F1BF1_13 Biophysics

Faculty of Pharmacy
Spring 2025
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
doc. Mgr. Jan Muselík, Ph.D. (lecturer)
PharmDr. Jakub Vysloužil, Ph.D. (lecturer)
Guaranteed by
doc. Mgr. Jan Muselík, Ph.D.
Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy
Supplier department: Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.

The capacity limit for the course is 175 student(s).
Current registration and enrolment status: enrolled: 0/175, only registered: 0/175
fields of study / plans the course is directly associated with
Course objectives

Biophysical principles of function of living systems. Interaction of electromagnetic radiation with living systems. Molecular biophysics. Bioenergetics and interactions of living organisms with the environment. Electrical phenomena. Physical fundamentals of diagnostic methods in medicine. Physical fundamentals of instrumental methods. The statistical methods used in biophysics
Learning outcomes
After completing this course, the student will be able to: - understand the most important biophysical principles and laws; - correctly evaluate the results obtained by basic biophysical methods; - understand the basic knowledge of physiological and molecular biophysics; - understand the importance of biophysical processes for physiology; - understand the principles of some therapeutic and diagnostic medical devices;
Syllabus
  • 1. Introduction, structure of lectures and exercises. Basic statistical concepts and terms.
    2. The statistical methods and their applications.
    3. Structure of the matter. Interaction of matter and electromagnetic radiation. Reactive oxygen species.
    4. Ionizing radiation. types, interaction with matter. Methods of detection. Interaction of ionizing radiation with living matter, its use in medicine.
    5. Non-ionizing electromagnetic radiation. Properties of radiation. Radiation sources and detectors. The influence of visible light, UV radiation and IF radiation to organism.
    6. Molecular biophysics, water and its properties, surface tension, colligative properties, phase interfaces, colloids.
    7. Optical system of the eye. Optics. Optical geometrical devices - microscope, fiber optics - endoscopy.
    8. The properties of gases and liquids, fluid mechanics. Blood flow in the bloodstream. The solubility of gases in liquids, biophysics of breathing.
    9. Biocybernetics.
    10. Acoustics, Ultrasound and its use in pharmacy and medicine.
    11. Biomechanics, physics of bones joints and muscles, mechanical work of the heart.
    12. The cell membrane, electrical phenomena on the membrane, action potentials. Transport phenomena. Use of electric current in medicine.
    13. Magnetism, diagnostic and therapeutic use of magnetic fields. Thermic, temperature regulation of organisms.
Literature
    required literature
  • Hrazdíra I., Mornstein V. Lékařská biofyzika a přístrojová technika. Neptun. Brno 2001. info
  • Dvořák, P., Šucman, E., Kratochvíl, B., Kaláb, P. Praktická cvičení z biofyziky se základy statistiky. VFU Brno, 2005. info
  • Beneš, J., Stránský, P., Vítek, F. Základy lékařské biofyziky. Karolinum Praha, 2005. 196 s. Neptun Brno, 2001. info
    recommended literature
  • kolektiv ( Navrátil, L., Rosina, J.). Lékařskáí biofyzika. Manus Praha, 2003. info
  • Hrazdíra, I., Morstein, V. Úvod do obecné a lékařské biofyziky. MU Brno, 1998. info
  • Javůrek, J. Fototerapie biolaserem. Grada Publishing , AVICENUM Praha, 1995. info
  • Ďoubal, S., Kučová, D. Vybrané kapitoly z fyziky a biofyziky. UK Praha, 1994. info
  • Hrazdíra, I. & kol. Úvod do ultrazvukové diagnostiky. MU Brno, 1993. info
Teaching methods
lectures
Assessment methods
written test
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Teacher's information
The test executes students in accordance to the study plan to the extent specified by syllabus of disciplines and topics of lectures.
The course is also listed under the following terms Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024.
  • Enrolment Statistics (Spring 2025, recent)
  • Permalink: https://is.muni.cz/course/pharm/spring2025/F1BF1_13