ZLBI0222c Biology II - practice

Faculty of Medicine
spring 2024
Extent and Intensity
0/2/0. 1 credit(s). Type of Completion: z (credit).
Teacher(s)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (lecturer)
Mgr. Kateřina Francová, Ph.D. (lecturer)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
Mgr. Kateřina Straková, Ph.D. (lecturer)
Mgr. Andrej Bešše, Dr. sc. nat. (seminar tutor)
Mgr. Lenka Bešše, Ph.D. (seminar tutor)
Mgr. Anna Dorotíková (seminar tutor)
Mgr. Filip Kafka (seminar tutor)
Mgr. Kateřina Koždoňová (seminar tutor)
Mgr. Bc. Karolína Smolková (seminar tutor)
Ing. Natália Vadovičová (seminar tutor)
RNDr. Mgr. Eliška Vrbová, Ph.D. (seminar tutor)
Jana Růžičková (assistant)
Guaranteed by
prof. MUDr. Iva Slaninová, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Francová, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable of Seminar Groups
ZLBI0222c/21: Tue 20. 2. 10:00–10:30 B07/205a, 10:30–11:30 B07/205a, 10:30–11:30 B07/217, 11:30–11:40 B07/205a, Tue 27. 2. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 5. 3. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 12. 3. 10:00–10:30 B07/205a, 10:30–11:30 B07/205a, 10:30–11:30 B07/217, 11:30–11:40 B07/205a, Tue 19. 3. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 26. 3. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 2. 4. 10:00–10:30 B07/205a, 10:30–11:30 B07/205a, 10:30–11:30 B07/217, 11:30–11:40 B07/205a, Tue 9. 4. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 16. 4. 10:00–10:30 B07/205a, 10:30–11:30 B07/205a, 10:30–11:30 B07/217, 11:30–11:40 B07/205a, Tue 23. 4. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 30. 4. 10:00–10:30 B07/205a, 10:30–11:30 B07/205a, 10:30–11:30 B07/217, 11:30–11:40 B07/205a, Tue 7. 5. 10:00–10:30 B07/205a, 10:30–11:30 B07/205a, 10:30–11:30 B07/217, 11:30–11:40 B07/205a, Tue 14. 5. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 21. 5. 10:00–10:30 B07/205a, 10:30–11:30 B07/205a, 10:30–11:30 B07/217, 11:30–11:40 B07/205a
ZLBI0222c/22: Tue 20. 2. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 27. 2. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 5. 3. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 12. 3. 10:00–10:30 B07/205a, 10:30–11:30 B07/205a, 10:30–11:30 B07/217, 11:30–11:40 B07/205a, Tue 19. 3. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 26. 3. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 2. 4. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 9. 4. 10:00–10:30 B07/205a, 10:30–11:30 B07/205a, 10:30–11:30 B07/217, 11:30–11:40 B07/205a, Tue 16. 4. 10:00–10:30 B07/205a, 10:30–11:30 B07/205a, 10:30–11:30 B07/217, 11:30–11:40 B07/205a, Tue 23. 4. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 30. 4. 10:00–10:30 B07/205a, 10:30–11:30 B07/217, 10:30–11:30 B07/205a, 11:30–11:40 B07/205a, Tue 7. 5. 10:00–10:30 B07/205a, 10:30–11:30 B07/205a, 10:30–11:30 B07/217, 11:30–11:40 B07/205a, Tue 14. 5. 10:00–10:30 B07/205a, 10:30–11:30 B07/205a, 10:30–11:30 B07/217, 11:30–11:40 B07/205a, Tue 21. 5. 10:00–10:30 B07/205a, 10:30–11:30 B07/205a, 10:30–11:30 B07/217, 11:30–11:40 B07/205a
ZLBI0222c/23: Wed 21. 2. 11:30–12:00 B07/205a, 12:00–13:00 B07/205a, 12:00–13:00 B07/217, 13:00–13:10 B07/205a, Wed 28. 2. 11:30–12:00 B07/205a, 12:00–13:00 B07/205a, 12:00–13:00 B07/217, 13:00–13:10 B07/205a, Wed 6. 3. 11:30–12:00 B07/205a, 12:00–13:00 B07/217, 12:00–13:00 B07/205a, 13:00–13:10 B07/205a, Wed 13. 3. 11:30–12:00 B07/205a, 12:00–13:00 B07/217, 12:00–13:00 B07/205a, 13:00–13:10 B07/205a, Wed 20. 3. 11:30–12:00 B07/205a, 12:00–13:00 B07/205a, 12:00–13:00 B07/217, 13:00–13:10 B07/205a, Wed 27. 3. 11:30–12:00 B07/205a, 12:00–13:00 B07/217, 12:00–13:00 B07/205a, 13:00–13:10 B07/205a, Wed 3. 4. 11:30–12:00 B07/205a, 12:00–13:00 B07/205a, 12:00–13:00 B07/217, 13:00–13:10 B07/205a, Wed 10. 4. 11:30–12:00 B07/205a, 12:00–13:00 B07/205a, 12:00–13:00 B07/217, 13:00–13:10 B07/205a, Wed 17. 4. 11:30–12:00 B07/205a, 12:00–13:00 B07/217, 12:00–13:00 B07/205a, 13:00–13:10 B07/205a, Wed 24. 4. 11:30–12:00 B07/205a, 12:00–13:00 B07/205a, 12:00–13:00 B07/217, 13:00–13:10 B07/205a, Wed 15. 5. 11:30–12:00 B07/205a, 12:00–13:00 B07/217, 12:00–13:00 B07/205a, 13:00–13:10 B07/205a, Wed 22. 5. 11:30–12:00 B07/205a, 12:00–13:00 B07/205a, 12:00–13:00 B07/217, 13:00–13:10 B07/205a
Prerequisites (in Czech)
ZLBI0121c Biology I - pract. && ZC011 Handling chemical substances
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- learning the methods of risk evaluation for hereditary diseases of various molecular background in patients based on family anamneses
- understanding the basic principles of gene engineering
- understanding and practising selected molecular methods used for examination of some cancers or hereditary and infectious diseases with regard to the selection of appropriate therapy
Learning outcomes
After completing the course, the student will be able to:
- evaluate the risk of hereditary diseases of various molecular background in patients based on assigned family anamneses of the diseases
- describes the basic principles of genetic prognosis and genetic counselling
- suggest and perform basic molecular-genetic diagnostic examinations of some hereditary, tumour and infectious diseases (PCR, restriction digest, gel electrophoresis), and to interpret the obtained results
- explain selected basic techniques of gene engineering and their application in medicine, and, with knowledge of the used method, to select the clones of cells with an inserted gene
Syllabus
  • Week 1: Genetic disorders - autosomal and gonosomal inheritance
  • Week 2: Extensions to basic genetics
  • Week 3: Genetic prognosis and genetic counselling
  • Week 4: Human population genetics
  • Week 5: Basic methods of molecular biology
  • Week 6: Control test 3 (knowledge from week 1 to week 5 of the spring semester - lectures, practices)
  • Week 7: Gene engineering – production of human proteins in bacterial cells
  • Week 8: Gene engineering – production of human proteins in bacterial cells
  • Week 9: Molecular diagnostics of human pathogenic bacteria
  • Week 10: Molecular diagnostics of human pathogenic bacteria
  • Week 11: Molecular diagnostics of cancer
  • Week 12: Molecular diagnostics of cancer
  • Week 13: Control test 4 (knowledge from week 7 to week 12 of the spring semester - lectures, practices)
  • Week 14: no practices, Re-sit test
  • Week 15: no practices, credit awarding
Literature
    required literature
  • Protokoly ke cvičením jsou dostupné v elektronické podobě v Informačním systému MU ve Studijních materiálech předmětu ZLBI0222c
Teaching methods
laboratory practice, class discussion
Assessment methods
Practical classes are mandatory.
Requirements for course completion: full attendance in the practices (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and checked and signed by appropriate teachers; successfully passed 2 written control tests during the semester (knowledge from lectures and practices, 20 questions in each test, 1 answer correct to be chosen from 4 possibilities, student needs to reach at least 24 points out of 40 from both of the tests). In case you do not pass control tests (you have less than 24 points), you write a re-sit of control test (knowledge from lectures and practices of entire semester, 20 questions, 1 answer correct to be chosen from 4 possibilities, student needs to reach at least 12 points). If you do not pass the re-sit of control test, you have to write the final test (Credit test) based on knowledge of the entire semester lectures and practices. Credit test comprises 20 questions: 10 test questions (multiple answers can be correct, negative marking is obtained for incorrect answers) + 10 given terms for a written explanation. At least 10 points out of 20 are needed to pass.
In case of a student’s late arrival to the practice or poor activity at the practice, the student is required to write an essay in the length of 2 pages on a given topic. Same for the case of two absences in practices (excused or unexcused). Find the instructions for essay writing in the Instructions for the course in Interactive syllabus in the IS. Bring the essay printed to the teacher who specified the topic (after making an appointment in consulting hours), and be ready to answer the teacher's questions regarding the topic.
In case of 3 absences (excused or unexcused), (or more than 3 absences all excused by the Office for Studies within 5 days from the beginning of the absence and introduced to the Information System), it is addressed individually and course-unit credit is awarded only after the proof of the student's knowledge of the entire semester topics (Credit test, see above).
In the case of 4 or more unexcused absences, the course-unit credit is not awarded.
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/med/jaro2024/ZLBI0222c/index_liche.qwarp
Interactive syllabus of the course: https://is.muni.cz/auth/el/med/jaro2024/ZLBI0222c/index_liche.qwarp

What to bring to each practice: printed protocol for the respective practice, your own writing materials. Download the protocol for each practice from the Study materials or Interactive syllabus in the IS, and study it in advance. Lab shoes, lab coats and disposable gloves are not required, but for the tasks with staining, lab coats are recommended.

Substitution of practices: In exceptional cases (illness, appointment at the doctor, once per semester as maximum) student can arrange a substitution with another group. To arrange a substitution, write an e-mail to the contact person of the course at least 24 hours before your planned substitution and specify the group (date and time) you would like to attend instead (see Interactive syllabus - Instructions for the course - Timetable). Substitution is only possible on the same teaching week. When the capacity of the group you intended to substitute with is fully used, the substitution does not need to be approved. Repeated substitution with other groups is not allowed.

Complete Biology instructions to be found at the following link: https://is.muni.cz/auth/el/med/jaro2024/ZLBI0222c/op/Pokyny_ke_cvicenim_z_Biologie.pdf?predmet=1519826

The course is also listed under the following terms Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2025.
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