FaF:FAFG2_12 Pharmacognosy II - Course Information
FAFG2_12 Pharmacognosy II
Faculty of PharmacySpring 2025
- Extent and Intensity
- 2/5/0. 10 credit(s). Type of Completion: zk (examination).
In-person direct teaching - Teacher(s)
- prof. PharmDr. Karel Šmejkal, Ph.D. (lecturer)
prof. PharmDr. Karel Šmejkal, Ph.D. (seminar tutor)
PharmDr. Martin Helcman (seminar tutor)
Mgr. Juraj Markuš (seminar tutor)
Mgr. Polina Shpet (assistant) - Guaranteed by
- prof. PharmDr. Karel Šmejkal, Ph.D.
Department of Natural Drugs – Departments – Faculty of Pharmacy - Prerequisites
- FAFG1_12 Pharmacognosy I
Knowledge of organic chemistry, analytical chemistry, phytochemistry, biochemistry, physiology.
This knowledge will be strictly demanded. - Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
The capacity limit for the course is 24 student(s).
Current registration and enrolment status: enrolled: 0/24, only registered: 0/24 - fields of study / plans the course is directly associated with
- Multidisciplinary studies at Faculty of Pharmacy (programme CST, KOS)
- Pharmacy (programme FaF, M-FARMA)
- Course objectives
- Objectives of Pharmacognosy are to impart knowledges of those drugs of biological origin and their constituents that are of value for their therapeutic, profylactic and diagnostic use in the human and veterinary medicine.
Its scope includes the study of the physical, chemical, biochemical and biological properties of drugs, drug substances, or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources. Research problems in pharmacognosy include studies in the areas of phytochemistry, microbial chemistry, biosynthesis, biotransformation, chemotaxonomy, and other biological and chemical sciences.
Pharmacognosy represents a highly interdisciplinary science which is one of five major areas of pharmaceutical education. - Learning outcomes
- The student must be able to microscopically and macroscopically identify selected drugs, know their main content substances, use, basic biosynthetic reactions, basal classes of secondary metabolites. Know the main plants used in the pharmacy. Chemical characteristics of secondary metabolites, basic knowledge of structure-activity relationships, basic knowledge of adverse effects and interactions.
- Syllabus
- Syllabus of lectures
" Drugs affecting the central and peripheral nervous system
" Drugs affecting vegetative nervous system
" Drugs affecting the cardiovascular system
" Drugs affecting hemocoagulation, fibrinolysis and used as the substitution of blood plasma
" Drugs affecting water balance of the organism
" Drugs affecting the respiratory system
" Drugs affecting the digestive system
" Uterotonics, antiuratics, antiphlogistics
" Dietetics, roborants, geriatrics, sources of vitamins, pomocní léčba od diabetes mellitus
" Hormones, enzymes
" Anti-infectious and anti-invasive drugs
" Drugs used for their local activity
" Biogenic additives
" Natural substances inspirational for synthesis
Laboratory practice summer half
1. Drugs containing saccharides
Identification
Tests of purity
2. Drugs containing polysaccharides and mucilages
Identification
Determination of swelling number
3. Drugs containing phenolic glycosides
Identification
Chromatographic proof of arbutin and hydroquinone
Titrating determination of arbutin
4. Drugs containing cardioglycosides (Control test I)
Identification
Chromatographic proof
Colorimetric determination
5. Drugs containing antraquinone glycosides
Identification
Chromatographic proof
Colorimetric determination of hypericin
6. Drugs containing flavonoid glycosides
Identification
Colorimetric determination of flavonoids
Chromatographic proof
7. Drugs containing saponins (Control test II)
Identification
Determination of hemolytic activity on blood agar
Determination of number of foamability according to Kofler
Determination of glycyrrhizinic acid
8. Drugs containing tannins
Identification - color and precipitation reactions
Chromatographic proof
Colorimetric determination
9. Drugs containing volatiles
Identification
Chromatographic proof
Hydro distillation determination
10. Drugs containing alkaloids I. (Control test III)
Identification ? color and precipitation reactions
Titration determination of tropane alkaloids
11. Drugs containing alkaloids II.
Identification - color and precipitation reactions
Gravimetric determination of purine alkaloids
Thin layer chromatography of poppy opium alkaloids
12. Drugs containing bitter substances
Identification
Determination of number of bitterness
13. Drugs containing mustard glycosides
Identification and purity
14. Drugs containing coumarins, anthocyanins (Control test IV)
Chromatographic proof
- Syllabus of lectures
- Literature
- Teaching methods
- Dialogic (discussion, interview, brainstorming)
Methods of written actions (e.g., for comprehensive exams, final exams)
Demonstration
Exercise and work skills training
Laboratory work - Assessment methods
- Practical examination - recognition of selected drugs, knowledge of content compounds, and their utilization Oral examination
- Language of instruction
- English
- Further comments (probably available only in Czech)
- The course can also be completed outside the examination period.
- Teacher's information
- Required for crediting:
100% attendance of all the practices
Passing the written tests (60% is required to pass)
Required for examination:
Basic knowledge of plant secondary metabolism, structures of pharmaceutically, pharmacologically, or toxicologically important compounds, drugs and plant names, pharmacological or technological effects, and usage, basic methods for identification and quantification.
General examination combining Pharmacognosy I and Pharmacognosy II
Apart of pharmacognosy examination is macroscopic recognition of 10 drugs and microscopic identification of three preparates.
- Enrolment Statistics (Spring 2025, recent)
- Permalink: https://is.muni.cz/course/pharm/spring2025/FAFG2_12