RV2MP_2CG Genetics 2 Practice

Faculty of Education
Spring 2012
Extent and Intensity
0/1/0. 2 credit(s). Type of Completion: k (colloquium).
Teacher(s)
Mgr. et Mgr. Lenka Falk, Ph.D. (seminar tutor)
Guaranteed by
prof. MUDr. Bc. Zuzana Derflerová Brázdová, DrSc.
Department of Health Education – Faculty of Education
Contact Person: Michaela Daňková
Supplier department: Department of Health Education – Faculty of Education
Timetable of Seminar Groups
RV2MP_2CG/01: Thu 9:45–10:30 učebna 27, L. Falk
RV2MP_2CG/02: Thu 10:40–11:25 učebna 27, L. Falk
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
At the end of this course, students should be able to: - understand and explain basic reactions which take place at the cellular level in living organisms - the grounds of cellular and molecular biology and genetics. - illustratively explain the center of a genetic code, its redundancy, universality, cause of origin and consequences of genetic (point) mutations by way of selected examples - describe the expression of genetic information in detail, particularly transcription and translation - explain nucleosome structure of chromosome - describe the course of cellular cycle and analyse the importance of its parts; student can relate the significance of understanding the conception of cellular cycle for applied science and for man’s healthy life – cancer treatment, stem cells, organ transplantation, pharmacogenetics - explain the terms: telomere, apoptosis, necrosis and importance of these structures and processes for cellular (organism’s) senescence and death - understand cell position in multicellular (human) organism, explain illustratively the process of signal reception and processing by cell, matter transport inside and out of a cell and the function of cytosceletal structures in eukaryotic cell.
Syllabus
  • Expression of genetic information – model tasks. Molecular base of genetic, chromosome and genome mutations. News from molecular genetics: human genes for sports performance, for issue of pathological addictions leading to obesity, etc. Types of cells and tissues. Cell in light and electron microscope. Investigation and drawings of chosen histological sections. Fluorescent microscopy – principle, application. Direct and indirect fluorescence. Immunofluorescence. Visualization of microtubules and actin microfilaments by use of fluorescent microscopy. Demonstration of chromosome aberrations by use of fluorescent methods. Types of communication between a cell and a virus. Cell necrosis, cell apoptosis. Destiny of cells in multicellular (human) organism. Demonstrations of practical application of a video during lessons in primary schools with the aim to solve some chosen simple exercises from cytology.
Literature
  • ROSYPAL, Stanislav. Úvod do molekulární biologie (Introduction to molecular biology). Čtvrté inovované vydání. Brno: Prof. RNDr. Stanislav Rosypal, DrSc., Brno, 2006, 290 pp. Díl I. Molekulární biologie prokaryotické buňky. ISBN 80-902562-5-2. URL info
  • CHALUPOVÁ-KARLOVSKÁ, Vlastimila. Obecná biologie : evoluce, biologie buňky, genetika s 558 řešenými testovými otázkami. 1. vyd. Olomouc: Nakladatelství Olomouc, 2004, 206 s. ISBN 8071821748. info
  • HAVELKOVÁ, Marie. Uplatnění nových poznatků molekulární biologie v primární protidrogové prevenci. (Molecular Biology Methods and their Use in Primary Anti-Drug Activities.). In Biochemistry and Molecular Biology on the Threshold of new Century. 1st ed. Brno: Masarykova univerzita, 2000, p. 11-12. ISBN 80-210-2266-3. info
  • Praktická cvičení z biologie. Edited by Milan Hejtmánek. 4. vyd. Olomouc: Univerzita Palackého, 1999, 204 s. ISBN 8024400146. info
  • SVOBODA, Augustin, Jiří ÄDLER, Miroslav GABRIEL, Marie HAVELKOVÁ, Roman JANISCH, Marie KOPECKÁ, Oldřich NEČAS and Jan ŠMARDA. Praktická cvičení z biologie. Protokoly-část I. (Practicals from biology. Protocols-part I.). 1st ed. Brno: Masarykova univerzita, Brno, 1992, 60 pp. skripta. ISBN 80-210-0451-7. info
Teaching methods
The program of practice follows strictly the program of lectures and supplements them with its own selected model experiment and model tasks. In the first part of a term students should put together 50 model tasks and experiments from the cellular and molecular biology/genetics and genetics field of study – transcription and translation of genetic information, DNA replication, point mutation process of origin. In the second part of a term, the topics in question are: surveying of selected histological sections, cells pictures and chosen parts of educational videoprograms that concern chapters on structure and function of various types of human body cells and tissues.
Assessment methods
Credit. At the end of this course, students complete a written test consisting of 50 questions. If they answer 35 questions correctly, they pass the test. After evaluation, a discussion follows in which the correct answers of previously asked questions are repeated and explained again.
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
The course is also listed under the following terms Spring 2008, Spring 2009, Spring 2010, Spring 2011.
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