K1PA1_14 Principles of Pathology and Pathophysiology

Faculty of Pharmacy
Spring 2025
Extent and Intensity
2/2/0. 6 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
MUDr. Tomáš Parák, Ph.D. (lecturer)
MUDr. Tomáš Parák, Ph.D. (seminar tutor)
Guaranteed by
MUDr. Tomáš Parák, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Pathology and pathophysiology can be defined as the science of the functions of a diseased organism, at the level of cells, tissues, organs and organ systems. In this course, students will learn about the skin as an organ that provides one of the most important barriers of the human organism, which simultaneously fulfills metabolic, detoxification, resorption and excretory functions. In addition to the basic physiological functions of the skin and skin adnexa, the main skin pathophysiological processes will be discussed, which will be the basis for understanding skin diseases. Other processes that have their skin manifestations will also be mentioned, such as infectious diseases, systemic diseases of the connective tissue and others. Attention will also be paid to damage to the skin by various influences. The course will be focused on a comprehensive understanding of the skin as a necessary system ensuring the integrity of the organism, as well as the important routes of drugs and toxic substances into the organism. Lectures will be supplemented by seminars in which case studies will be presented
Learning outcomes
After completing the course, the student will be able to:
- describe the physiology and pathophysiology of the main organs
- recognize subjective and objective symptoms of diseases
- interpret related examination results
Syllabus
  • Lectures:
  • - Introduction, basic functions of the skin, changes in the skin
  • - Skin as a barrier
  • - Metabolic, excretory and resorption properties of the skin
  • - Skin damage due to physical effects
  • - Subjective and objective symptoms of skin diseases
  • - Skin examination
  • - Localization of skin manifestations
  • - Skin manifestations by body area
  • - Different skin symptoms depending on age and gender
  • - Potentially serious skin diseases
  • - Skin tumors
  • - Cutaneous manifestations of internal diseases
  • - The most common skin diseases
  • - Photosensitivity, skin drug reactions
  • Seminars:
  • - Case studies
Literature
    required literature
  • FÖLSCH, Ulrich R., Kurt KOCHSIEK and Robert F. SCHMIDT. Patologická fyziologie. Translated by Richard Rokyta - Jiří Mareš. Vyd. 1. české. Praha: Grada, 2003, 586 s. ISBN 802470319X. info
  • Vokurka Martin a kol. Patofyziologie pro nelékařské směry. UK Praha, 2014. ISBN 978-80-246-2032-9. info
  • VLAŠÍN, Zdeněk and Hana a kol. JEDLIČKOVÁ. Praktická dermatologie v obrazech a schématech. 1. vydání. Brno: Vladerma, 2001, 251 pp. ISBN 80-238-6966-3. info
Teaching methods
Lectures, seminars, exercises, exercises in selected examination techniques, consultations
Assessment methods
To gain credits: Data analysis, seminar papers on given topics, written test. Completion of the course - in person oral exam
Language of instruction
Czech
Teacher's information
Participation at seminars and excercises 100% and knowledge of recomended literature,content of lectures, seminars and excercises according to the exam questions.
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