PřF:C7016 Nucleic acids chemistry - Course Information
C7016 Chemical properties, structure and interactions of nucleic acids
Faculty of ScienceAutumn 1999
- Extent and Intensity
- 3/1/0. 4 credit(s). Type of Completion: k (colloquium).
- Teacher(s)
- prof. RNDr. Emil Paleček, DrSc. (lecturer)
- Guaranteed by
- prof. RNDr. Emil Paleček, DrSc.
Chemistry Section – Faculty of Science - Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- Analytical Chemistry (programme PřF, M-CH)
- Analytical Chemistry (programme PřF, N-CH)
- Inorganic Chemistry (programme PřF, M-CH)
- Inorganic Chemistry (programme PřF, N-CH)
- Biochemistry (programme PřF, M-CH)
- Biochemistry (programme PřF, N-CH)
- Physical Chemistry (programme PřF, M-CH)
- Physical Chemistry (programme PřF, N-CH)
- Chemistry (programme PřF, M-CH)
- Environmental Chemistry (programme PřF, M-CH)
- Environmental Chemistry (programme PřF, N-CH)
- Macromolecular Chemistry (programme PřF, M-CH)
- Macromolecular Chemistry (programme PřF, N-CH)
- Organic Chemistry (programme PřF, M-CH)
- Organic Chemistry (programme PřF, N-CH)
- Upper Secondary School Teacher Training in Chemistry (programme PdF, M-CH)
- Upper Secondary School Teacher Training in Chemistry (programme PřF, M-CH)
- Syllabus
- Introduction. Nucleic acids - history. DNA double helix. Isolation and characterisation of nucleic acids. Physical properties of DNA and DNA conformation. Supercoil-stabilised local DNA structures. Nucleases, topoisomerases, helicases, ligases. Covalent interactions of Nas with small molecules. Reversible interactions of small molecules with DNA. Structure of RNA. Methods of nucleic acids analysis. Gene therapy. Oligonucleotides and their analogues. DNA-protein interactions. DNA structure and interactions in biomedicine. Protein p53 and its interactions with DNA.
- Language of instruction
- Czech
- Further Comments
- The course is taught annually.
The course is taught: every week.
- Enrolment Statistics (Autumn 1999, recent)
- Permalink: https://is.muni.cz/course/sci/autumn1999/C7016