aZLFA0621p Pharmacology I - lecture

Faculty of Medicine
spring 2021
Extent and Intensity
1/0/0. 1 credit(s). Type of Completion: z (credit).
Teacher(s)
doc. MUDr. Regina Demlová, Ph.D. (lecturer)
doc. PharmDr. Jan Juřica, Ph.D. (lecturer)
Mgr. Petra Amchová, Ph.D. (lecturer)
doc. RNDr. Ladislava Bartošová, Ph.D. (lecturer)
Mgr. Jana Kubátová, Ph.D. (lecturer)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (lecturer)
MUDr. Jana Nováková, Ph.D. (lecturer)
MUDr. Jana Pistovčáková, Ph.D. (lecturer)
doc. PharmDr. Jana Rudá, Ph.D. (lecturer)
PharmDr. Jitka Rychlíčková, Ph.D. (lecturer)
Mgr. Barbora Říhová, Ph.D. (lecturer)
PharmDr. Lenka Součková, Ph.D. (lecturer)
prof. MUDr. Dalibor Valík, Ph.D., DABCC (lecturer)
prof. RNDr. Lenka Zdražilová Dubská, Ph.D. (lecturer)
Renata Bláblová (assistant)
Květoslava Sedlářová (assistant)
Mgr. Martin Brož (alternate examiner)
Mgr. Kateřina Nebeská (alternate examiner)
Mgr. Kristýna Nosková, Ph.D. (alternate examiner)
Guaranteed by
doc. MUDr. Regina Demlová, Ph.D.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: doc. MUDr. Regina Demlová, Ph.D.
Supplier department: Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Timetable
Tue 2. 3. 7:00–8:40 A19/229, Tue 9. 3. 7:00–8:40 A19/229, Tue 16. 3. 7:00–8:40 A19/229, Tue 23. 3. 7:00–8:40 A19/229, Tue 30. 3. 7:00–8:40 A19/229, Tue 6. 4. 7:00–8:40 A19/229, Tue 13. 4. 7:00–8:40 A19/229, Tue 20. 4. 7:00–8:40 A19/229
Prerequisites (in Czech)
aZLPA0521c Pathology I - practice && aZLPF0521c Pathophysiol. I - practice && aZLCP051c Clin. Introd. in Surgery-prac.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
At the end of the course, the student should be able to understand integration in the field of biomedical sciences such as chemistry, physiology, molecular biology, pathology and pathological physiology clarifying mechanisms of drugs effects and under which conditions they may elicit therapeutic, adverse, and toxic effects. Students will be familiar with principles of pharmacovigilance.
Learning outcomes
At the end of the course student will be able:
- to understand integration in the field of biomedical sciences such as chemistry, physiology, molecular biology, pathology and pathological physiology clarifying mechanisms of drugs effects and under which conditions they may elicit therapeutic, adverse, and toxic effects, and what is the relation to the dose given and route of administration.
- to undertstand the principles of pharmacovigilance.
Syllabus

  • LECTURES

  • Spring semester 2021

  • 1st week
  • Historical aspects of pharmacology. Pharmacology - definitions, terminology, subspecializations. The active substance, pharmacon - drug. Effective pharmacotherapy.
  • 2nd week
  • Pharmacodynamics. Mechanisms of drug action, non-specific, specific. Receptor and binding sites subtypes, their function.
  • 3rd week
  • Drug delivery approaches. Classification of administration routes. Factors related to administration route selection. Characteristic of administration routes. Innovative administration routes.
  • 4th week
  • Pharmacokinetics. Drug absorption, distribution, metabolism and elimination. Changes of drug effects after the repeated administration.
  • 5th week
  • General principles of poisoning management. Specific antidotes in poisoning therapy. General principles of drug addiction.
  • 6th week
  • Drug addiction to the individual substances.
  • 7th week
  • H1 antihistamines, antiasthmatics Classification and clinical use of H1 antihistamines. Pathophysiology of bronchial asthma, sites and mechanisms of action of antiasthma drugs.
  • 8th week
  • Antidepressant drugs. Classification, mechanisms of action, adverse effects.
Literature
    required literature
  • RANG, H. P., James RITTER, R. J. FLOWER and Graeme HENDERSON. Rang & Dale's pharmacology. Eighth edition. [Edinburgh]: Churchill Livingstone, 2016, xv, 760. ISBN 9780702053627. info
  • http://search.ebscohost.com/login.aspx?direct=true&db=nlebk&AN=1160493&lang=cs&site=ehost-live
  • Selected chapters from general pharmacology for students of general medicine and dentistry at FM MU, https://portal.med.muni.cz/discipline-13-pharmacology
    recommended literature
  • WHALEN, Karen. Pharmacology. Edited by Richard Finkel - Thomas A. Panavelil. 6th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins, 2015, xi, 664. ISBN 9781451191776. info
    not specified
  • Pharmaceutical practice. Edited by Judith A. Rees - Ian Smith - Jennie Watson. 5th ed. Edinburgh: Churchill Livingstone Elsevier, 2014, xvii, 552. ISBN 9780702051432. info
  • Waller, Derek - Renwick, Andrew G. - Hillier, Keith. Medical pharmacology and therapeutics. 3rd ed. New York : Elsevier Saunders, 2009. ix, 744 p. ISBN 0-7020-2991-2.
Teaching methods
Students are expected to follow the provided lectures.
Assessment methods
There is no testing of knowledge in this part of study as students are expected to continue pharmacological course in the subsequent semester.
Language of instruction
English
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 15.
Teacher's information
Information for the students:

Termination in the Spring semester: credit.

There is no testing of knowledge in this part of study.

Office hours of the secretariat of the Department of Pharmacology, Faculty of Medicine, Masaryk University, Kamenice 5, 625 00 Brno - Bohunice:

daily 13.00 - 14.00 pm, tel.: 05-4949 3070.

The course is also listed under the following terms Spring 2018, spring 2019, spring 2020, spring 2022, spring 2023, spring 2024, spring 2025.
  • Enrolment Statistics (spring 2021, recent)
  • Permalink: https://is.muni.cz/course/med/spring2021/aZLFA0621p