CG031 Practical course in modelling of complexes

Faculty of Science
Spring 2025
Extent and Intensity
0/2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: z (credit).
Teacher(s)
doc. Mgr. Jan Paleček, Dr. rer. nat. (seminar tutor)
Guaranteed by
doc. Mgr. Jan Paleček, Dr. rer. nat.
National Centre for Biomolecular Research – Faculty of Science
Contact Person: doc. Mgr. Jan Paleček, Dr. rer. nat.
Supplier department: National Centre for Biomolecular Research – Faculty of Science
Prerequisites
CG030 - Structure and function of protein complexes, students are advised to take Bi9061 - Bioinformatics course.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
The capacity limit for the course is 9 student(s).
Current registration and enrolment status: enrolled: 0/9, only registered: 0/9, only registered with preference (fields directly associated with the programme): 0/9
fields of study / plans the course is directly associated with
Course objectives
Students should learn about protein structure visualization and analysis. They should be able to model protein structures and dock protein-protein interactions.
Learning outcomes
Students will learn about protein structure visualization and analysis. They will be able to model protein structures and dock protein-protein interactions.
Syllabus
  • Introduction of protein structure databases. Editing of pdb files. Protein structure visualization and modeling. Protein docking and protein-protein interaction analysis.
Literature
    recommended literature
  • BEER, de, TAP BERKA, K THORNTON, JM LASKOWSKI and RA. PDBsum additions. Nucleic Acids Research. Oxford: Oxford University Press, 2014, vol. 42, D1, p. "D292"-"D296", 5 pp. ISSN 0305-1048. Available from: https://dx.doi.org/10.1093/nar/gkt940. info
  • JIMENEZ-GARCIA, B PONS and C FERNANDEZ-RECIO. pyDockWEB: a web server for rigid-body protein-protein docking using electrostatics and desolvation scoring. Bioinformatics. Oxford: Oxford University Press, 2013, vol. 29, No 13, p. 1698-1699. ISSN 1367-4803. Available from: https://dx.doi.org/10.1093/bioinformatics/btt262. info
Teaching methods
practical demonstrations and practical work with bioinformatics tools.
Assessment methods
Assessment of final project.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every other week.
Information on course enrolment limitations: Garant si vyhrazuje právo vybrat studenty. Přednost mají studenti s předchozí zkušeností s proteinovými strukturami
The course is also listed under the following terms Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/sci/spring2025/CG031