FaF:F1OB1_14 Biology - Course Information

F1OB1_14 Biology

Extent and Intensity

2/2/0. 5 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Jana Hložková, Ph.D. (lecturer)
MVDr. Peter Scheer, Ph.D. (lecturer)
MVDr. Jana Hložková, Ph.D. (seminar tutor)
MVDr. Peter Scheer, Ph.D. (seminar tutor)
PharmDr. Tomáš Hammer (seminar tutor)
PharmDr. Mgr. Alžběta Kružicová, Ph.D. (seminar tutor)
PhDr. Gabriela Kuzmínová, MBA (seminar tutor)

Guaranteed by

MVDr. Jana Hložková, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Contact Person: MVDr. Jana Hložková, Ph.D.
Supplier department: Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy

Timetable

Mon 11:30–13:00 45-135

• Timetable of Seminar Groups:

F1OB1_14/01: each odd Monday 8:00–11:00 44-140, T. Hammer, J. Hložková, A. Kružicová, G. Kuzmínová, P. Scheer
F1OB1_14/02: each even Monday 8:00–11:00 44-140, T. Hammer, J. Hložková, A. Kružicová, G. Kuzmínová, P. Scheer
F1OB1_14/03: each odd Thursday 10:00–13:00 44-140, T. Hammer, J. Hložková, A. Kružicová, G. Kuzmínová, P. Scheer
F1OB1_14/04: each even Thursday 10:00–13:00 44-140, T. Hammer, J. Hložková, A. Kružicová, G. Kuzmínová, P. Scheer
F1OB1_14/05: each odd Thursday 13:00–16:00 44-140, T. Hammer, J. Hložková, A. Kružicová, G. Kuzmínová, P. Scheer
F1OB1_14/06: each even Thursday 13:00–16:00 44-140, T. Hammer, J. Hložková, A. Kružicová, G. Kuzmínová, P. Scheer
F1OB1_14/07: each odd Tuesday 13:15–16:15 44-140, T. Hammer, J. Hložková, A. Kružicová, G. Kuzmínová, P. Scheer
F1OB1_14/08: each even Tuesday 13:15–16:15 44-140, T. Hammer, J. Hložková, A. Kružicová, G. Kuzmínová, P. Scheer
F1OB1_14/09: each odd Friday 9:45–12:45 44-140, T. Hammer, J. Hložková, A. Kružicová, G. Kuzmínová, P. Scheer
F1OB1_14/10: each even Friday 9:45–12:45 44-140, T. Hammer, J. Hložková, A. Kružicová, G. Kuzmínová, P. Scheer
F1OB1_14/11: each odd Thursday 7:00–10:00 44-140, T. Hammer, J. Hložková, A. Kružicová, G. Kuzmínová, P. Scheer
F1OB1_14/12: each even Thursday 7:00–10:00 44-140, T. Hammer, J. Hložková, A. Kružicová, G. Kuzmínová, P. Scheer

Prerequisites

FAKULTA(FaF) || OBOR(MUSFaF)
Basic knowledge of biology, biochemistry and physics are required

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Pharmacy (programme FaF, M-FARM)
• Multidisciplinary studies at Faculty of Pharmacy (programme CST, KOS)

Course objectives

The aim of the study is to expand secondary school knowledge of biology so that students gain the necessary basis in terms of content and conceptual area of these disciplines, on the basis of which they could continue to study applied biological disciplines taught at the Faculty of Pharmacy. The study focuses on general, molecular and cellular aspects of biology, evolutionary biology and the basics of genetics. Due to the existence of the compulsory subject Molecular Biology in the 2nd year, this topic is not dealt with more broadly in the subject.

Learning outcomes

Students will gain extended knowledge of basic topics of general and cell biology. Emphasis is placed on the terminology of individual topics, which will allow you to orient and build on them in other related disciplines. The topic of the last lecture opens to students the opportunity to gain insight into the use of biological disciplines in practice. The aim of practical training is to acquire basic manual skills in microscopy and work with biological material.

Syllabus

• 1. Biology introduction to the subject, definition of the field, history, fields of biology, taxonomy, cell types. 2. Possibilities of imaging and imaging techniques in biology 3. Membranes membrane structure (general features + viruses, prokaryotes, eukaryotes), transport across membranes diffusion, osmosis, transport proteins, ion channels and membrane potential, clinically important membranes 4. Organelles, ER, GA, endosomes, lysosomes, peroxisomes, mechanisms of protein transfer into organelles, clinically important organelopathy 5. General principles of intercellular communication in unicellular and multicellular organisms, signaling molecules, receptors associated with ion channels, G-proteins, enzymes, diseases of intercellular communication disorders 6. Cell division - cell cycle (G1, S, G2, M), mitosis (prophase, prometaphase, metaphase, anaphase, telophase, cytokinesis), meiosis, cell cycle regulation 7. Reproduction of organisms asexual reproduction (binary division, gemiparia, fisiparia, vegetative reproduction), sexual reproduction (spermiogenesis, oogenesis, fertilization), gametopathy 8. Introduction to genetics gene, genome, genotype, phenotype, Mendelian genetics, non-Mendelian genetics, epigenetics, transcription, translation, prokaryotic genome, eukaryotic genome, genetic diagnostic tests in medicine. 9. Biology of the immune system (IS) - phylo and ontogenesis of IS, nonspecific and specific immunity, antigen, antibody, opsonization, MHC system, medically important immune disorders, transplant immunity. 10. Interactions of living systems symbiosis, commensalism, infections (prions, viruses, bacteria, parasites) and the environment (ecotoxicology, environmental stress, GMO) 11. Current topics in biomedical fields. 12. Credit granting. Practical excercises I. Microscopic technique 1. Work safety. 2. Organization of teaching, keeping protocols, conditions for granting credits 3. Working with a light microscope 4. Prokaryotic and eukaryotic cell structure. 5. Plant and animal cell structure. II. Prokaryota and protozoa 1. Prokaryota 2. Bacterial smear, Gram staining 3.Sacharomyces smear, staining. 4. Protozoa hay infusion, native preparation 5. Types of movements ciliary, amoeboid, flagellar 6. Staining and morphology of lactic acid bacteria, fixed preparation III. Mitosis 1. Preparation of mitotic preparation, staining 2. Mitotic index 3. Chromosomes of karyotype assembly IV. Meiosis 1. Spermatogenesis 2. Histology of seed-forming epithelium 3. Sperm morphology species differences 4. Oogenesis 5. Ovarian histology 6. Sex chromosomes 7. Detection of Bar's body, preparation of the specimen, staining V. Body structure of mammals 1. Anatomical body structure of a rodent autopsy, video 2. Histological structure of tissues and organs VI. Credit granting 1. Substitute exercises. 2. Checking protocols. 3. Granting of credits.Biology introduction to the subject,

Literature

recommended literature
• Otová B. a kol. Lékařská biologie a genetika I-III. Praha, 2016. URL info
• Otová B.,Mihalová R. Základy biologie a genetiky člověka. Praha, 2014. ISBN 978-80-246-2109-8. info
• Gartner LP, Hiatt JL. Cell biology and histology 7th. London, 2011. ISBN 978-1-4511-8951-3. info
• Jelínek Jan. Biologie a fyziologie člověka a úvod do studia obecné genetiky. Olomouc, 2003. ISBN 80-7182-138-1. info
• Rozsypal S. a kol. Nový přehled biologie. Praha, 2003. ISBN 8071832685. info

Teaching methods

Lectures Discussion, Consultation Demonstration Practical laboratory activities

Assessment methods

Student performance analysis
Analysis of student work products Didactic test

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course can also be completed outside the examination period.

Teacher's information

Complete practical training. Students are required to process protocols. Ending the course: credit and test.

Activity	Difficulty [h]
Domácí příprava na výuku	50
Příprava na zkoušku	100
Summary	150

• Enrolment Statistics (Autumn 2020, recent)
  
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