, doc. Babula) 8. Clinical example (woman aged 85, living alone with pathophysiological fracture history)- (1 hr, prof. A. Vašků) 9. Easter Molecularbiology concepts in oncogenesis Guarantor of topic: prof. MUDr. Anna Vašků, CSc. 10. Concept of „Read and Write“ genome and consequences of its application in oncology (prof. A.Vašků, 2 hrs) 11. Importance of epigenetics in oncology (prof. Slabý; 1.5 hr) 12. „Next generation sequencing“ in oncology (doc. Mráz, 2 hrs) 13. Importance of cytogenetics in hematological malignancies (doc. Ševčíková, 2 hrs) 14. EXAM TEST
Literature
    recommended literature
  • SILBERNAGL, Stefan and Florian LANG. Color atlas of pathophysiology. 3rd edition. Stuttgart: Thieme, 2016, x, 438. ISBN 9783131165534. info
  • PORTH, Carol. Essentials of pathophysiology : concepts of altered health states. Edited by Kathryn J. Gaspard - Kim A. Noble. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2010, xxiv, 1256. ISBN 9781451103182. info
  • DAMJANOV, Ivan. Pathophysiology. Illustrated by Matthew Chansky. 1st ed. Philadelphia: Saunders/Elsevier, 2009, vii, 464. ISBN 9781416002291. info
Teaching methods
Education will be realised by interactive seminars, practicals and lections.
Assessment methods
Written test at the end of each semester.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 22.5.
The course is also listed under the following terms Spring 2018, spring 2019, spring 2021, spring 2023.
  • Enrolment Statistics (spring 2020, recent)
  • Permalink: https://is.muni.cz/course/med/spring2020/VLTZ0451