F1FT1_14 Pharmacology I

Faculty of Pharmacy
Spring 2021
Extent and Intensity
3/3/0. 7 credit(s). Type of Completion: z (credit).
Teacher(s)
doc. PharmDr. Peter Kollár, Ph.D. (lecturer)
doc. RNDr. Eva Račanská, CSc. (lecturer)
MVDr. Renata Blechová, Ph.D. (seminar tutor)
PharmDr. Bc. Kateřina Horská, Ph.D. (seminar tutor)
MUDr. Marta Chalupová, Ph.D. (seminar tutor)
PharmDr. Tereza Kauerová, Ph.D. (seminar tutor)
PharmDr. Bc. Hana Kotolová, Ph.D. (seminar tutor)
doc. PharmDr. Ondřej Zendulka, Ph.D. (seminar tutor)
doc. PharmDr. Jan Juřica, Ph.D. (lecturer)
Guaranteed by
doc. PharmDr. Peter Kollár, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Supplier department: Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Timetable
Fri 8:00–10:15 44-056
  • Timetable of Seminar Groups:
F1FT1_14/01: Tue 11:45–14:00 44-037, R. Blechová, K. Horská, M. Chalupová, T. Kauerová, H. Kotolová, O. Zendulka
F1FT1_14/02: Thu 7:30–9:45 44-037, R. Blechová, K. Horská, M. Chalupová, T. Kauerová, H. Kotolová, O. Zendulka
F1FT1_14/03: Thu 10:00–12:15 44-037, R. Blechová, K. Horská, M. Chalupová, T. Kauerová, H. Kotolová, O. Zendulka
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
The capacity limit for the course is 160 student(s).
Current registration and enrolment status: enrolled: 3/160, only registered: 0/160, only registered with preference (fields directly associated with the programme): 0/160
fields of study / plans the course is directly associated with
Course objectives
Pharmacology is a science that studies interactions of medical substances and organisms on various morphological and physiological levels. It focuses on mechanisms and time progress of medicines in organisms (pharmacokinetics), and on medicines impact mechanisms on an organism (pharmacodynamics). Certain toxicology sections (science on toxins) constitute a part of the pharmacology in the area of undesirable effects as well.

Learning outcomes
After completing the course the student is able to clarify the basic general rules regarding the fate of the drug in the body and the mechanisms of the drug's effect on the human body. Student can also define and characterize the properties of specific drugs - mechanisms of action, pharmacological effects, pharmacokinetic properties, side effects and interactions. The student will be able to apply the acquired knowledge about the properties of drugs in a safe and effective pharmacotherapy.
Syllabus
  • Lectures spring 2021: Pharmacology I
    Friday 8:00 - 10:15

  • 1st week: 5. 3. 2021
    Introduction into the pharmacology
    Pharmacokinetic processes

  • 2nd week: 12. 3. 2021
    Pharmacokinetic parameters

  • 3rd week: 19. 3. 2021
    Basic pharmacodynamic processes (Dose-drug relationship. Intercellular signaling. Drug-receptor interaction)

  • 4th week: 26. 3. 2021
    Receptor theory. Types of receptors

  • 5th week: 2. 4. 2021
    Easter – Good Friday (public holiday)

  • 6th week: 9. 4. 2021
    Pharmacology of the autonomic nervous system

  • 7th week: 16. 4. 2021
    Factors influencing the effect of a drug (in relation to the drug, the organism, the organism and the drug)

  • 8th week: 23. 4. 2021
    Drugs used in pain therapy (opioid and non - opioid analgesics)

  • 9th week: 30. 4. 2021
    General principles of poisoning therapy. Drug addictions (classification, mechanisms of origin, possibilities of therapy)

  • 10th week: 7. 5. 2021
    Introduction to CNS pharmacology (CNS neurotransmitters. Classification of psychotropic drugs. Psychostimulants. Nootropics. Cognitives. Hypnotics. Sedatives. Anxiolytics)

  • 11th week: 14. 5. 2021
    CNS pharmacology (Antipsychotics and psychodysleptics. Antidepressants and dysphorics)

  • 12th week: 21. 5. 2020
    General anesthetics. Local anesthetics

  • 13th week: 28. 5. 2020
    Antiepileptic drugs. Drugs in Parkinson´s disease


    SEMINARS spring 2021: Pharmacology I
    Tuesday 11:45 – 14:00
    Thursday 7:30 – 9:45, 10:00 – 12:15

  • 1st week: 2., 4. 3. 2021
    Introduction into the pharmacology
    Preclinical and clinical drug testing

  • 2nd week: 9., 11. 3. 2021
    Pharmacokinetic processes

  • 3rd week: 16., 18. 3. 2021
    Pharmacokinetic parameters and their clinical significance

  • 4th week: 23., 25. 3. 2021
    Farmakodynamics

  • 5th week: 30. 3., 1. 4. 2021
    1st control TEST ( topics of the 1st–4th week: Introduction into the pharmacology, Preclinical and clinical drug testing, Pharmacokinetics, Pharmacodynamics - pharmacodynamic processes, receptor theory, types of receptors)
    Vegetative nervous system – sympathetic nervous system

  • 6th week: 6., 8. 4. 2021
    Vegetative nervous system - parasympathetic nervous system

  • 7th week: 13., 15. 4. 2021
    Drugs affecting the urogenital system (Urinary incontinence, benign prostatic hyperplasia, erectile dysfunction)

  • 8th week: 20., 22. 4. 2021
    Drugs used in ophthalmology

  • 9th week: 27., 29. 4. 2021
    2nd control TEST (topics: Vegetative nervous system, Drugs affecting the urogenital system, Drugs used in ophthalmology)
    Analgesics-antipyretics, nonsteroidal antiphlogistics. Antirheumatics. Antiuratics

  • 10th week: 4., 6. 5. 2021
    Analgesics-anodyne

  • 11th week: 11., 13. 5. 2021
    Substances affecting the central nervous system

  • 12th week: 18., 20. 5. 2021
    Myorelaxants. Spasmolytics

  • 13th week: 25., 27. 5. 2021
    3rd control TEST (topics: Pharmacotherapy of pain, Pharmacology of the CNS, General and local anesthetics, Myorelaxants, Spasmolytics)
    Drugs used in dermatology
Literature
    required literature
  • Švihovec Jan a kolektiv. Farmakologie. Grada, Praha, 2018. ISBN 978-80-247-5558-8. URL info
  • Martínková Jiřina a kolektiv. Farmakologie pro studenty zdravotnických oborů. Grada, Praha, 2018. ISBN 978-80-247-4157-4. URL info
  • Lüllmann H., Mohr K., Hein L. Barevný atlas farmakologie. Grada, Praha, 2012. ISBN 978-80-247-3908-3. URL info
    recommended literature
  • Whalen K. Lippincott Illustrated Reviews: Pharmacology, 7th edition. Lippincott Williams & Wilkins, USA, 2018. ISBN 978-1496384133. info
  • Humphrey P. Rang, Maureen M. Dale, James M. Ritter and Rod J. Fl. Rang & Dale's Pharmacology, 8th Edition. 2016. ISBN 978-0702053627. info
  • Trevor A, Katzung B, Masters S., Knuidering-Hall M. Katzung & Trevor's Pharmacology Examination and Board Review. McGraw-Hill Medical, 2012. ISBN 0071789235. info
  • Katzung BG. Basic and Clinical Pharmacology. McGraw-Hill Medical, 2011. ISBN 978-0071764018. info
  • Lincová Dagmar, Farghali, Hassan a kol. Základní a aplikovaná farmakologie. Galén, Praha, 2007. ISBN 9788072623730. info
  • Květina J. a kol. Farmakologie pro farmaceuty 2. díl. VFU Brno, 2003. info
  • Květina J. aa kol. Farmakologie pro farmaceuty 3. díl. VFU Brno, 2000. info
  • Květina J. a kol. Farmakologie pro farmaceuty 1. díl. VFU Brno, 1999. info
Teaching methods
The subject Pharmacology I is taught in the form of online lectures and seminars in the spring semester 2021. The lectures will be recorded. This record can be used as study material for students of Pharmacology I. The record will be uploaded and saved in the Online Teaching section of this course in IS MU for 48 hours after the lecture and will be made available to students of Pharmacology I only for viewing to prevent unauthorized download.
Assessment methods
The criterion for passing the course is to obtain a credit. The condition for obtaining the credit is the fulfillment of attendance at seminars according to the rules below, which are also saved in the Study Materials of the course in the section Organizational Instructions, and successful completion of all three tests during semester. Test questions will be prepared from the topics that are specified in the course syllabus. The tests will include questions with a choice of more correct answers from the options offered. The student get 1 point for a completely correctly answered question. No points will be deducted for an unfilled or incorrectly answered question. The condition for passing the test is to achieve at least 55% of the maximum possible number of points. In case of unsuccessful completion of any of the tests, it will be possible to repeat it, no more than twice in the term announced in the examination period of the same semester (according to the MU Study and Examination Regulations, Article 18). Completion of the credit from the subject Pharmacology I is one of the conditions for taking the exam from the subject Pharmacology II.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2020, Spring 2022, Spring 2023, Spring 2024, Spring 2025.
  • Enrolment Statistics (Spring 2021, recent)
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