FAPC2_14 Human Physiology and Pathophysiology II

Faculty of Pharmacy
Spring 2025
Extent and Intensity
2/2/0. 6 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
MUDr. PharmDr. Marek Frydrych, Ph.D. (lecturer)
MUDr. Tomáš Parák, Ph.D. (lecturer)
PharmDr. Lenka Paráková, Ph.D. (lecturer)
MUDr. PharmDr. Marek Frydrych, Ph.D. (seminar tutor)
MVDr. Jana Hložková, Ph.D. (seminar tutor)
MUDr. Marta Chalupová, Ph.D. (seminar tutor)
PharmDr. Mgr. Alžběta Kružicová, Ph.D. (seminar tutor)
MUDr. Tomáš Parák, Ph.D. (seminar tutor)
PharmDr. Lenka Paráková, Ph.D. (seminar tutor)
MVDr. Peter Scheer, Ph.D. (seminar tutor)
RNDr. Jiří Jelínek, Ph.D. (lecturer)
RNDr. Jiří Jelínek, Ph.D. (seminar tutor)
PhDr. Gabriela Kuzmínová, MBA (seminar tutor)
Guaranteed by
MUDr. Tomáš Parák, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Prerequisites (in Czech)
FAPC1_14 Human Physiology and Pathophys
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.

The capacity limit for the course is 24 student(s).
Current registration and enrolment status: enrolled: 0/24, only registered: 0/24
fields of study / plans the course is directly associated with
Course objectives
Human physiology is defined as a science of the functions of healthy organism at the level of cell, tissue, organ and organ systems. Pathophysiology is focused on etiopathogenesis - the mechanisms which lead from the primary cause via individual malfunctions to subsequent development of clinical symptoms of disease. Knowledge of these mechanisms serves to develop a suitable and efficient therapy and prevent resultant damage.
Learning outcomes
After completing the course, the student will be able to: - describe the physiology and pathophysiology of the main organs - recognize subjective and objective symptoms of diseases - examine the main physiological functions - interpret examination results
Syllabus
  • 1. Acute and chronic health failure. Cardiac asthma, pulmonary heart disease.
    2. Gastrointestinal tract and its functions. Pathophysiology of liver and pancreas.
    3. Respiratory system, its functions. Obstructive and degenerative pulmonary processes
    4. Pulmonary hypertension syndrome. Pulmonary TBC. Respiratory
    insufficiency.
    5. Physiology of kidneys and lower urinary tract. Kidney failure.
    6. Basic mechanisms of endocrine regulation, most common disorders. Diabetes mellitus,
    complications.
    7. Physiology of sex hormones and reproductive system.
    8. Physiology of excitable tissue, excitement transmission.
    9. CNS pathophysiology, pain, brain arterial network disorders, consciousness
    10. Physiology and pathophysiology of vegetative nervous
    system
    11. Physiology of the locomotive apparatus.Inflammatory and degenerative diseases.
    12. Skin and skin derivatives, functions and malfunctions. Autoimmune
    diseases
    13. Contaginous and parasitic diseases, anthropozoonoses.
    Temoerature.
    14. Final consultations
    Seminars:
    1. Organization of lessons, work safety, ethical aspects of work with laboratory animals, experimental project, approval process
    2. Collection of biologic. materialand its examination. Laboratory animals - propedeutics. Anesthesia
    3. Imaging techniques in examination, endoscopy. Practical examination methods.
    4. Hormonal processes in the reproductive system. Prenatal diagnostic tests.
    5. Laboratory examination methods - basics of the good laboratory practice, interpretation of results
    6. Laboratory examination methods - microbiological and immunological examination, stress tests, interpreting
    7. Molecular diagnostics and paternity testing
    8. Cytogetetics, chromosomal aberations
    9. Internal environment, acid-base balance. Regulation of blood pressure
    10. Electrophysiological examination methods
    11. Diseases of the circulatory apparatus and the manifestations demonstrated on an experimental model
    12. Visiting Museum of Pathology
    13. Visiting laboratories, experimental models
    14. Course credit approval
Literature
    required literature
  • Silbernagl, S. - Lang, F. Color Atlas of Pathophysiology. 2009. ISBN 978-3-13-116552-7. info
    recommended literature
  • Harrison's principles of internal medicine. Edited by Dan L. Longo - Tinsley Randolph Harrison. 18th ed. New York: McGraw-Hill, 2011, s. xliii. ISBN 9780071748872. info
  • McCance & Huether. Pathophysiology, The Biologic Basis for Disease in Adults and Children. MOSBY, 1994. info
Teaching methods
In person form lectures, seminars, exercises, exercises in selected examination techniques, acquired data analysis, consultations
Assessment methods
For the admission to the exam is necessary 100% participation in the exercises and fulfillment of the assignment of the exercise. Each teacher decides the fulfillment of the obligations arising from the exercises they teach. A seminar thesis on given topics, written test or an interview can be assigned. Completion of the course - oral exam. Students randomly choose three questions from three areas. It is necessary to answer all three questions.
Language of instruction
English
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Teacher's information
Without recognition the previous course Human Physiology and Pathophysiology I or granting the credits of it in winter semester is not possible to continue this course Human Physiology and Pathophysiology II. In this case is also impossible to completion the course by the exam.
The course is also listed under the following terms Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024.
  • Enrolment Statistics (Spring 2025, recent)
  • Permalink: https://is.muni.cz/course/pharm/spring2025/FAPC2_14