Bi2MP_GENL Genetics for Basic Education

Faculty of Education
Autumn 2017
Extent and Intensity
0/0/2. 2 credit(s). Type of Completion: z (credit).
Teacher(s)
Mgr. Martina Jančová, Ph.D. (seminar tutor)
Guaranteed by
Mgr. Martina Jančová, Ph.D.
Department of Biology – Faculty of Education
Contact Person: Mgr. Martina Jančová, Ph.D.
Supplier department: Department of Biology – Faculty of Education
Prerequisites (in Czech)
NOW( Bi2MP_GENP Genetics for Basic Educ. )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
At the end of this course, students should be able to:
- solve model examples from genetics of eukaryonts;
- solve model examples from genetics of populations;
- create and analyse a human karyotype;
- identify and specify types of the most frequent chromosomal aberrations;
- explain mechanisms of emergence of chromosomal and genome mutations.
Syllabus
  • 1. Drosophila melanogaster - experimental hybridization. Segregation, combination - examples. Laws of probability calculation – examples.
  • 2. Basic genetic terminology, mutual relations between alleles, genealogy – examples.
  • 3. Mendel’s laws I.: model examples of AD and AR heredity.
  • 4. Mendel’s laws II.: model examples of GD and GR heredity.
  • 5. Genetic prognosis.
  • 6. Eukaryotic chromosomes I.: assembling of karyotypes and their evaluation. Male and female karyotypes.
  • 7. Eukaryotic chromosomes II.: chromosome aberrations at man - examples.
  • 8. Extraction DNA from fruit and vegetable, reversibil denaturation of proteins - experiments. Expression of genetic information, point and chromosomal mutations - examples.
  • 9. Chromosomes, cell cycle - microscopy of Barr body.
  • 10. Deviations from Mendel’s rules: penetrance, expresivity, sex-influenced and -controlled traits, non-allelic genes interaction - examples.
  • 11. Morgan’s laws, genetic bond, strength of the bond, principles of chromosome maps construction. Calculation of Morgan´s and Bateson´s numbers - examples.
  • 12. Population genetics: H.-W. genetic equilibrium - numerical exercises, examples of fixation and displacement of alleles – mutations and selective pressure.
  • 13. Coefficient of affinity and dangers resulting from inbreeding – examples, heredity of quantitative traits at man – observation of dermatoglyphs, examples.
Literature
    recommended literature
  • HAVELKOVÁ, Marie. Pravděpodobnost a její význam v dědičnosti. 3. přeprac. vyd. Brno: Univerzita J.E.Purkyně, 1988, 39 s. info
  • SNUSTAD, D. Peter and Michael J. SIMMONS. Genetika. Translated by Jiřina Relichová. 1. vyd. Brno: Masarykova univerzita, 2009, 871 pp. ISBN 978-80-210-4852-2. Online knihkupectví Munipress info
    not specified
  • KOČÁREK, Eduard. Genetika : obecná genetika a cytogenetika, molekulární biologie, biotechnologie, genomika. Illustrated by Jan Maget. 2. vydání. Praha: Scientia, 2008, 211 stran. ISBN 9788086960364. info
  • ŠMARDA, Jan. Genetika : pro gymnázia. 1. vyd. Praha: Fortuna, 2003, 143 s. ISBN 8071688517. info
  • Praktická cvičení z biologie. Edited by Milan Hejtmánek. 4. vyd. Olomouc: Univerzita Palackého, 1999, 204 s. ISBN 8024400146. info
  • NEČÁSEK, Jan and Ivo CETL. Obecná genetika. 2. vyd. Praha: SPN, 1984, 565 s. URL info
  • NUSSBAUM, Robert L., Roderick R. MCINNES, Huntington F. WILLARD, James THOMPSON and Margaret Wilson THOMPSON. Klinická genetika : Thompson & Thompson. Translated by Petr Goetz. Vyd. 1. Praha: Triton, 2004, 426, lix. ISBN 8072544756. info
  • HAVELKOVÁ, Marie. Analýza příčin drogové závislosti-II. Nové poznatky z molekulární genetiky (Analysis of reasons of drud addiction II. New ideas from molecular genetics). In Podpora a ochrana zdraví dítěte. Praha: Čes. lékařská společnost JEP, 1997, p. 116-209. 25/1. ISBN 80-85783-14-2. info
  • THOMPSON, James S. and Margaret W. THOMPSONOVÁ. Klinická genetika : Genetics in medicine (Orig.). Translated by Viliam Izakovič. 1. vyd. Martin: Vydavateľstvo Osveta, 1988, 437 s. info
  • KING, Robert C. and William D. STANSFIELD. A dictionary of genetics. 6th ed. Oxford: Oxford University Press, 2002, vii, 530. ISBN 0195143256. info
Teaching methods
During practical seminars the examples from genetics of eukaryonts, molecular genetics and genetics of populations will be analysed.
From a given genetic material every student defines normal and pathological human (female and male) karyotype.
Students will microscopically observe cells in different stages of mitotic division.
The seminar will be supported by video programmes from genetic counselling offices and from centres for assisted reproduction.
Assessment methods
Credit.
Student have to fulfil attendance, sumbitt and repair all required protocols and pass a test.
Language of instruction
Czech
Further Comments
The course is taught annually.
The course is taught: every week.
The course is also listed under the following terms Spring 2004, Spring 2005, Spring 2006, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016.
  • Enrolment Statistics (recent)
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