F1BF2_13 Biophysics - laboratory practice

Faculty of Pharmacy
Spring 2025
Extent and Intensity
0/2/0. 2 credit(s). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
PharmDr. Jan Elbl, Ph.D. (seminar tutor)
doc. Mgr. Jan Muselík, Ph.D. (seminar tutor)
Guaranteed by
doc. Mgr. Jan Muselík, Ph.D.
Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.

The capacity limit for the course is 96 student(s).
Current registration and enrolment status: enrolled: 0/96, only registered: 0/96
fields of study / plans the course is directly associated with
Course objectives
Physical bases analytical method.
Temperature measuring, density, viscosity, surface tension. Electric metering - conductivity, measurement, metering potential galvanic cell (principles potentiometry),
Optical apparatus - polarimetery, refractometery, nefelometry, laser diffraction, spectrophotometry.

Learning outcomes
At the end of this course the student will be able to: understand biophysical principles and laws; master the basic instrumentation used in biophysical measurements; evaluate the results obtained by basic biophysical methods from a scientific point of view and from the point of view of their application in pharmacy; distinguish the possibilities of using biophysical techniques in practice;
Syllabus
  • 1. A) Polarimetric determination of glucose concentration
    B) Difraction
    C) Refractometry
    2. A) Potentiometric determination of dissociation constants
    B) Buffer capacity
    3. A) Determination of the viscosity
    B) Nephelometry
    4. A) Determination of the critical micelle concentration
    B) Water quality determination by conductivity measurement
    5. A) Determination of the isoelectric point of casein
    B) Measurement of body temperature
    C) Determination of the dissolution rate
    6. Adsorption on activated charcoal
Literature
    required literature
  • Hrazdíra I., Mornstein V. Lékařská biofyzika a přístrojová technika. Neptun. Brno 2001. info
  • Dvořák, P., Šucman, E., Kratochvíl, B., Kaláb, P. Praktická cvičení z biofyziky se základy statistiky. VFU Brno, 2005. info
  • Beneš, J., Stránský, P., Vítek, F. Základy lékařské biofyziky. Karolinum Praha, 2005. 196 s. Neptun Brno, 2001. info
    recommended literature
  • kolektiv ( Navrátil, L., Rosina, J.). Lékařskáí biofyzika. Manus Praha, 2003. info
  • Hrazdíra, I., Morstein, V. Úvod do obecné a lékařské biofyziky. MU Brno, 1998. info
  • Javůrek, J. Fototerapie biolaserem. Grada Publishing , AVICENUM Praha, 1995. info
  • Ďoubal, S., Kučová, D. Vybrané kapitoly z fyziky a biofyziky. UK Praha, 1994. info
  • Hrazdíra, I. & kol. Úvod do ultrazvukové diagnostiky. MU Brno, 1993. info
Teaching methods
laboratory practice
Assessment methods
For credit is necessary to complete all exercises within the scope of the syllabus, and to hand over all properly prepared reports.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Teacher's information
For credit is necessary to complete all exercises within the scope of the syllabus, and to hand over all properly prepared reports.
The course is also listed under the following terms Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024.
  • Enrolment Statistics (Spring 2025, recent)
  • Permalink: https://is.muni.cz/course/pharm/spring2025/F1BF2_13