FDAAF1_FAF Solid Phase Analysis

Faculty of Pharmacy
Spring 2023
Extent and Intensity
1/1/0. 25 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Jiří Dohnal, CSc., MBA (lecturer)
Guaranteed by
doc. Ing. Jiří Dohnal, CSc., MBA
Faculty of Pharmacy
Prerequisites (in Czech)
FAKULTA(FaF)
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The objectives of the course are listed in the section on learning outcomes.
Learning outcomes
Solid State Analysis By mastering methods and techniques of solid phase analysis and follow-up case studies, the student should have a solid base for solving real problems that can occur during the life cycle management in the pharmaceutical practice.
Syllabus
  • Solid phase analysis - is the latest discipline in pharmaceutical analysis, without which it would not be possible to determine the parameters of drug substances and especially solid dosage forms. The selection of the optimal solid form is a critical aspect of the development of drugs and solid dosage forms. According to the principles of analytical techniques, attention is paid to spectral methods (near and middle infrared spectroscopy in DRIFT or ATR, SS NMR, etc.), diffraction methods (powder X-ray diffraction, laser diffraction, dynamic light scattering, Raman scattering), thermal methods (DSC, TGA, TSC), microscopic methods (optical microscopy and image analysis, electron microscopy) and surface study methods (porosimetry, IGC and DVS).
Literature
    required literature
  • DOHNAL, Jiří a BRUSOVÁ, Hana a GRAFNETTEROVÁ, Taťjana a GRÜNWALD. . Moderní přístupy k farmaceutické analýze: 3. Farmaceutická analýza v pevné fázi. Veterinární a farmaceutická univerzita Brno, 2009. ISBN 978-80-7305-075-7. info
    recommended literature
  • Solid state characterization of pharmaceuticals. Edited by Richard A. Storey - Ingvar Ymen. Chichester, U.K.: John Wiley & Sons, 2011, xx, 506 p. ISBN 9780470659359. info
    not specified
  • Zakrzewski, M. Zakrzewski. Solid State Characterization of Pharmaceuticals. Danbury, 2006. ISBN 1405134941. info
Teaching methods
Teaching is based on consultations and self preparation for the exam. Contact with the teacher is via e-mail and in the form of direct consultations. The system of consultations is individually determined according to the time possibilities of the student and the academic staff member. From the point of view of its monitoring, the study includes an introductory consultation on the subject, consultations related to the professional focus of the student's dissertation and preparation for the exam, assessment of the study result by oral exam.
Assessment methods
Oral exam
Language of instruction
Czech
Further Comments
The course can also be completed outside the examination period.
The course is taught each semester.
The course is also listed under the following terms Autumn 2020, Spring 2021, Autumn 2021, Spring 2022, Autumn 2022, Autumn 2023, Spring 2024, Autumn 2024, Spring 2025.
  • Enrolment Statistics (Spring 2023, recent)
  • Permalink: https://is.muni.cz/course/pharm/spring2023/FDAAF1_FAF