F1PC1_14 Human Physiology and Pathophysiology I

Faculty of Pharmacy
Autumn 2023
Extent and Intensity
2/1/0. 4 credit(s). Type of Completion: z (credit).
Teacher(s)
MUDr. Tomáš Parák, Ph.D. (lecturer)
doc. MVDr. Pavel Suchý, Ph.D. (lecturer)
MVDr. Jana Hložková, Ph.D. (seminar tutor)
PharmDr. Mgr. Alžběta Kružicová, Ph.D. (seminar tutor)
MUDr. Tomáš Parák, Ph.D. (seminar tutor)
PharmDr. Lenka Paráková, Ph.D. (seminar tutor)
MVDr. Peter Scheer, Ph.D. (seminar tutor)
MVDr. Lada Tlučhořová (seminar tutor)
Providers of Specific teaching support
Mgr. et Mgr. Iva Raclavská, DiS. (zapisovatel)
Guaranteed by
MUDr. Tomáš Parák, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Supplier department: Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Timetable
Mon 15:25–17:05 45-135
  • Timetable of Seminar Groups:
F1PC1_14/01: each odd Wednesday 7:00–8:40 44-140, T. Parák
F1PC1_14/02: each even Wednesday 7:00–8:40 44-140, T. Parák
F1PC1_14/03: each odd Wednesday 8:55–10:35 44-140, T. Parák
F1PC1_14/04: each even Wednesday 8:55–10:35 44-140, T. Parák
F1PC1_14/05: each odd Wednesday 10:50–12:30 44-140, T. Parák
F1PC1_14/06: each even Wednesday 10:50–12:30 44-140, T. Parák
F1PC1_14/07: each odd Wednesday 13:00–14:40 44-140, T. Parák
F1PC1_14/08: each even Wednesday 13:00–14:40 44-140, T. Parák
F1PC1_14/09: each odd Wednesday 14:55–16:35 44-140, T. Parák
F1PC1_14/10: No timetable has been entered into IS. T. Parák
Prerequisites (in Czech)
FAKULTA(FaF) || OBOR(MUSFaF)
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.

The capacity limit for the course is 160 student(s).
Current registration and enrolment status: enrolled: 115/160, only registered: 0/160
fields of study / plans the course is directly associated with
Course objectives
Human physiology is defined as a science of the functions of healthy organism at the level of cell, tissue, organ and organ systems. Pathophysiology is focused on etiopathogenesis - the mechanisms which lead from the primary cause via individual malfunctions to subsequent development of clinical symptoms of disease. Knowledge of these mechanisms serves to develop a suitable and efficient therapy and prevent resultant damage.
Learning outcomes
After completing the course, the student will be able to: - describe the physiology and pathophysiology of the main organs - recognize subjective and objective symptoms of diseases - examine the main physiological functions - interpret examination results
Syllabus
  • PHYSIOLOGY AND PATHOPHYSIOLOGY I - LECTURES:
    1. Introduction into pathophysiology, symptoms of diseases and their diagnosing. Disease development. Genetic factors in pathogenesis.
    2. General physiological principles. Cell physiology. Function of cell membrane and intracellular structures. Basic principles of physiological regulation.
    3. Nonspecific defence mechanisms. Inflammation. Stress. Damage of organism (physical, chemical and biological)
    4. Specific defensive mechanisms and their disorders. Cell-mediated and antibody immunity. White blood cells, functions and disorders.
    5. Physiology of the locomotive apparatus. Most common diseases of bones, muscles and joints. Inflammatory and degenerative rheumatic diseases.
    6. Physiology of digestion and absorption, metabolism of sacharides, fats and proteins. Nutritional disorders, obesity and starving. Metabolic syndrome.
    7. Vitamins, mineral substances and trace elements. Hyper and hypovitaminoses. Diseases of deficiency and excess of mineral substances and trace elements.
    8. Physiology of blood formation. Differential diagnosing of anaemia.
    9. Hemostasis and hemocoagulation. Coagulation cascade and its disorders. Hemorrhagic and hypercoagulable states.
    10. Physiology of the circulatory system. Formation and development of atherosclerosis. Ischemic heart disease.
    11. Formation and transmission of excitement and its disorders. Inherited and acquired heart disorders.
    12. Basic principles of the blood pressure regulation. Hypertensive disease. Hypotension. Circulation failure (shock).
    13. Theory of the formation of malignant growth. Tumours and their classification. Overview of clinically most common cancers.

    Syllabus of exercises:
    I. Basic physiological functions and their watching
    1. Anamnesis, interview
    2. Objective and subjective anamnesis
    3. Basic checkup (examinations)
    II. Cardiovascular system
    1. Auscultation of heart sounds
    2. Measurement of blood pressure
    3. Electrocardiography
    III. Respiratory system
    1. Auscultation of lungs
    2. Spirometry, Pulse oxymetry
    3. Basal metabolism
    IV. Nervous system
    1. Hearing tests
    2. Eye tests
    3. Optical illusions
    4. EEG
    V. Urogenital tract, diabetes mellitus
    1. Semi-quantitative urinalysis
    2. Specific weight of urine
    3. Kidney functions
    4. Menstrual cycle, ovulation, gravidity
    VI. Blood, Good laboratory practice
    1. Red blood cells
    2. Blood count
    3. Haematocrit
    4. Erythrocyte sedimentation
    5. Differential leukocytes count

    VII. Obtaining credits
Literature
    required literature
  • Trojan S. a kol. Lékařská fyziologie. Paraha. ISBN 9788071690368. info
  • Vokurka Martin a kol. Patofyziologie pro nelékařské směry. UK Praha, 2014. ISBN 978-80-246-2032-9. info
    recommended literature
  • Fölsch U.R. et al. Patologická fyziologie. Praha Grada, 2003. ISBN 80-247-0319-X. info
Teaching methods
Lectures, seminars, exercises, exercises in selected examination techniques, consultations
Assessment methods
To gain credits: Data analysis, eventualyy seminar papers on given topics, written test or an oral exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
Listed among pre-requisites of other courses
Teacher's information
Participation at seminars and excercises 100% and knowledge of recomended literature in the extent of lectures, seminars and excercises of this course are reqired. Without recognition the course or granting the credits is not possible to continue the following course Human Physiology and Pathophysiology II.
The course is also listed under the following terms Autumn 2020, Autumn 2021, Autumn 2022, Autumn 2024.
  • Enrolment Statistics (Autumn 2023, recent)
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