C7010 Chemical properties, structure and interactions of nucleic acids

Faculty of Science
Autumn 1999
Extent and Intensity
3/1/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. RNDr. Emil Paleček, DrSc. (lecturer)
doc. RNDr. Miroslav Fojta, CSc. (seminar tutor)
Guaranteed by
prof. RNDr. Emil Paleček, DrSc.
Chemistry Section – Faculty of Science
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 18 fields of study the course is directly associated with, display
Syllabus
  • Introduction. Nucleic acids - history. DNA double helix. Isolation and characterisation of nucleic acids. Physical properties of DNA and DNA conformation. Supercoil-stabilised local DNA structures. Nucleases, topoisomerases, helicases, ligases. Covalent interactions of Nas with small molecules. Reversible interactions of small molecules with DNA. Structure of RNA. Methods of nucleic acids analysis. Gene therapy. Oligonucleotides and their analogues. DNA-protein interactions. DNA structure and interactions in biomedicine. Protein p53 and its interactions with DNA.
Language of instruction
Czech
Further Comments
The course is taught annually.
The course is taught: every week.
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.
  • Enrolment Statistics (Autumn 1999, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn1999/C7010