FAFK1_14 Pharmacokinetics

Faculty of Pharmacy
Spring 2024
Extent and Intensity
1/1/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
PharmDr. Tereza Kauerová, Ph.D. (lecturer)
doc. PharmDr. Peter Kollár, Ph.D. (lecturer)
Mgr. Martina Čudová (lecturer)
Mgr. Jana Melicharová (lecturer)
PharmDr. Tereza Kauerová, Ph.D. (seminar tutor)
doc. PharmDr. Peter Kollár, Ph.D. (seminar tutor)
Mgr. Martina Čudová (seminar tutor)
Mgr. Jana Melicharová (seminar tutor)
Guaranteed by
PharmDr. Tereza Kauerová, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Timetable
each even Wednesday 8:00–9:40 44-144
  • Timetable of Seminar Groups:
FAFK1_14/01: each even Wednesday 9:55–11:35 44-144
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.

The capacity limit for the course is 20 student(s).
Current registration and enrolment status: enrolled: 3/20, only registered: 0/20
fields of study / plans the course is directly associated with
Course objectives
Pharmacokinetics course deals with the fundamental principles of absorption, distribution, metabolism, and the elimination of drugs by the human body in time as well as clinical application, including case studies of commonly dosed drugs. Basic aim of education in Pharmacokinetics for students of pharmacy is getting deep knowledge in processes, which take place in relation to time course of drug after administration.
Understanding of pharmacokinetics patterns is important for insight into rational drug dosage in clinical practise. Application of the pharmacokinetic theory to clinical problems involved in optimizing and monitoring drug use in patients is important part of pharmacists work.
Learning outcomes
After completing the course the student is able to explain the general rules regarding the pharmacokinetic processess and clinical significance and application od pharmacokinetic parameters. Student can also define and characterize different factors affecting the drug kinetics and thus pharmacotherapy. The student will be able to apply the acquired knowledge in a safe and effective pharmacotherapy.
Syllabus
  • Introduction to pharmacokinetics (pharmacokinetic processes,basic pharmacokinetic principles)
    Description of the pharmacokinetic processes (absorption, distribution, metabolism, and the excretion of drugs)

    Pharmacokinetic parameters
    (description of pharmacokinetic parameters and their clinical importance)

    Factors of non-genetic origin affecting the drug kinetics
    Factors of genetic origin affecting the drug kinetics

    Pharmacokinetic interactions - description
    Pharmacokinetic interactions - casuistics solution

    Bioequivalence. Pharmacokinetics in the clinical trials.

    TDM - Therapeutic Drug Monitoring (Description and general principles, methodic and procedures of TDM in clinical practice)

    Special kinetics: Cytostatics
    Special kinetics: Antibiotics
Literature
    required literature
  • Whalen K. Lippincott Illustrated Reviews: Pharmacology, 7th edition. Lippincott Williams & Wilkins, USA, 2018. ISBN 978-1496384133. info
  • Humphrey P. Rang, Maureen M. Dale, James M. Ritter and Rod J. Fl. Rang & Dale's Pharmacology, 8th Edition. 2016. ISBN 978-0702053627. info
    recommended literature
  • Trevor A, Katzung B, Masters S., Knuidering-Hall M. Katzung & Trevor's Pharmacology Examination and Board Review. McGraw-Hill Medical, 2012. ISBN 0071789235. info
  • Katzung BG. Basic and Clinical Pharmacology. McGraw-Hill Medical, 2011. ISBN 978-0071764018. info
Teaching methods
lectures, seminars
Assessment methods
The criterion for passing the course is to fulfill the attendance requirement and then to pass the exam test. The condition for passing the exam test is to achieve at least 55% of the maximum possible number of points.
Language of instruction
English
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Teacher's information
Conditions for successful completion of the course and obtaining credits are as follows: 1. Fulfill the course attendance. The absence will be excused by letter of absence or the compensation for the absence would be in the form of a seminar paper on a topic identical to the topic, which a student could not attend. In the case of a long-term serious absence, it will be dealt with individually. 2. To score at least 55% to pass the exam test.
The course is also listed under the following terms Spring 2020, Spring 2022, Spring 2023, Spring 2025.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/pharm/spring2024/FAFK1_14