FaF:FDAFT_FAF Pharmaceutical Toxicology - Course Information

FDAFT_FAF Pharmaceutical Toxicology

Extent and Intensity

1/1/0. 25 credit(s). Type of Completion: zk (examination).

Guaranteed by

Faculty of Pharmacy

Prerequisites

Basic knowledge of general and special toxicology, physiology, pathophysiology, biochemistry and pathobiochemistry.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

• Safety and Quality of Drugs (programme FaF, D-BKL) (2)

Course objectives

A follow-up of the Master's degree programme deepens students' knowledge of pharmaceutical toxicology and research in the area of evaluation of toxicity of new biologically active substances and undesired drug effects.

Learning outcomes

Advanced knowledge of toxicology focusing on pharmaceutical toxicology, verification of safety of new and potentially effective substances, clinical evaluation of drugs and assessment of their possible side effects.

Syllabus

• Students will obtain theoretical and practical knowledge of toxicological methods used in testing of biologically active substances (potential drugs), on in silico, in vitro and in vivo studies. They will learn about clinical evaluation of new pharmaceutical drugs (especially the first and second phase of clinical evaluation), and about methods monitoring their use in clinical practice, recognize and assess undesired effects and analyze the risk-benefit ratio associated with their use.

Literature

required literature
• Balíková, M. Forenzní a klinická toxikologie. Galén Praha, 2017. ISBN 9788074923043. info
• LEGATH, J., SUCHÝ, P. aj. TOXIKOLOGIA - kompendium pro farmaceuty. Košice, 2016. ISBN 978-80-8077-521-6. info

recommended literature
• Will, Y. Drug discovery toxicology. New Jersey, 2016. info

not specified
• CASARETT DOULL¨S. Essentials of Toxicology. 2010. ISBN 0071742743. info

Teaching methods (in Czech)

Dialogická (diskuze, rozhovor, brainstorming)
Laborování

Assessment methods (in Czech)

Známkou
Ústní zkouška

Language of instruction

Czech

Further comments (probably available only in Czech)

The course can also be completed outside the examination period.

Teacher's information

Mastering basic theoretical knowledge of toxicology within the scope given by the recommended literature.
Consultations with the tutor.
Practical activities in the Institute laboratories, and possibility of internships based on the individual study plan.
The subject has a form of individual study and consultations with the tutor.

Activity	Difficulty [h]
Domácí příprava na výuku	48
Příprava na zápočet	20
Příprava na zkoušku	240
Účast na výuce	16
Summary	324

• Enrolment Statistics (Spring 2020, recent)
  
• Permalink: https://is.muni.cz/course/pharm/spring2020/FDAFT_FAF