FaF:FALF1_13 Theory of Dosage Forms - Informace o předmětu
FALF1_13 Theory of Dosage Forms
Farmaceutická fakultapodzim 2022
- Rozsah
- 2/1/0. 4 kr. Ukončení: zk.
- Vyučující
- prof. PharmDr. Mgr. David Vetchý, Ph.D. (přednášející)
doc. PharmDr. Jan Gajdziok, Ph.D. (přednášející)
PharmDr. Jan Elbl, Ph.D. (přednášející)
doc. Mgr. Jan Muselík, Ph.D. (cvičící)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (cvičící) - Garance
- prof. PharmDr. Mgr. David Vetchý, Ph.D.
Ústav farmaceutické technologie – Ústavy – Farmaceutická fakulta - Rozvrh
- Út 15:10–16:50 18-122
- Rozvrh seminárních/paralelních skupin:
- Předpoklady
- FAKULTA(FaF) || OBOR(MUSFaF)
- Omezení zápisu do předmětu
- Předmět je určen pouze studentům mateřských oborů.
- Mateřské obory/plány
- Multidisciplinární studia na farmaceutické fakultě (program CST, KOS)
- Pharmacy (program FaF, M-FARMA)
- Cíle předmětu
- Obligatory subject presenting the basics in medicament formulation, methods and processes useful for their development, polymers suitable for medical form design, stability testing.
- Výstupy z učení
- After completing the course, the student will be able to:
- identify and classify the dosage form into one of the three generations according to the nature of the drug release;
- describe procedures leading to increased bioavailability of drugs;
- describe the production and evaluation of mucoadhesive systems, ion exchangers and biological dosage forms;
- describe the principles of 3D printing for the preparation of dosage forms;
- describe in vitro-in vivo modelsv in drug development - Osnova
- LECTURES:
- Introduction into the pharmaceutical technology, medical forms and drug delivery, the importance of biopharmacy and pharmacokinetics in formulation and development of pharmaceuticals. Generation of medical forms. Medical forms of the first generation.
- Medical forms of the second and the third generation.
- Physico-chemical factors influencing the effect of the drug.
- Biological factors influencing the effect of the drug.
- Preformulation studies, drug formulation, drug validation.
- Increasing bioavailability of poorly water soluble drugs by their modification.
- Increasing bioavailability of poorly water soluble drugs by technological methods facilitating drug dissolution.
- Lipophilic formulations for increasing bioavailability of poorly water-soluble drugs.
- Liquid-solid systems and their application in pharmacy. Medical forms based on these systems.
- Mucoadhesive systems and their application in pharmacy. Medical forms based on these systems.
- 3D printing and its application in pharmacy. Medical forms based on this technology.
- Ion exchangers and their application in pharmacy. Medical forms based on ion exchangers. Production of biological dosage forms.
- In vitro in vivo models in drug development.
PRACTICAL TRAINING: - Surface tension measurement by stalagmometric method.
- Preparation and evaluation of mucoadhesive oral films (MOF).
- Evaluation of aggregate state of suspension.
- Literatura
- povinná literatura
- Sinko, P.T., Singh, Y. Martin's Physical Pharmacy 2011. info
- Výukové metody
- lectures, laboratory exercises
- Metody hodnocení
- credit, oral exam
- Vyučovací jazyk
- Angličtina
- Informace učitele
- Lectures recommended due to lack of suitable literature. Participate in exercises in the full range given by the syllabus and properly prepare protocols from laboratory exercises. Demonstrate ongoing knowledge in the preparation for laboratory exercices. The condition for participation in the exam is to obtain a credit.
- Další komentáře
- Předmět je dovoleno ukončit i mimo zkouškové období.
- Statistika zápisu (podzim 2022, nejnovější)
- Permalink: https://is.muni.cz/predmet/pharm/podzim2022/FALF1_13