FAVG1_13 Advanced Drug Delivery

Faculty of Pharmacy
Spring 2020
Extent and Intensity
1/2/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. PharmDr. Kateřina Kubová, Ph.D. (lecturer)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (lecturer)
doc. PharmDr. Jan Gajdziok, Ph.D. (seminar tutor)
doc. PharmDr. Kateřina Kubová, Ph.D. (seminar tutor)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (seminar tutor)
PharmDr. Jakub Vysloužil, Ph.D. (seminar tutor)
Guaranteed by
doc. PharmDr. Kateřina Kubová, Ph.D.
Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy
Prerequisites
You can register to this subject only after passing Dosage Forms and Biopharmacy I
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
This eligible subject introduces sophisticated dosage forms with modified drug release based on the present knowledge in biopharmacy and pharmacokinetics. It deals with special technological approaches of their manufacturing and special control methods ensuring their quality.
Syllabus
  • SSYLLABUS OF LECTURES
    1 Matrix tablets.
    2 Multiparticular dosage forms: pellets and their production technologies.
    3 Colonic drug delivery systems
    4 Ocular therapeutic systems.
    5 Modern vaginal systems.
    6 Implants
    7 Modern transdermal systems

    Syllabus of practical training
    Preparation of dosage forms of matrix type and their evaluation.
    Preparation of pellets using rotoagglomeration and their evaluation
    Preparation of pellets using extrusion/spheronization and their evaluation by dissolution test.
    Preparation of pellets by drug solution layering on inactive pellets. Preparation od reservoir-type dosage form with controlled drug release
    Methods for technological parameters evaluation (microscopic analysis, sieve analysis, density, mechanical properties, dissolution methods for drug release testing, etc.).
    Preparation of microparticles by ionic gelation and solvent evaporation method
    Preparation of liquisolid systems
Literature
    recommended literature
  • Wise. Handbook of Pharmaceutical controlled drug release. USA, 2008. ISBN 0-8247-0369-3. info
  • Rathbone, Hadgraft, Roberts. Modified drug delivery technology. USA, 2006. ISBN 0-8247-0869-5. info
  • Edman. Biopharmaceutics of ocular drug delivery. USA, 1993. ISBN 0-8493-7296-8. info
Language of instruction
English
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Teacher's information
oral examination
pacticipation on all practical trainings required
The course is also listed under the following terms Spring 2023, Spring 2024, Spring 2025.
  • Enrolment Statistics (Spring 2020, recent)
  • Permalink: https://is.muni.cz/course/pharm/spring2020/FAVG1_13