F1FM1_14 Pharmacogenomics

Faculty of Pharmacy
Autumn 2023
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
PharmDr. Mgr. Alžběta Kružicová, Ph.D. (lecturer)
Guaranteed by
PharmDr. Mgr. Alžběta Kružicová, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Timetable
Mon 14:55–16:35 44-037
Prerequisites (in Czech)
FAKULTA(FaF) || OBOR(MUSFaF)
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.

The capacity limit for the course is 40 student(s).
Current registration and enrolment status: enrolled: 4/40, only registered: 0/40
fields of study / plans the course is directly associated with
Course objectives
Pharmacogenomics deals with the study of genetic sources of drug response variability. In this subject the students have chance to learn basic genetic factors which determine both drug effectiveness and side effects of this drug. Then genetic factors adjudicate the successfullness of chosen pharmacotherapy.
Syllabus (in Czech)
  • 1. Úvod do studia farmakogenomiky, základní pojmy
    2. Základní principy lidské genetiky/genomiky
    3. Genetika a choroby člověka
    4. Genový polymorfismus, jeho klinický význam
    5. Farmakogenetika a farmakokinetika I
    6. Farmakogenetika a farmakokinetika II
    7. Farmakogenetika a farmakodynamika I
    8. Farmakogenetika a farmakodynamika II
    9. Farmakogenetika a farmakodynamika III
    10. Metody stanovení genových polymorfismů
    11. Bioinformatika
    12. Konzultace
    13. Zkouška
Literature
    recommended literature
  • Strachan a kol. Human Molecular Genetics 3. ISBN 0-8153-4184-9. info
  • Nussbaum a kol. Klinická genetika. ISBN 80-7254-475-6. info
  • Šmarda J. a kol. Metody molekulární biologie. ISBN 80-210-3841-1. info
  • Altman a kol. Principles of Pharmacogenetics and Pharmacogenomics. 2012. ISBN 978-0521885379. info
  • Innocenti Federico a kol. Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response. 2008. ISBN 978-1588296467. info
  • Innocenti Federico. Pharmacogenomics. 2005. ISBN 9781588294401. info
Language of instruction
Czech
Further Comments
Study Materials
The course can also be completed outside the examination period.
Teacher's information
Subject is finished by exam (multiple choice test).
The course is also listed under the following terms Autumn 2022, Autumn 2024.
  • Enrolment Statistics (Autumn 2023, recent)
  • Permalink: https://is.muni.cz/course/pharm/autumn2023/F1FM1_14